RACK1, a Receptor for Activated C Kinase and a Homolog of the β Subunit of G Proteins, Inhibits Activity of Src Tyrosine Kinases and Growth of NIH 3T3 Cells

Antibodies, a laboratory manual

1989 • 12,929 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Features of apoptotic cells measured by flow cytometry

1992 • 1,912 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

Three-dimensional structure of the tyrosine kinase c-Src

1997 • 1,402 citations

Regulation, substrates and functions of src

1996 • 1,173 citations

Crystal structure of the Src family tyrosine kinase Hck

1997 • 1,165 citations

The 2.0 Å crystal structure of a heterotrimeric G protein

1996 • 1,118 citations

Localization of Protein Kinases by Anchoring Proteins: a Theme in Signal Transduction

1995 • 911 citations

Src Tyrosine Kinases, Gα Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin

1996 • 770 citations

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.

1994 • 715 citations

Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors

1992 • 703 citations

Association between the PDGF receptor and members of the src family of tyrosine kinases

1990 • 650 citations

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

1987 • 648 citations

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1990 • 629 citations

Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein

1995 • 615 citations

Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin

1995 • 612 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Coordination of Three Signaling Enzymes by AKAP79, a Mammalian Scaffold Protein

1996 • 557 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Identification of intracellular receptor proteins for activated protein kinase C.

1991 • 505 citations

Polyoma virus transforming protein associates with the product of the c-src cellular gene

1983 • 497 citations

Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor

1997 • 456 citations

Using the two-hybrid system to detect protein-protein interactions

1993 • 414 citations

Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

1987 • 410 citations

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

1994 • 407 citations

A target for Src in mitosis

1994 • 361 citations

Phosphorylation of Caveolin by Src Tyrosine Kinases

1996 • 347 citations

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells.

1993 • 338 citations

Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

1984 • 333 citations

C2 Region-derived Peptides Inhibit Translocation and Function of β Protein Kinase C in Vivo

1995 • 322 citations

Crystal Structure at 2.4 Å Resolution of the Complex of Transducin βγ and Its Regulator, Phosducin

1996 • 289 citations

Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis.

1990 • 280 citations

Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.

1994 • 276 citations

Protein Phosphorylation; A Practical Approach

1994 • 273 citations

pp60c-src activation in human colon carcinoma.

1989 • 267 citations

Molecular Glue: Kinase Anchoring and Scaffold Proteins

1996 • 264 citations

Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein

1997 • 254 citations

Multiple integrins mediate cell attachment to cytotactin/tenascin.

1993 • 248 citations

DNA Synthesis Induced by Some but Not All Growth Factors Requires Src Family Protein Tyrosine Kinases

1995 • 244 citations

p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain.

1992 • 212 citations

G Protein Heterodimers: New Structures Propel New Questions

1996 • 204 citations

Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice.

1994 • 203 citations

A synthetic peptide substrate specific for casein kinase II.

1985 • 202 citations

Hold 'em and Fold 'em: Chaperones and Signal Transduction

1995 • 201 citations

Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.

1987 • 179 citations

A Novel src- and ras-suppressed Protein Kinase C Substrate Associated with Cytoskeletal Architecture

1996 • 155 citations

A synthetic peptide derived from p34cdc2 is a specific and efficient substrate of src-family tyrosine kinases.

1992 • 151 citations

Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.

1986 • 147 citations

Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex.

1989 • 129 citations

Agonists and antagonists of protein kinase C function, derived from its binding proteins.

1994 • 125 citations

c-Yes tyrosine kinase activity in human colon carcinoma.

1993 • 108 citations

Interaction of protein kinase C with RACKI, a receptor for activated C-kinase: a role in β protein kinase C mediated signal transduction

1995 • 107 citations

Isolation and Characterization of a Novel Mitogenic Regulatory Gene, 322, Which Is Transcriptionally Suppressed in Cells Transformed by src and ras

1995 • 92 citations

Association between v-Src and Protein Kinase C δ in v-Src-transformed Fibroblasts

1997 • 91 citations

Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association.

1995 • 80 citations

[7] Regulatory subunits of bovine heart and rabbit skeletal muscle cAMP-dependent protein kinase isozymes

1983 • 67 citations

Reversal of EBV Immortalization Precedes Apoptosis in IL-6–Induced Human B Cell Terminal Differentiation

1997 • 61 citations

Structural and Functional Modification of pp60^c-src Associated with Polyoma Middle Tumor Antigen from Infected or Transformed Cells

1985 • 61 citations

p59^fyn Tyrosine Kinase Associates with Multiple T-Cell Receptor Subunits through Its Unique Amino-Terminal Domain

1992 • 58 citations

Src Activity Increases and Yes Activity Decreases during Mitosis of Human Colon Carcinoma Cells

1995 • 54 citations

Signal transduction: Clamping down on Src activity

1997 • 49 citations

Altered Sites of Tyrosine Phosphorylation in pp60^c-src Associated with Polyomavirus Middle Tumor Antigen

1986 • 48 citations

Protein Phosphorylation

1993 • 43 citations

The cpc-2 gene ofNeurospora crassa encodes a protein entirely composed of WD-repeat segments that is involved in general amino acid control and female fertility

1995 • 41 citations

Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo.

1986 • 40 citations

Isolation and characterization of the calcium- and phospholipid-dependent protein kinase (protein kinase C) subtypes from bovine heart

1991 • 35 citations

Subcellular targeting of kinases and phosphatases by association with bifunctional anchoring proteins

1995 • 26 citations

Retrovirus Shuttle Vector for Study of Kinase Activities of pp60^c-src Synthesized In Vitro and Overproduced In Vivo

1986 • 19 citations

Expression of a G-protein β subunit-related gene during lymphocyte activation

1994 • 16 citations