Aspartate‐70 to glycine substitution confers resistance to naturally occurring and synthetic anionic‐site ligands on inovo produced human butyrylcholinesterase

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states

1987 • 1,044 citations

The biology of cholinesterases

1974 • 897 citations

A METHOD FOR THE DETECTION OF ATYPICAL FORMS OF HUMAN SERUM CHOLINESTERASE. DETERMINATION OF DIBUCAINE NUMBERS

1957 • 476 citations

Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence

1986 • 426 citations

The Ace locus of Drosophila melanogaster: structural gene for acetylcholinesterase with an unusual 5′ leader.

1986 • 270 citations

Cholinesterase in embryonic development.

1975 • 267 citations

Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.

1990 • 208 citations

Cholinesterase in Embronic Development

1975 • 192 citations

Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase.

1989 • 191 citations

Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues.

1987 • 176 citations

Structure of the gene for human butyrylcholinesterase. Evidence for a single copy

1990 • 161 citations

The Plasma Cholinesterases: A New Perspective

1981 • 158 citations

Monographs in Human Genetics

1972 • 156 citations

The acetylcholinesterase-inhibitory activity of steroidal glycoalkaloids and their aglycones

1989 • 134 citations

The Biosynthesis of Biologically Active Proteins in mRNA-MicroinjectedXenopusOocyte

1985 • 111 citations

De novo amplification within a "silent" human cholinesterase gene in a family subjected to prolonged exposure to organophosphorous insecticides.

1989 • 84 citations

Vertebrate Cholinesterases: Structure and Types of Interaction

1988 • 84 citations

Differential inhibition of the serum cholinesterase phenotypes by solanine and solanidine

1962 • 60 citations

Polymorphism of Acetylcholinesterase in Discrete Regions of the Developing Human Fetal Brain

1985 • 53 citations

Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro.

1990 • 52 citations

Onchidal: a naturally occurring irreversible inhibitor of acetylcholinesterase with a novel mechanism of action.

1989 • 50 citations

Amplification of butyrylcholinesterase and acetylcholinesterase genes in normal and tumor tissues: putative relationship to organophosphorous poisoning.

1990 • 47 citations

Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors.

1990 • 45 citations

Differential Response of Human Serum Cholinesterase Types to an Inhibitor in Potato

1959 • 37 citations

Teratogenicity of the solatium alkaloid solasodine and of ‘Kennebec’ potato sprouts in hamsters

1976 • 37 citations

Catalysis by acetylcholinesterase. Acceleration of the hydrolysis of neutral acetic acid esters by certain aromatic cations.

1977 • 36 citations

Expression and Tissue-specific Assembly of Human Butyrylcholine Esterase in Microinjected Xenopus laevis Oocytes

1989 • 34 citations

Cholinoceptive properties of human primordial, preantral, and antral oocytes: In situ hybridization and biochemical evidence for expression of cholinesterase genes

1989 • 28 citations

Pyridine-2-Aldoxime Methiodide and Diacetyl Monoxime against Organophosphorus Poisoning

1958 • 28 citations

Reciprocal regulation of acetylcholinesterase and butyrylcholinesterase in mammalian skeletal muscle

1987 • 27 citations

Expression of cholinesterase genes in human oocytes revealed by in-situ hybridization

1987 • 18 citations

Cholinoceptive properties of human primordial, preantral, and antral oocytes: In situ hybridization and biochemical evidence for expression of cholinesterase genes

1989 • 16 citations

Improving poor in vitro transcription from G,C-rich genes

1990 • 13 citations

A note on suxamethonium sensitivity and serum cholinesterase variants

1976 • 12 citations

Cross‐Homologies and Structural Differences Between Human Cholinesterases Revealed by Antibodies Against cDNA‐Produced Human Butyrylcholinesterase Peptides

1988 • 12 citations

The influence of oximes on the acetylthiocholine hydrolysis rate

1963 • 5 citations