[14]Xenopus oocyte microinjection: From gene to protein

A new and rapid colorimetric determination of acetylcholinesterase activity

1961 • 25,114 citations

Current protocols in molecular biology

1988 • 7,584 citations

A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

1964 • 3,400 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals

1972 • 1,861 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1986 • 979 citations

NUCLEOSIDE PHOSPHOROTHIOATES

1985 • 830 citations

Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α ₂ -Adrenergic Receptor

1987 • 792 citations

Use of Frog Eggs and Oocytes for the Study of Messenger RNA and its Translation in Living Cells

1971 • 774 citations

Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

1989 • 765 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

The Use ofXenopusOocytes for the Study of Ion Channel

1987 • 649 citations

Molecular Cloning of the Thyrotropin Receptor

1989 • 529 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

Molecular characterization of a functional cDNA for rat substance P receptor

1989 • 463 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

Expression of functional acetylcholine receptor from cloned cDNAs

1984 • 366 citations

A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II

1989 • 336 citations

Formation of gap junctions by expression of connexins in Xenopus oocyte pairs

1989 • 317 citations

Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor

1988 • 314 citations

Primary structure and expression of β2: A novel subunit of neuronal nicotinic acetylcholine receptors

1988 • 301 citations

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

1988 • 285 citations

Role of acetylcholine receptor subunits in gating of the channel

1985 • 272 citations

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1989 • 270 citations

Powerful and versatile enhancer-promoter unit for mammalian expression vectors

1986 • 263 citations

Inositol 1,4,5-trisphosphate mimics muscarinic response in Xenopus oocytes

1985 • 249 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides

1989 • 238 citations

The vertebrate neuromuscular junction

1986 • 235 citations

Inhibition of in Vivo and in Vitro Transcription by Monoclonal Antibodies Prepared against Wheat Germ RNA Polymerase II That React with the Heptapeptide Repeat of Eukaryotic RNA Polymerase II

1989 • 228 citations

An Essential Signaling Role for the m ₃ G Cap in the Transport of U1 snRNP to the Nucleus

1990 • 228 citations

The tunicamycins — useful tools for studies on glycoproteins

1981 • 227 citations

The heat-shock response in xenopus oocytes is controlled at the translational level

1982 • 188 citations

Rabbit haemoglobin synthesis in frog cells: the translation of reticulocyte 9 s RNA in frog oocytes

1971 • 181 citations

Identification of a steroid receptor on the surface of Xenopus oocytes by photoaffinity labeling.

1982 • 174 citations

Mutual dependence of Na,K‐ATPase α‐ and β‐subunits for correct posttranslational processing and intracellular transport

1990 • 171 citations

Expression of Functional Cell-Cell Channels from Cloned Rat Liver Gap Junction Complementary DNA

1987 • 166 citations

Expression of functional (Na⁺ + K⁺)‐ATPase from cloned cDNAs

1987 • 165 citations

Molecular distinction between muscarinic acetylcholine receptor subtypes

1987 • 162 citations

Effects of defolliculation on membrane current responses of Xenopus oocytes.

1989 • 147 citations

Genetic Differences in the Ethanol Sensitivity of GABA _A Receptors Expressed in Xenopus Oocytes

1990 • 144 citations

Platelet-Derived Growth Factor A Chain Is Maternally Encoded in Xenopus Embryos

1988 • 141 citations

Protein synthesis during maturation promoting factor- and progesterone-induced maturation in Xenopus oocytes

1982 • 138 citations

The use of Xenopus oocytes to probe synaptic communication

1988 • 138 citations

ELECTRON MICROSCOPE RADIOAUTOGRAPHY AS A QUANTITATIVE TOOL IN ENZYME CYTOCHEMISTRY

1967 • 127 citations

Radiochemical assay for ACh: modifications for sub‐picomole measurements

1977 • 122 citations

Polar asymmetry in the organization of the cortical cytokeratin system of Xenopus laevis oocytes and embryos

1987 • 119 citations

Quantitative hybridization-arrant of mRNA InXenopusoocytes using single-tiranded coanplementary DNA or ollgonudeotlde probes

1985 • 111 citations

The Biosynthesis of Biologically Active Proteins in mRNA-MicroinjectedXenopusOocyte

1985 • 111 citations

Sequence organization of the poly(A) RNA synthesized and accumulated in lampbrush chromosome stage Xenopus laevis oocytes

1982 • 106 citations

At least two mRNA species contribute to the properties of rat brain A-type potassium channel expressed in xenopus oocytes

1988 • 104 citations

Functional analysis of mutant Xenopus U2 snRNAs

1989 • 103 citations

pH changes associated with meiotic maturation in oocytes of Xenopus laevis

1981 • 103 citations

Fidia Research Foundation neuroscience award lectures

1987 • 99 citations

Fidia Research Foundation Neuroscience award lectures

1991 • 99 citations

Evidence for the involvement of more than one mRNA species in controlling the inactivation process of rat and rabbit brain Na channels expressed in Xenopus oocytes

1988 • 97 citations

The mechanism for increased protein synthesis during Xenopus oocyte maturation

1982 • 96 citations

The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles.

