Novel phenotypes and migratory properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

2004 • 2,910 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Skewed maturation of memory HIV-specific CD8 T lymphocytes

2001 • 1,025 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

1994 • 630 citations

Human cerebrospinal fluid central memory CD4⁺T cells: Evidence for trafficking through choroid plexus and meninges via P-selectin

2003 • 508 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

Progressive differentiation and selection of the fittest in the immune response

2002 • 503 citations

Class II-Independent Generation of CD4 Memory T Cells from Effectors

1999 • 422 citations

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor.

1994 • 418 citations

Functional Responses and Costimulator Dependence of Memory CD4+ T Cells

2000 • 318 citations

Activated Primary and Memory CD8 T Cells Migrate to Nonlymphoid Tissues Regardless of Site of Activation or Tissue of Origin

2004 • 282 citations

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1989 • 237 citations

Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells.

1990 • 236 citations

CD4+ T cell effectors can become memory cells with high efficiency and without further division

2001 • 186 citations

Phenotypic heterogeneity of antigen‐specific CD4 T cells under different conditions of antigen persistence and antigen load

2004 • 184 citations

Entry of naive CD4 T cells into peripheral lymph nodes requires L-selectin.

1994 • 182 citations

Functional Subsets of Memory T Cells Identified by CCR7 Expression

2000 • 148 citations

Evidence for differential expression of CD45 isoforms by precursors for memory-dependent and independent cytotoxic responses: human CD8 memory CTLp selectively express CD45R0 (UCHL1)

1989 • 138 citations

Heterogeneity of the Memory CD4 T Cell Response: Persisting Effectors and Resting Memory T Cells

2001 • 121 citations

Cutting Edge: L-Selectin (CD62L) Expression Distinguishes Small Resting Memory CD4+ T Cells That Preferentially Respond to Recall Antigen

2003 • 114 citations

Functionally Heterogeneous CD8⁺T-Cell Memory Is Induced by Sendai Virus Infection of Mice

1999 • 79 citations

Functional plasticity of an antigen-specific memory CD4 T cell population

2002 • 73 citations

Effector CD4 T Cells Are Biochemically Distinct from the Memory Subset: Evidence for Long-Term Persistence of Effectors In Vivo

1999 • 60 citations

Anatomical Heterogeneity of Memory CD4+ T Cells Due to Reversible Adaptation to the Microenvironment

2004 • 50 citations

T Cell Memory: Heterogeneity and Mechanisms

2000 • 40 citations

Modulation of Memory CD4 T Cell Function and Survival Potential by Altering the Strength of the Recall Stimulus

2005 • 32 citations

Amplified ELISPOT assay for the detection of HIV-specific antibody-secreting cells in subhuman primates

1992 • 31 citations

Association of Gag‐Specific T Lymphocyte Responses during the Early Phase of Human Immunodeficiency Virus Type 1 Infection and Lower Virus Load Set Point

2002 • 29 citations