Folate, Homocysteine and Neural Tube Defects: An Overview

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

The Metabolic Basis of Inherited Disease

1990 • 4,327 citations

Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study

1991 • 3,323 citations

Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

1992 • 3,145 citations

Vitamin Status and Intake as Primary Determinants of Homocysteinemia in an Elderly Population

1993 • 1,920 citations

A Second Common Mutation in the Methylenetetrahydrofolate Reductase Gene: An Additional Risk Factor for Neural-Tube Defects?

1998 • 1,569 citations

Methionine metabolism in mammals

1990 • 1,463 citations

A Second Genetic Polymorphism in Methylenetetrahydrofolate Reductase (MTHFR) Associated with Decreased Enzyme Activity

1998 • 1,283 citations

Greenfield's Neuropathology

1985 • 1,149 citations

Ciba Foundation Symposium

1957 • 1,100 citations

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

1987 • 1,088 citations

Prevention of Neural-Tube Defects with Folic Acid in China

1999 • 1,060 citations

Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

1994 • 881 citations

Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida

1995 • 870 citations

Modern Nutrition in Health and Disease.

1981 • 851 citations

NEUROSURGERY OF INFANCY AND CHILDHOOD

1954 • 797 citations

Potocytosis: Sequestration and Transport of Small Molecules by Caveolae

1992 • 751 citations

Folate Levels and Neural Tube Defects

1995 • 747 citations

Famine and Human Development. The Dutch Hunger Winter of 1944-1945.

1975 • 709 citations

Homocysteine metabolism in pregnancies complicated by neural-tube defects

1995 • 641 citations

Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects

1989 • 629 citations

Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.

1991 • 615 citations

Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase.

1988 • 607 citations

Developmental Neuropathology

1989 • 591 citations

Vitamin dificiencies and neural tube defects.

1976 • 580 citations

The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine

1992 • 562 citations

The organizer factors Chordin and Noggin are required for mouse forebrain development

2000 • 528 citations

FURTHER EXPERIENCE OF VITAMIN SUPPLEMENTATION FOR PREVENTION OF NEURAL TUBE DEFECT RECURRENCES

1983 • 504 citations

Periconceptional Use of Multivitamins and the Occurrence of Neural Tube Defects

1988 • 487 citations

Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects.

1993 • 486 citations

The biological chemistry of folate receptors

1992 • 471 citations

Multivitamin/Folic Acid Supplementation in Early Pregnancy Reduces the Prevalence of Neural Tube Defects

1989 • 462 citations

Folate Receptors

1996 • 449 citations

The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway.

1990 • 444 citations

A Common Variant in Methionine Synthase Reductase Combined with Low Cobalamin (Vitamin B12) Increases Risk for Spina Bifida

1999 • 434 citations

Methionine metabolism in mammals. Distribution of homocysteine between competing pathways.

1984 • 414 citations

Periconceptional Folic Acid Exposure and Risk of Occurrent Neural Tube Defects

1993 • 405 citations

Normal and abnormal development of the human nervous system

1975 • 405 citations

Maternal hyperhomocysteinemia: A risk factor for neural-tube defects?

1994 • 402 citations

PERICONCEPTIONAL VITAMIN USE, DIETARY FOLATE, AND THE OCCURRENCE OF NEURAL TUBE DEFECTS

1995 • 399 citations

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

1996 • 399 citations

Mechanisms of neurulation: traditional viewpoint and recent advances

1990 • 392 citations

Apparent prevention of neural tube defects by periconceptional vitamin supplementation.

1981 • 389 citations

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

1998 • 386 citations

Homocysteine induces congenital defects of the heart and neural tube: Effect of folic acid

1996 • 372 citations

Shroom, a PDZ Domain–Containing Actin-Binding Protein, Is Required for Neural Tube Morphogenesis in Mice

1999 • 366 citations

Dietary folate as a risk factor for neural‐tube defects: evidence from a case‐control study in Western Australia

1989 • 353 citations

FOLIC ACID METABOLISM AND HUMAN EMBRYOPATHY

1965 • 349 citations

Receptor-mediated folate accumulation is regulated by the cellular folate content.

1986 • 348 citations

Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)

1998 • 347 citations

Compartmentation of folate‐mediated one‐carbon metabolism in eukaryotes

1991 • 341 citations

Methionine metabolism in mammals. Adaptation to methionine excess.

