Distinct lineages of TH1 cells have differential capacities for memory cell generation in vivo

A new mathematical model for relative quantification in real-time RT-PCR

2001 • 32,396 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

2000 • 3,456 citations

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

1997 • 2,317 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

Cytokines Induce the Development of Functionally Heterogeneous T Helper Cell Subsets

1998 • 1,569 citations

Antibodies to interleukin 12 abrogate established experimental colitis in mice.

1995 • 1,338 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells

1997 • 1,022 citations

T CELL MEMORY

1998 • 863 citations

Helper T Cell Differentiation Is Controlled by the Cell Cycle

1998 • 862 citations

Role of T-bet in Commitment of T _H 1 Cells Before IL-12-Dependent Selection

2001 • 813 citations

Signaling and Transcription in T Helper Development

2000 • 635 citations

Immunogenicity and protective efficacy of a tuberculosis DNA vaccine

1996 • 629 citations

Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory

2001 • 600 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

1995 • 560 citations

Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.

1995 • 554 citations

T Cell Memory

2002 • 529 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Early Transcription and Silencing of Cytokine Genes Underlie Polarization of T Helper Cell Subsets

2001 • 498 citations

Unequal Death in T Helper Cell (Th)1 and Th2 Effectors: Th1, but not Th2, Effectors Undergo Rapid Fas/FasL-mediated Apoptosis

1997 • 460 citations

Class II-Independent Generation of CD4 Memory T Cells from Effectors

1999 • 422 citations

Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes

1999 • 393 citations

Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

1998 • 332 citations

Modelling T-cell memory by genetic marking of memory T cells in vivo

1999 • 310 citations

Cutting Edge: IL-12 Is Required for the Maintenance of IFN-γ Production in T Cells Mediating Chronic Resistance to the Intracellular Pathogen,Toxoplasma gondii

2000 • 296 citations

Qualitative Changes Accompany Memory T Cell Generation: Faster, More Effective Responses at Lower Doses of Antigen

2000 • 285 citations

Generation and in vivo persistence of polarized Th1 and Th2 memory cells

1994 • 283 citations

Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection

1998 • 238 citations

IL-12 Is Required to Maintain a Th1 Response DuringLeishmania majorInfection

2000 • 207 citations

The role of antigen and IL-12 in sustaining Th1 memory cellsin vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge

2000 • 193 citations

Immunobiology of lnterleukin-12

1998 • 191 citations

Instruction for Cytokine Expression in T Helper Lymphocytes in Relation to Proliferation and Cell Cycle Progression

1999 • 190 citations

CD4+ T cell effectors can become memory cells with high efficiency and without further division

2001 • 186 citations

Migration and Function of Antigen-Primed Nonpolarized T Lymphocytes in Vivo

2001 • 176 citations

Vaccination with Heat-killed Leishmania Antigen or Recombinant Leishmanial Protein and CpG Oligodeoxynucleotides Induces Long-Term Memory CD4+and CD8+T Cell Responses and Protection Against Leishmania major Infection

2002 • 171 citations

Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.

1995 • 146 citations

Heterogeneity of the Memory CD4 T Cell Response: Persisting Effectors and Resting Memory T Cells

2001 • 121 citations

In Vivo Priming of Cd4 T Cells That Produce Interleukin (Il)-2 but Not IL-4 or Interferon (Ifn)-γ, and Can Subsequently Differentiate into IL-4–Or IFN-γ–Secreting Cells

2001 • 113 citations

Endogenous IL-12 Is Required for Induction and Expression of Experimental Autoimmune Uveitis

1998 • 110 citations

In differentiated CD4⁺T Cells, interleukin 4 production is cytokine-autonomous, whereas interferon γ production is cytokine-dependent

1997 • 90 citations

Withdrawal of Stimulation May Initiate the Transition of Effector to Memory CD4 Cells

2002 • 58 citations

Antigen challenge leads toin vivoactivation and elimination of highly polarized TH1 memory T cells

2002 • 56 citations

Antigen-Specific T Helper Cell Function

2000 • 45 citations

Analysis and sorting of T cells according to cytokine expression.

1998 • 20 citations

Persistence of Pathogenic CD4+ Th1-Like Cells In Vivo in the Absence of IL-12 but in the Presence of Autoantigen

2001 • 15 citations

Differentiated Th1 autoreactive effector cells can induce experimental autoimmune encephalomyelitis in the absence of IL-12 and CD40/CD40L interactions

2002 • 14 citations