An Essential Signaling Role for the m ₃ G Cap in the Transport of U1 snRNP to the Nucleus

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

Major nucleolar proteins shuttle between nucleus and cytoplasm

1989 • 1,113 citations

Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.

1981 • 725 citations

A trans-spliced leader sequence on actin mRNA in C. elegans

1987 • 639 citations

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen

1984 • 566 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Movement of a karyophilic protein through the nuclear pores of oocytes.

1984 • 510 citations

Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding

1986 • 386 citations

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

1984 • 371 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

A nuclear extract of xenopus laevis oocytes that accurately transcribes 5S RNA genes

1978 • 323 citations

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

1989 • 314 citations

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

1985 • 307 citations

Identification of specific binding proteins for a nuclear location sequence

1989 • 219 citations

Differentiation of Cells of the Rana pipiens Gastrula in Unconditioned Medium1

1959 • 198 citations

Gamma-monomethyl phosphate: a cap structure in spliceosomal U6 small nuclear RNA.

1989 • 185 citations

Nucleocytoplasmic distribution of snRNPs and stockpiled snRNA-binding proteins during oogenesis and early development in Xenopus laevis

1983 • 182 citations

Nucleocytoplasmic segregation of proteins and RNAs

1983 • 163 citations

The C. elegans Trans-spliced leader RNA is bound to Sm and has a trimethylguanosine cap

1988 • 139 citations

A monoclonal antibody against 2,2,7‐trimethylguanosine that reacts with intact, class U, small nuclear ribonucleoproteins as well as with 7‐methylguanosine‐capped RNAs

1987 • 133 citations

Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-Sm and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal antibodies.

1986 • 87 citations

Reconstitution of the U1 small nuclear ribonucleoprotein particle.

1987 • 72 citations

Cytoplasmic assembly of snRNP particles from stored proteins and newly transcribed snRNA's in L929 mouse fibroblasts

1988 • 70 citations

Assembly of Functional U1 and U2 Human-Amphibian Hybrid snRNPs in Xenopus laevis oocytes

1988 • 60 citations

trans-splicing in nematodes

1989 • 53 citations

Localization and structure of snRNPs during mitosis

1985 • 46 citations

Nuclear transport

1989 • 43 citations

Monoclonal antibody against non-histone chromosomal protein high mobility group 1 Co-migrates with high mobility group 1 into the nucleus.

1986 • 38 citations

Phenylalanine transfer ribonucleic acid from Escherichia coli B, isolation and characterization of oligonucleotides from ribonuclease T1 and ribonuclease A hydrolyzates

1969 • 34 citations

RNA processing and ribonucleoprotein assembly studied in vivo by RNA transfection.

1990 • 31 citations

Antibodies distinguishing between intact and alkali-hydrolyzed 7-methylguanosine

1978 • 26 citations

Synthesis ofN²,N², 7-trimethylguanosine cap derivatives

1989 • 13 citations