Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Methods in Yeast Genetics

1988 • 4,905 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

1987 • 2,493 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1989 • 1,237 citations

Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 gene

1979 • 1,080 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Aminoacyl-tRNA Synthetases: General Features and Recognition of Transfer RNAs

1979 • 636 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization

1989 • 392 citations

KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast

1987 • 372 citations

Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28.

1985 • 370 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information.

1988 • 287 citations

Positive regulation in the general amino acid control of Saccharomyces cerevisiae.

1983 • 279 citations

A tail of two src's: Mutatis mutandis

1987 • 278 citations

Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability.

1989 • 278 citations

cAMP-dependent Protein Kinase

1989 • 274 citations

Integration of amino acid biosynthesis into the cell cycle of Saccharomyces cerevisiae

1975 • 252 citations

A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.

1985 • 244 citations

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis.

1989 • 240 citations

The nucleotide sequence of the HIS4 region of yeast

1982 • 233 citations

Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae.

1983 • 231 citations

Positive regulatory interactions of the HIS4 gene of Saccharomyces cerevisiae.

1984 • 166 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

1988 • 162 citations

Control of the yeast cell cycle is associated with assembly/disassembly of the Cdc28 protein kinase complex

1988 • 148 citations

Site-Specific Mutagenesis of cdc2⁺, a Cell Cycle Control Gene of the Fission Yeast Schizosaccharomyces pombe

1986 • 141 citations

raf Family Serine/Threonine Protein Kinases in Mitogen Signal Transduction

1988 • 124 citations

Intracellular Sorting and Processing of a Yeast Vacuolar Hydrolase: Proteinase A Propeptide Contains Vacuolar Targeting Information

1988 • 121 citations

The General Control of Amino Acid Biosynthetic Genes in the Yeast Saccharomyces Cerevisia

1986 • 112 citations

Mutations in the structural genes for eukaryotic initiation factors 2 alpha and 2 beta of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA.

1989 • 102 citations

Growth Factor Receptor Tyrosine Kinases

1988 • 96 citations

Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase.

1988 • 94 citations

Temporal analysis of general control of amino acid biosynthesis in Saccharomyces cerevisiae: role of positive regulatory genes in initiation and maintenance of mRNA derepression.

1984 • 85 citations

Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function.

1988 • 84 citations

Site-specific mutagenesis of cdc2+, a cell cycle control gene of the fission yeast Schizosaccharomyces pombe.

1986 • 82 citations

Protein Serine Threonine Kinases

1987 • 63 citations

Identification and characterization of four new GCD genes in Saccharomyces cerevisiae

1986 • 45 citations

Mechanism of interferon action. The interferon-induced phosphoprotein P1 possesses a double-stranded RNA-dependent ATP-binding site.

1985 • 41 citations

The Protein Kinase C Family: Heterogeneity And Its Implications

1989 • 28 citations

Analysis of the autophosphorylation activity of transformation defective mutants of avian erythroblastosis virus

1986 • 21 citations