Molecular analysis of GCN3, a translational activator of GCN4: evidence for posttranslational control of GCN3 regulatory function.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Methods in Yeast Genetics

1988 • 4,905 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

DNA cloning : a practical approach

1985 • 2,302 citations

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

1979 • 1,504 citations

Synthesis and Processing of Asparagine-Linked Oligosaccharides

1981 • 1,403 citations

Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 gene

1979 • 1,080 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

The detection and classification of membrane-spanning proteins

1985 • 854 citations

Multiple upstream AUG codons mediate translational control of GCN4

1986 • 654 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Evidence for translational regulation of the activator of general amino acid control in yeast.

1984 • 472 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

Rapid and easy sequencing of large linear double-stranded DNA and supercoiled plasmid DNA

1985 • 410 citations

Saturation Mutagenesis of the Yeast his3 Regulatory Site: Requirements for Transcriptional Induction and for Binding by GCN4 Activator Protein

1986 • 352 citations

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.

1986 • 320 citations

A short nucleotide sequence required for regulation of HIS4 by the general control system of yeast

1983 • 288 citations

Positive regulation in the general amino acid control of Saccharomyces cerevisiae.

1983 • 279 citations

5' untranslated sequences are required for the translational control of a yeast regulatory gene.

1984 • 257 citations

A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.

1985 • 244 citations

Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae.

1983 • 231 citations

Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoproteins. Studies with natural and synthetic peptides.

1979 • 197 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

1988 • 162 citations

Linker Tailing: Unphosphorylated Linker Oligonucleotides for Joining DNA Termini

1984 • 154 citations

Site-directed mutagenesis of cytochrome c shows that an invariant Phe is not essential for function

1985 • 151 citations

The General Control of Amino Acid Biosynthetic Genes in the Yeast Saccharomyces Cerevisia

1986 • 112 citations

Multiple GCD genes required for repression of GCN4, a transcriptional activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.

1986 • 100 citations

A segment of GCN4 mRNA containing the upstream AUG codons confers translational control upon a heterologous yeast transcript.

1987 • 89 citations

Physical Analysis of Mating-type Loci in Saccharomyces cerevisiae

1981 • 69 citations

Primary Structural Requirements for the Enzymatic Formation of the N-Glycosidic Bond in Glycoproteins

1979 • 66 citations

Saccharomyces cerevisiae killer virus transcripts contain template-coded polyadenylate tracts.

1984 • 56 citations

Interactions Between Positive and Negative Regulators of GCN4 Controlling Gene Expression and Entry Into the Yeast Cell Cycle

1987 • 41 citations