1990 • 96 citations

Heterologous Expression of Excitability Proteins: Route to More Specific Drugs?

1988 • 95 citations

Rat brain 5-HT1C receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes

1987 • 91 citations

Quantitative simulation of endplate currents at neuromuscular junctions based on the reaction of acetylcholine with acetylcholine receptor and acetylcholinesterase

1979 • 89 citations

Effect of the cap structure on pre-mRNA splicing in Xenopus oocyte nuclei.

1989 • 83 citations

Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase, and butyrylcholinesterase on cultured myotubes.

1986 • 83 citations

Differention of the animal-vegetal axis in Xenopus laevis oocytes

1987 • 82 citations

Transient localizations of messenger RNA in Xenopus laevis oocytes

1982 • 81 citations

Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue

1986 • 80 citations

The Regulatory Function of Poly(A) and Adjacent 3' Sequences in Translated RNA

1982 • 80 citations

Assembly and N-glycosylation of all ACh receptor subunits are required for their efficient insertion into plasma membranes

1989 • 79 citations

Cytosine methylation in CTF and Spl recognition sites of an HSV tk promoter: effects on transcriptionin vivoand on factor bindingin vitro

1989 • 79 citations

Xenopus laevis oocyte calmodulin in the process of meiotic maturation.

1980 • 76 citations

Aggregates of acetylcholinesterase induced by acetylcholine receptor-aggregating factor

1985 • 76 citations

Decreased TRH Receptor mRNA Activity Precedes Homologous Downregulation: Assay in Oocytes

1987 • 74 citations

Diacylglycerol production in Xenopus laevis oocytes after microinjection of p21ras proteins is a consequence of activation of phosphatidylcholine metabolism.

1990 • 72 citations

Interspersed poly(A) RNAs of amphibian oocytes are not translatable

1984 • 68 citations

Binding to membrane proteins within the endoplasmic reticulum cannot explain the retention of the glucose-regulated protein GRP78 in Xenopus oocytes.

1988 • 67 citations

Angiotensin II-Induced Calcium Mobilization in Oocytes by Signal Transfer Through Gap Junctions

1990 • 67 citations

Anion transport in oocytes of Xenopus laevis induced by expression of mouse erythroid band 3 protein--encoding cRNA and of a cRNA derivative obtained by site-directed mutagenesis at the stilbene disulfonate binding site.

1989 • 66 citations

Developmentally regulated RNA binding proteins during oogenesis in Xenopus laevis.

1983 • 66 citations

U2 snRNA sequences that bind U2-specific proteins are dispensable for the function of U2 snRNP in splicing.

1989 • 64 citations

Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing.

1990 • 59 citations

Expression of cholinesterase gene(s) in human brain tissues: translational evidence for multiple mRNA species.

1984 • 58 citations

Site-directed mutagenesis of Asp-376, the catalytic phosphorylation site, and Lys-507, the putative ATP-binding site, of the α-subunit of Torpedo californica

1990 • 56 citations

Recombinant human acetylcholinesterase is secreted from transiently transfected 293 cells as a soluble globular enzyme

1991 • 55 citations

Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro.

1990 • 52 citations

Identification by site-directed mutagenesis of Lys-558 as the covalent attachment site of H2DIDS in the mouse erythroid band 3 protein

1989 • 51 citations

Intercellular junctions between the follicle cells and oocytes of Xenopus laevis

1984 • 50 citations

Equilibrium properties of mouse-Torpedo acetylcholine receptor hybrids expressed in Xenopus oocytes.

1987 • 49 citations

Induction of cell–cell channel formation by mRNA

1981 • 49 citations

Impact of altered protein structures on the intracellular traffic of a mutated vasopressin precursor from Brattleboro rats

1989 • 48 citations

Accurate, TATA box-dependent polymerase III transcription from promoters of the c-myc gene in injected Xenopus oocytes.

1989 • 47 citations

Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations.

1990 • 46 citations

Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors.

