cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

The Pharmacological Basis of Therapeutics

1986 • 2,365 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Cloning and expression of cDNA for a human thromboxane A2 receptor

1991 • 680 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat

1992 • 645 citations

Structural requirements of N-glycosylation of proteins. Studies with proline peptides as conformational probes

1983 • 606 citations

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

1993 • 546 citations

Substrate specificity of protein kinase C

1986 • 521 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

1993 • 475 citations

Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.

1993 • 381 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP3 subtype.

1992 • 353 citations

Structure of the Adrenergic and Related Receptors

1989 • 300 citations

Comprehensive medicinal chemistry

1991 • 278 citations

EIGHTH GADDUM MEMORIAL LECTURE UNIVERSITY OF LONDON INSTITUTE OF EDUCATION DECEMBER 1980: BIOLOGICAL IMPORTANCE OF PROSTACYCLIN

1982 • 276 citations

Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells.

1992 • 259 citations

Thromboxane, Prostaglandin and Leukotriene Receptors

1989 • 258 citations

Prostacyclin is a specific effector of adipose cell differentiation. Its dual role as a cAMP- and Ca(2+)-elevating agent.

1992 • 167 citations

Mouse thromboxane A2 receptor: cDNA cloning, expression and Northern blot analysis

1992 • 162 citations

Characterization of receptors involved in the direct and indirect actions of prostaglandins E and I on the guinea‐pig ileum

1992 • 154 citations

Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis.

1993 • 137 citations

Synthetic peptides corresponding to the site phosphorylated in 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as substrates of cyclic nucleotide-dependent protein kinases.

1986 • 116 citations

Cholera Toxin Induces cAMP-independent Degradation of Gs

1989 • 104 citations

Functional and ligand binding studies suggest heterogeneity of platelet prostacyclin receptors

1989 • 87 citations

Identification of the prostacyclin receptor by radiation inactivation.

1984 • 63 citations

Solubilization of prostacyclin membrane receptors from human platelets

1989 • 49 citations

Identification and characterisation of a prostacyclin- like receptor in bovine coronary arteries using a specific and stable prostacyclin analogue, ciloprost, as radioactive ligand

1982 • 48 citations

Prostaglandin production by phagocytic cells of the mouse thymic reticulum in culture and its modulation by indomethacin and corticosteroids.

1985 • 48 citations

Identification of a prostacyclin receptor coupled to the adenylate cyclase system via a stimulatory GTP-binding protein in mouse mastocytoma P-815 cells

1990 • 46 citations

EFFECTS OF PROSTAGLANDINS AND THROMBOXANE ANALOGUES ON BULLOCK AND DOG IRIS SPHINCTER PREPARATIONS

1982 • 41 citations

Characterization of prostaglandin and thromboxane receptors expressed on a megakaryoblastic leukemia cell line, MEG-01s

1991 • 38 citations

Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways

1992 • 36 citations

Lymphocytes and arachidonic acid metabolism.

1988 • 35 citations

Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture.

1991 • 34 citations

Involvement of protein kinase C in prostaglandin E2-induced catecholamine release from cultured bovine adrenal chromaffin cells.

1990 • 30 citations

(5Z)‐carbacyclin discriminates between prostacyclin‐receptors coupled to adenylate cyclase in vascular smooth muscle and platelets

1987 • 30 citations

Prostacyclin binding to guinea pig pulmonary receptors

1981 • 28 citations

Use of the rabbit transverse stomach-strip to identify and assay prostacyclin, PGA2, PGD2 and other prostaglandins

1979 • 25 citations

Tei-9063, a stable and highly specific prostacyclin analogue for the prostacyclin receptor in mastocytoma P-815 cells

1991 • 22 citations

Structure-activity relationship between prostacyclin and its platelet receptor. Correlation of structure change and the platelet activity.

1989 • 10 citations