CD27low CD4 T Lymphocytes That Accumulate in the Mouse Lungs during Mycobacterial Infection Differentiate from CD27high Precursors In Situ, Produce IFN-γ, and Protect the Host against Tuberculosis Infection

Dendritic cells and the control of immunity

1998 • 14,345 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2004 • 2,462 citations

An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection.

1993 • 2,410 citations

Disseminated tuberculosis in interferon gamma gene-disrupted mice.

1993 • 1,982 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

T-Cell Function and Migration — Two Sides of the Same Coin

2000 • 1,437 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

TNF/TNFR FAMILY MEMBERS IN COSTIMULATION OF T CELL RESPONSES

2004 • 1,320 citations

Immune cell migration in inflammation: present and future therapeutic targets

2005 • 1,262 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Helper T Cell Differentiation Is Controlled by the Cell Cycle

1998 • 862 citations

CD27 is required for generation and long-term maintenance of T cell immunity

2000 • 726 citations

I<scp>mmunity to</scp>T<scp>uberculosis</scp>

2004 • 680 citations

Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death

1998 • 597 citations

Characterization of CD4+ CTLs Ex Vivo

2002 • 535 citations

The Relative Importance of T Cell Subsets in Immunity and Immunopathology of Airborne Mycobacterium tuberculosis Infection in Mice

2001 • 527 citations

Interaction of NF-κB and NFAT with the Interferon-γ Promoter

1997 • 427 citations

Lymphocyte life-span and memory

1994 • 405 citations

CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool

2003 • 355 citations

Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells

2000 • 340 citations

CD4 Effector T Cell Subsets in the Response to Influenza

2002 • 328 citations

Distinct lineages of TH1 cells have differential capacities for memory cell generation in vivo

2002 • 289 citations

Protection from Respiratory Virus Infections Can Be Mediated by Antigen-Specific Cd4+ T Cells That Persist in the Lungs

2001 • 285 citations

Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor

1993 • 280 citations

Dynamics and Requirements of T Cell Clonal Expansion In Vivo at the Single-Cell Level: Effector Function Is Linked to Proliferative Capacity

1999 • 253 citations

Expression of the Chemokine Receptors CCR4, CCR5, and CXCR3 by Human Tissue-Infiltrating Lymphocytes

2002 • 244 citations

CD27, a Member of the Tumor Necrosis Factor Receptor Superfamily, Activates NF-κB and Stress-activated Protein Kinase/c-Jun N-terminal Kinase via TRAF2, TRAF5, and NF-κB-inducing Kinase

1998 • 239 citations

Constitutive CD27/CD70 Interaction Induces Expansion of Effector-Type T Cells and Results in IFNγ-Mediated B Cell Depletion

2001 • 237 citations

Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions

2002 • 231 citations

Expression of the Murine CD27 Ligand CD70 In Vitro and In Vivo

2003 • 193 citations

Characterization of the human CD27 ligand, a novel member of the TNF gene family.

1994 • 171 citations

The many faces of host responses to tuberculosis

2001 • 159 citations

CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis

2002 • 157 citations

The CD27⁻ subset of peripheral blood memory CD4⁺ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo

1992 • 157 citations

Complex Memory T-Cell Phenotypes Revealed by Coexpression of CD62L and CCR7

2005 • 128 citations

The Size and Phenotype of Virus-Specific T Cell Populations Is Determined by Repetitive Antigenic Stimulation and Environmental Cytokines

2004 • 121 citations

CD70+ antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa

2005 • 106 citations

Phenotypic classification of human CD8⁺ T cells reflecting their function: inverse correlation between quantitative expression of CD27 and cytotoxic effector function

2004 • 101 citations

Multigenic Control of Disease Severity after VirulentMycobacterium tuberculosisInfection in Mice

2002 • 96 citations

Novel phenotypes and migratory properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue

2005 • 89 citations

Persistence and Turnover of Antigen-Specific CD4 T Cells During Chronic Tuberculosis Infection in the Mouse

2003 • 87 citations

Severity of Tuberculosis in Mice is Linked to Distal Chromosome 3 and Proximal Chromosome 9

1999 • 85 citations

Comparative Analysis of T Lymphocytes Recovered from the Lungs of Mice Genetically Susceptible, Resistant, and Hyperresistant toMycobacterium tuberculosis-Triggered Disease

2000 • 76 citations

Comparative analysis of mycobacterial infections in susceptible I/St and resistant A/Sn inbred mice

2000 • 62 citations

Lung cell responses toM. tuberculosisin genetically susceptible and resistant mice following intratracheal challenge

2003 • 55 citations

The Functional Heterogeneity of Type 1 Effector T Cells in Response to Infection Is Related to the Potential for IFN-γ Production

2005 • 53 citations

T Cell Memory in the Lung Airways

2005 • 52 citations

CD4 T cells producing IFN-γin the lungs of mice challenged with mycobacteria express a CD27-negative phenotype

2004 • 28 citations