1986 • 339 citations

The embryonic development of mammalian neural tube defects

1990 • 337 citations

Method of assay of red cell folate activity and the value of the assay as a test for folate deficiency

1966 • 335 citations

Folylpolyglutamate Synthesis and Role in the Regulation of One-Carbon Metabolism

1989 • 320 citations

A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects

1995 • 314 citations

Changes in the shape of the developing vertebrate nervous system analyzed experimentally, mathematically and by computer simulation

1976 • 294 citations

The Biosynthesis of Spermidine and Spermine from Putrescine and Methionine

1958 • 292 citations

Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects

1999 • 290 citations

Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles.

1988 • 285 citations

Folate in Health and Disease

1995 • 285 citations

The Mechanisms of Neural Tube Formation

1974 • 267 citations

Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

1999 • 261 citations

The Absence of a Relation between the Periconceptional Use of Vitamins and Neural-Tube Defects

1989 • 256 citations

Neural tube defects: A review of human and animal studies on the etiology of neural tube defects

1986 • 249 citations

The “Thermolabile” Variant of Methylenetetrahydrofolate Reductase and Neural Tube Defects: An Evaluation of Genetic Risk and the Relative Importance of the Genotypes of the Embryo and the Mother

1999 • 248 citations

Effect of the notochord on the differentiation of a floor plate area in the neural tube of the chick embryo

1988 • 246 citations

Is the common 677C-->T mutation in the methylenetetrahydrofolate reductase gene a risk factor for neural tube defects? A meta-analysis

1997 • 241 citations

Evidence for Heme-mediated Redox Regulation of Human Cystathionine β-Synthase Activity

1998 • 239 citations

The development of the human brain, the closure of the caudal neuropore, and the beginning of secondary neurulation at stage 12

1987 • 233 citations

Identification of a novel folate receptor, a truncated receptor, and receptor type .beta. in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity

1994 • 229 citations

Neurulation: coming to closure

1997 • 228 citations

Histological and ultrastructural studies of secondary neurulation in mouse embryos

1984 • 225 citations

The regulation of folate and methionine metabolism

1976 • 222 citations

Inositol prevents folate-resistant neural tube defects in the mouse

1997 • 219 citations

Folate intake in Europe: recommended, actual and desired intake

1997 • 219 citations

Notochordal induction of cell wedging in the chick neural plate and its role in neural tube formation

1989 • 218 citations

Enzymatic synthesis of folylpolyglutamates. Characterization of the reaction and its products.

1980 • 215 citations

Folate-Binding Proteins

1990 • 213 citations

THE ROLE OF FOLIC ACID IN PREGNANCY WITH PARTICULAR REFERENCE TO ANAEMIA, ABRUPTION AND ABORTION

1965 • 210 citations

Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism

1993 • 207 citations

Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat

1991 • 207 citations

Feedback inhibition of methylene-tetrahydrofolate reductase in rat liver by S-adenosylmethionine

1967 • 204 citations

Organization and development of the tail bud analyzed with the quail-chick chimaera system

1995 • 203 citations

Enzymatic synthesis and function of folylpolyglutamates

1981 • 203 citations

Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease

1997 • 195 citations

Primary prevention of neural tube defects with folic acid supplementation: Cuban experience

1990 • 190 citations

Methylenetetrahydrofolate Reductase Polymorphism Affects the Change in Homocysteine and Folate Concentrations Resulting from Low Dose Folic Acid Supplementation in Women with Unexplained Recurrent Miscarriages ,

1998 • 173 citations

The vertebrate tail bud: three germ layers from one tissue

1992 • 160 citations

Is disordered folate metabolism the basis for the genetic predisposition to neural tube defects?

1987 • 160 citations

Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: biological significance and implications for improved therapy of human cancer.

1985 • 159 citations

Maternal illness, including fever, and medication use as risk factors for neural tube defects

1998 • 157 citations

Maternal Vitamin Use, Genetic Variation of Infant Methylenetetrahydrofolate Reducatase, and Risk for spina Bifida

1998 • 156 citations

Neural tube defects.

1988 • 155 citations

Decreased methylene tetrahydrofolate reductase activity due to the 677C→T mutation in families with spina bifida offspring

1996 • 154 citations

Quantitative analyses of changes in cell shapes during bending of the avian neural plate

1984 • 152 citations

Clues to the Aetiology of Neural Tube Malformations*

1974 • 148 citations

Spina Bifida and Cranium Bifidum

1943 • 144 citations

The Prognosis of Encephaloceles

1970 • 144 citations

Cloning, mapping and RNA analysis of the human methionine synthase gene

1996 • 144 citations

Increased risk of recurrence of pregnancies complicated by fetal neural tube defects in mothers receiving poor diets, and possible benefit of dietary counselling.

1980 • 141 citations

Clinical, genetic, and epidemiological factors in neural tube defects.