1990 • 45 citations

Secreted alkaline phosphatase: an internal standard for expression of injected mRNAs in the Xenopus oocyte

1990 • 40 citations

Modulation of poly(A)(+)mRNA-metabolizing and transporting systems under special consideration of microtubule protein and actin

1983 • 38 citations

Microinjection of a Conserved Peptide Sequence of p34 ^cdc2 Induces a Ca ²⁺ Transient in Oocytes

1990 • 37 citations

Purification of a p47 phosphoprotein from Xenopus laevis oocytes and identification as an in vivo and in vitro p34^cdc2 substrate

1989 • 37 citations

Hormonal effects on RNA synthesis by stage 6 oocytes of Xenopus laevis

1975 • 37 citations

Functional activity of oligosaccharide‐deficient (Na,K)ATPase expressed in Xenopus oocytes

1988 • 37 citations

Calcium mobilization by angiotensin II and neurotransmitter receptors expressed in Xenopus laevis oocytes

1988 • 35 citations

Expression and Tissue-specific Assembly of Human Butyrylcholine Esterase in Microinjected Xenopus laevis Oocytes

1989 • 34 citations

Expression of the thyroid sodium/iodide symporter in Xenopus laevis oocytes

1989 • 32 citations

Effect of tunicamycin on the expression of functional brain neurotransmitter receptors and voltage-operated channels in Xenopus oocytes

1988 • 29 citations

Aspartate‐70 to glycine substitution confers resistance to naturally occurring and synthetic anionic‐site ligands on inovo produced human butyrylcholinesterase

1990 • 29 citations

Efficient functioning of plant promoters and poly(A) sites inXenopusoocytes

1989 • 28 citations

Molecular Biology Approach to the Neurosciences

1985 • 27 citations

Expression of mouse-Torpedo acetylcholine receptor subunit chimeras and hybrids in Xenopus oocytes

1987 • 24 citations

Expression of a Human Cocaine‐Sensitive Dopamine Transporter in Xenopus laevis Oocytes

1990 • 24 citations

Premature Termination of Transcription Can Be Induced on an Injected α-Tubulin Gene in Xenopus Oocytes

1990 • 23 citations

Characterization of the soluble cyclic nucleotide phosphodiesterases in xenopus laevis oocytes

1982 • 21 citations

Single RNA species injected in Xenopus oocyte directs the synthesis of active choline acetyltransferase

1988 • 19 citations

Changes of alanine-sodium co-transport during maturation of xenopus laevis oocytes

1983 • 18 citations

Persistence of nonribosome bound 5 S RNA in full-grown oocytes of Xenopus laevis

1982 • 18 citations

Effects of butyrate upon the metaphase‐specific deacetylation of histone H4

1981 • 16 citations

Modifications in oocyte protein synthesis induced by progesterone in Xenopus laevis

1981 • 15 citations

Biochemical characterization of lysosomes in unfertilized eggs of xenopus laevis

1979 • 14 citations

The use of mRNA translationin vitro andin ovo followed by crossed immunoelectrophoretic autoradiography to study the biosynthesis of human cholinesterases

1986 • 14 citations

Trifluoperazine‐induced meiotic maturation in Xenopus laevis

1982 • 14 citations

A comparison of Xenopus laevis oocyte and embryo mRNA

1981 • 13 citations

Carbon dioxide reversibly inhibits meiosis of Xenopus laevis oocyte and the appearance of the maturation promoting factor

1982 • 13 citations

Tissue-specific processing and polarized compartmentalization of clone-produced cholinesterase in microinjectedXenopus oocytes

1989 • 13 citations

Improving poor in vitro transcription from G,C-rich genes

1990 • 13 citations

Functional reconstitution of fMet-Leu-Phe receptor in Xenopus laevis oocytes.

1990 • 12 citations

An oocyte-expressed α-Dublin gene inXenopus laevis, sequences required for the initiation of transcription

1989 • 12 citations

In vitro Induction of Germinal Vesicle Breakdown in Xenopus laevis Oocytes by Melittin

1982 • 11 citations

Mobilization of maternal mRNA in amphibian eggs with special reference to the possible role of membraneous supramolecular structures

1983 • 10 citations

Induction of meiosis of Xenopus laevis oocytes by mianserine

1981 • 10 citations

Premature termination of transcription can be induced on an injected alpha-tubulin gene in Xenopus oocytes.

1990 • 9 citations

Coinjection of Xenopus Oocytes With cDNA-Produced and Native mRNAs: A Molecular Biological Approach to the Tissue-Specific Processing of Human Cholinesterases

1990 • 8 citations

Effect of calmodulin inhibitor, Stelazine, on the endocytosis of vitellogenin and transglutaminase activity in Xenopus laevis O�cytes

1982 • 7 citations

trans activation of rat phosphoenolpyruvate carboxykinase (GTP) gene expression by micro-coinjection of rat liver mRNA in Xenopus laevis oocytes.

1989 • 4 citations

Accumulation, spatial distribution and partial characterization of poly(A)+RNA in the developing oocytes of Xenopus laevis

1981 • 4 citations

Evidence for a novel growth factor in xenopus oocytes

1989 • 4 citations