High-Level Expression of the Rat Whey Acidic Protein Gene Is Mediated by Elements in the Promoter and 3' Untranslated Region

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

GERM-LINE TRANSFORMATION OF MICE

1986 • 1,165 citations

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane

1989 • 700 citations

Globin gene regulation and switching: Circa 1990

1990 • 463 citations

Human CD2 3′-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

1989 • 385 citations

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

1990 • 337 citations

Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

1984 • 336 citations

Position-effect variegation after 60 years

1990 • 286 citations

Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion.

1985 • 279 citations

Alteration of the quality of milk by expression of sheep β-lactoglobulin in transgenic mice

1987 • 273 citations

The HIV-1 Tat protein: An RNA sequence-specific processivity factor?

1990 • 220 citations

Extracellular matrix and hormones transcriptionally regulate bovine beta-casein 5' sequences in stably transfected mouse mammary cells.

1990 • 217 citations

Complex hormonal regulation of rat casein gene expression.

1982 • 204 citations

Human globin locus activation region (LAR): role in temporal control

1990 • 189 citations

Comparison of the whey acidic protein genra of the rat and mouse

1984 • 176 citations

Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes.

1988 • 161 citations

Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation.

1991 • 143 citations

A novel regulatory mechanism for whey acidic protein gene expression.

1989 • 137 citations

Comparison of the Regulation of the Whey Acidic Protein Gene with that of a Hybrid Gene Containing the Whey Acidic Protein Gene Promoter in Transgenic Mice

1988 • 121 citations

Site-independent expression of the chicken βA-globin gene in transgenic mice

1990 • 106 citations

Tissue-specific expression of the rat β-casein gene in transgenic mice

1988 • 102 citations

Efficient tissue‐specific expression of bovine α‐lactalbumin in transgenic mice

1989 • 96 citations

Tissue-specific, high level expression of the rat whey acidic protien gene in transgenic mice

1990 • 84 citations

A Mammary-Specific Promoter Directs Expression of Growth Hormone not only to the Mammary Gland, but also to Bergman Glia Cells in Transgenic Mice

1991 • 82 citations

Expression of biologically active heterodimeric bovine follicle-stimulating hormone in milk of transgenic mice.

1991 • 59 citations

The mammary gland as a bioreactor: Production of foreign proteins in milk

1990 • 56 citations

Multihormonal Regulation of Milk Protein Gene Expression

1986 • 52 citations

Complete sequence of the rabbit whey acidic protein gene

1990 • 25 citations