1988 • 139 citations

Characterization of a Mutation in the Reduced Folate Carrier in a Transport Defective L1210 Murine Leukemia Cell Line

1995 • 129 citations

Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects(NTD)

1999 • 127 citations

Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver.

1994 • 126 citations

The gene for cystathionine beta-synthase (CBS) maps to the subtelomeric region on human chromosome 21q and to proximal mouse chromosome 17.

1988 • 126 citations

The Human Cystathionine β-Synthase (CBS) Gene: Complete Sequence, Alternative Splicing, and Polymorphisms

1998 • 122 citations

The folate receptor works in tandem with a probenecid-sensitive carrier in MA104 cells in vitro.

1991 • 122 citations

Intermittent pattern of neural tube closure in two strains of mice

1993 • 119 citations

[84] Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase: A multifunctional protein from porcine liver

1980 • 118 citations

Neural Tube Defects

1988 • 117 citations

Methionine but Not Folinic Acid or Vitamin B-12 Alters the Frequency of Neural Tube Defects in Axd Mutant Mice

1993 • 116 citations

Defects in human methionine synthase in cblG patients

1996 • 115 citations

Interactions of pig liver methylenetetrahydrofolate reductase with methylenetetrahydropteroylpolyglutamate substrates and with dihydropteroylpolyglutamate inhibitors

1980 • 115 citations

Prevention of neural tube defects by and toxicity of <scp>L</scp>‐homocysteine in cultured postimplantation rat embryos

1994 • 113 citations

Disorders of homocysteine metabolism

1997 • 111 citations

Human cystathionine β-synthase cDNA: sequence, alternative splicing and expression in cultured cells

1993 • 108 citations

Role of Mitochondrial and Cytoplasmic Serine Hydroxymethyltransferase Isozymes in de Novo Purine Synthesis in Saccharomyces cerevisiae

1997 • 107 citations

Methionine and neural tube closure in cultured rat embryos: Morphological and biochemical analyses

1990 • 107 citations

The Changing Epidemiology of Neural Tube Defects

1992 • 107 citations

Prevalence of neural tube defects in South Australia, 1966-91: effectiveness and impact of prenatal diagnosis.

1993 • 100 citations

Screening of the C677T mutation on the methylenetetrahydrofolate reductase gene in French patients with neural tube defects

1997 • 98 citations

Expansion of surface epithelium provides the major extrinsic force for bending of the neural plate

1992 • 97 citations

Unrecognised epidemic of anencephaly and spina bifida

1971 • 95 citations

Altered folate and vitamin B12 metabolism in families with spina bifida offspring

1997 • 93 citations

Anencephaly: a review.

1973 • 93 citations

A reexamination of the role of microfilaments in neurulation in the chick embryo

1988 • 93 citations

Impact of Prenatal Diagnosis on the Birth Prevalence of Neural Tube Defects, Atlanta, 1990-4991

1995 • 92 citations

Neural Tube and Craniofacial Defects With Special Emphasis On Folate Pathway Genes

1998 • 92 citations

Clinical role of pteridine therapy in tetrahydrobiopterin deficiency

1985 • 90 citations

Neural‐tube defects and vitamins: the need for a randomized clinical trial

1984 • 89 citations

Purification and Properties of Human Cytosolic Folylpoly-γ-glutamate Synthetase and Organization, Localization, and Differential Splicing of Its Gene

1996 • 89 citations

Evaluation of the MTHFR C677T allele and the MTHFR gene locus in a German spina bifida population

1998 • 89 citations

The role of microfilaments in cranial neurulation in rat embryos: effects of short-term exposure to cytochalasin D

1985 • 87 citations

Studies in neural tube defects I. Epidemiologic and etiologic aspects

1987 • 87 citations

Does lumbosacral spina bifida arise by failure of neural folding or by defective canalisation?

1989 • 84 citations

Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metabolism.

1993 • 83 citations

Cell fractionation and electron microscope studies of kidney folate-binding protein

1991 • 82 citations

Is Myelomeningocele a Disappearing Disease?

1982 • 82 citations

Are common mutations of cystathionine β‐synthase involved in the aetiology of neural tube defects?

1997 • 78 citations

Anencephaly: A Review

1973 • 77 citations

Heterogeneity of neural tube defects in europe: The significance of site of defect and presence of other major anomalies in relation to geographic differences in prevalence

1991 • 77 citations

Genomic organization of the human folate receptor genes on chromosome 11q13

1992 • 77 citations

CHILDREN OF ADULT SURVIVORS WITH SPINA BIFIDA CYSTICA

1973 • 76 citations

Neural-tube defects are associated with low concentrations of cobalamin (vitamin B12) in amniotic fluid

1998 • 76 citations

Methionine and cysteine kinetics at different intakes of methionine and cystine in elderly men and women

1998 • 76 citations

Amniotic fluid folate, vitamin B₁₂ and transcobalamins in neural tube defects

1988 • 76 citations

The C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene is a moderate risk factor for spina bifida in Italy.

