Tumor suppression by RNA from the 3′ untranslated region of α-tropomyosin

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member

1992 • 2,719 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

1990 • 1,796 citations

The product of the H19 gene may function as an RNA.

1990 • 1,066 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1992 • 1,031 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

Cytoplasmic activation of human nuclear genes in stable heterocaryons

1983 • 839 citations

Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells

1988 • 832 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

Suppression of Malignancy by Cell Fusion

1969 • 613 citations

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1992 • 543 citations

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development

1989 • 487 citations

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene

1989 • 475 citations

Introduction of a Normal Human Chromosome 11 into a Wilms' Tumor Cell Line Controls Its Tumorigenic Expression

1987 • 407 citations

The molecular basis for tropomyosin isoform diversity

1991 • 350 citations

Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness.

1992 • 337 citations

Absence of TGF-β Receptors and Growth Inhibitory Responses in Retinoblastoma Cells

1988 • 331 citations

Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster.

1985 • 251 citations

Genetic complementation reveals a novel regulatory role for 3? untranslated regions in growth and differentiation

1993 • 245 citations

Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA.

1992 • 228 citations

Differential expression of tropomyosin forms in the microfilaments isolated from normal and transformed rat cultured cells.

1983 • 216 citations

Muscle fiber pattern is independent of cell lineage in postnatal rodent development

1992 • 202 citations

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells

1993 • 199 citations

Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene.

1993 • 175 citations

Suppression of tumorigenicity in simian virus 40-transformed 3T3 cells transfected with alpha-actinin cDNA.

1993 • 156 citations

Suppression of tropomyosin synthesis, a common biochemical feature of oncogenesis by structurally diverse retroviral oncogenes.

1985 • 138 citations

Smooth muscle α-actin is a transformation-sensitive marker for mouse NIH 3T3 and Rat-2 cells

1985 • 136 citations

Tropomyosin isoforms in chicken embryo fibroblasts: purification, characterization, and changes in Rous sarcoma virus-transformed cells.

1985 • 126 citations

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.

1992 • 126 citations

Contractile proteins in human cancer cells. Immunofluorescent and electron microscopic study.

1976 • 118 citations

Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae.

1992 • 118 citations

Evidence for myoblast-extrinsic regulation of slow myosin heavy chain expression during muscle fiber formation in embryonic development.

1993 • 112 citations

Teratocarcinomas and Other Neoplasms as Developmental Defects in Gene Expression

1981 • 109 citations

p53 is covalently linked to 5.8S rRNA.

1992 • 97 citations

Variations in expression of mutant β actin accompanying incremental increases in human fibroblast tumorigenicity

1982 • 91 citations

Suppression of tumor-forming ability and related traits in MCF-7 human breast cancer cells by fusion with immortal mammary epithelial cells.

1990 • 75 citations

Suppression of malignancy in hybrid cells: The mechanism

1985 • 68 citations

Negative control of the helix-loop-helix family of myogenic regulators in the NFB mutant

1990 • 64 citations

Molecular Characterization of the Human trk Oncogene

1986 • 50 citations

Suppression of synthesis and utilization of tropomyosin in mouse and rat fibroblasts by transforming growth factor alpha: a pathway in oncogene action.

1987 • 42 citations

Involvement of vimentin in the reverse transformation reaction.

1989 • 38 citations

Frequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences.

1988 • 37 citations

Expression of the MyoD1 muscle determination gene defines differentiation capability but not tumorigenicity of human rhabdomyosarcomas.

1989 • 34 citations

Chemical carcinogens transform BHK cells by inducing a recessive mutation.

1982 • 31 citations

Suppression of the chemically transformed phenotype of BHK cells by a human cDNA.

1991 • 20 citations

A submicroscopic interstitial deletion of chromosome 14 frequently occurs adjacent to the t(14;18) translocation breakpoint in human follicular lymphoma

1993 • 20 citations

Constitutive gene expression and restoration of the normal phenotype in malignant cells: a model for the origin and evolution of leukemia.

1981 • 10 citations

Reverse Transcriptase Associated with Avian Sarcoma-Leukosis Viruses. III. Influence of Primer Chain Length on the Initiation of DNA Synthesis1

1982 • 10 citations

A cDNA clone with anti-oncogene activity.

1992 • 9 citations

Regulatory proteins for growth and differentiation in normal and leukemic hematopoietic cells: normal differentiation and the uncoupling of controls in myeloid leukemia.

1984 • 1 citations