1998 • 75 citations

Lack of association between mutations in the folate receptor-alpha gene and spina bifida.

1998 • 74 citations

Shifting genetic patterns in anencephaly and spina bifida.

1978 • 72 citations

The Role of Nutrition in Neural Tube Defects

1990 • 71 citations

Identification of folate binding proteins in rat liver.

1977 • 70 citations

Assignment of the gene for cystathionine ?-synthase to human chromosome 21 in somatic cell hybrids

1984 • 67 citations

Chiari III malformation: imaging features

1992 • 66 citations

Upstream Organization of and Multiple Transcripts from the Human Folylpoly-γ-glutamate Synthetase Gene

1995 • 66 citations

Methionine and cysteine kinetics at different intakes of cystine in healthy adult men

1994 • 65 citations

Response of red blood cell folate to intervention: implications for folate recommendations for the prevention of neural tube defects

2000 • 65 citations

Folate and vitamin B₁₂ concentrations in maternal and fetal blood, and amniotic fluid in second trimester pregnancies complicated by neural tube defects

1992 • 65 citations

Folate status, homocysteine metabolism, and methylene tetrahydrofolate reductase genotype in rural south african blacks with a history of pregnancy complicated by neural tube defects

1999 • 65 citations

Occurrence of neural tube defects among first‐, second‐, and third‐degree relatives of probands: Results of a United States study

1983 • 64 citations

Mechanism of action of cystathionine synthase

1982 • 63 citations

l(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liver

1981 • 62 citations

Is dietary intake of methionine associated with a reduction in risk for neural tube defect-affected pregnancies?

1997 • 62 citations

Selective expression of the high-affinity isoform of the folate receptor (FR-α) in the human placental syncytiotrophoblast and choriocarcinoma cells

1994 • 62 citations

Lack of association between mutations in the folate receptor-? gene and spina bifida

1998 • 60 citations

MTHFR 677C→T mutation, folate intake, neural-tube defect, and risk of cardiovascular disease

1997 • 58 citations

Spatial and Temporal Expression of the Cystathionine β-Synthase Gene During Early Human Development

1999 • 57 citations

Neural tube closure in the chick embryo is multiphasic

1996 • 57 citations

Intestinal Absorption and Malabsorption of Folates

1980 • 56 citations

Bidirectional closure of the rostral neuropore in the human embryo

1989 • 54 citations

Defects in Auxiliary Redox Proteins Lead to Functional Methionine Synthase Deficiency

1997 • 53 citations

Molecular genetic analysis of human folate receptors in neural tube defects

1999 • 53 citations

Elevated midtrimester serum methylmalonic acid levels as a risk factor for neural tube defects

1995 • 52 citations

Exploring gene—gene interactions in the etiology of neural tube defects

1998 • 52 citations

Regulation of folate and one-carbon metabolism in mammalian cells. I. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-gamma-glutamate synthetase activity.

1993 • 50 citations

Functionally Null Mutations in Patients with the cblG-Variant Form of Methionine Synthase Deficiency

1998 • 49 citations

A study of the pattern of prospective somites in the presomitic mesoderm of mouse embryos.

1986 • 48 citations

Outlook for the child with a cephalocele.

1992 • 48 citations

The relationships between vitamin B12 and folic acid and the effect of methionine on folate metabolism

1975 • 47 citations

Epidermal ectoderm is required for full elevation and for convergence during bending of the avian neural plate

1997 • 47 citations

Expression of Escherichia coli folylpolyglutamate synthetase in the Chinese hamster ovary cell mitochondrion

1994 • 46 citations

Study of genetics, epidemiology, and vitamin usage in familial spina bifida in the United States in the 1990s

1994 • 46 citations

Absorption of pteroylpolyglutamates in mothers of infants with neural tube defects

1993 • 42 citations

Investigation of factors influencing folate status in women who have had a neural tube defect‐affected infant

1993 • 42 citations

Stereospecific in vitro embryotoxicity of l-homocysteine in pre- and post-implantation rodent embryos

1993 • 42 citations

The Methylfolate Axis in Neural Tube Defects: In Vitro Characterization and Clinical Investigation

1994 • 41 citations

Cell movements driving neurulation in avian embryos

1991 • 41 citations

Purification of Soluble Cytochrome b 5 as a Component of the Reductive Activation of Porcine Methionine Synthase

1998 • 41 citations

Uptake of oxidized folates by rat liver mitochondria

1981 • 40 citations

Possible interaction of genotypes at cystathionine β‐synthase and methylenetetrahydrofolate reductase (MTHFR) in neural tube defects

1999 • 40 citations

The Declining Prevalence of An en ce p h a Its and Spina Bifida: Its Nature, Causes and lmpl ications

1987 • 40 citations

Epidemic waves in the prevalence of anencephaly and spina bifida in New York State

1973 • 39 citations

Folate Metabolism in Pregnancy

1993 • 39 citations

Structure and regulation of a polymorphic gene encoding folate receptor type gamma/gamma'

1998 • 38 citations

Calcium Regulation of Neural Fold Formation: Visualization of the Actin Cytoskeleton in Living Chick Embryos

1993 • 37 citations

Neural tube defect recurrence after 'partial' vitamin supplementation.

1989 • 37 citations

Possible Abnormalities of Folate and Vitamin B₁₂ Metabolism Associated with Neural Tube Defects^a

1993 • 36 citations

Folate–vitamin B₁₂interrelationships in the central nervous system

1992 • 36 citations

Homocysteine Metabolism in Endothelial Cells of a Patient Homozygous for Cystathionine β-synthase (CS) Deficiency

1997 • 34 citations

Sex Differences in Prevalence of Congenital Neural Defects after Periconceptional Famine Exposure

1997 • 32 citations

Methionine Synthase: High-Resolution Mapping of the Human Gene and Evaluation as a Candidate Locus for Neural Tube Defects

1999 • 32 citations

13C NMR Analysis of the Use of Alternative Donors to the Tetrahydrofolate-Dependent One-Carbon Pools inSaccharomyces cerevisiae

1996 • 31 citations

The Interrelationships among Folate, Vitamin B12, and Methionine Metabolism

1983 • 29 citations

Folic acid absorption in women with a history of pregnancy with neural tube defect

1995 • 29 citations

Neurulation in the rabbit embryo

1998 • 28 citations

Determination of folate transport pathways in cultured rat proximal tubule cells

1998 • 26 citations

Risks in Spina Bifida

1994 • 26 citations

Impaired Regeneration of Monoglutamyl Tetrahydrofolate Leads to Cellular Folate Depletion in Mothers Affected by a Spina Bifida Pregnancy

1998 • 25 citations

Parietal Cephaloceles: Radiographic and Magnetic Resonance Imaging Evaluation

1988 • 24 citations

Risk of Neural Tube Defect-Affected Pregnancy Is Associated with a Block in Maternal One-Carbon Metabolism at the Level ofN-5-Methyltetrahydrofolate:Homocysteine Methyltransferase

1997 • 23 citations

Neural tube defects: prevention by vitamin supplements.

1982 • 23 citations

Anencephaly: its spectrum and relationship to neural tube defects.

1990 • 21 citations

Transcobalamins in the etiology of neural tube defects

1991 • 20 citations

Amniotic Fluid B₁₂And Folate Levels Associated with Neural Tube Defects

1998 • 19 citations

Studies on the mechanisms of neurulation in the chick: Morphometric analysis of force distribution within the neuroepithelium during neural tube formation

1987 • 18 citations

Multi‐site neural tube closure in humans and maternal folate supplementation

1995 • 18 citations

Distribution of alleles of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism in familial spina bifida

1999 • 17 citations

Uptake and Utilization of DL-5-[methyl-14C] Tetrahydropteroylmonoglutamate by Cultured Cytotrophoblasts Associated with Neural Tube Defects

1993 • 16 citations

Folate Binding Proteins

1994 • 15 citations

Methionine adenosyltransferase activity in cultured cells and in human tissues

1991 • 14 citations

Multiple folate transport systems in L1210 cells

1992 • 14 citations

Initial closure of the mesencephalic neural groove in the chick embryo involves a releasing zipping-up mechanism

1997 • 14 citations

Folate supplementation and neural tube defects: a review of a public health issue.

1997 • 9 citations

Human cytosolic folylpoly-γ-glutamate synthase

1997 • 7 citations

An Open Cephalic Neural Tube Reproducibly Induced by Cytochalasin D in Rat Embryos in vitro

1994 • 7 citations

The Regulation of Homocysteine Metabolism

1997 • 6 citations

Enzymatic determination of folylpolyglutamate pools

1997 • 4 citations

Investigation, using rat embryo culture, of the role of methionine supply in folic acid-mediated prevention of neural tube defects

1995 • 2 citations