Identification of the prostacyclin receptor by radiation inactivation.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A new and rapid colorimetric determination of acetylcholinesterase activity

1961 • 25,114 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme

1952 • 1,118 citations

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

Modulation of human platelet adenylate cyclase by prostacyclin (PGX)

1977 • 659 citations

Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets

1977 • 601 citations

Morphine receptors as regulators of adenylate cyclase activity.

1975 • 529 citations

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

1978 • 480 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Properties of Opiate-Receptor Binding in Rat Brain

1973 • 437 citations

Prostacyclin (PGX) is the endogeneous metabolite responsible for relaxation of coronary arteries induced by arachidonic acid

1977 • 412 citations

Isolation of the Insulin Receptor of Liver and Fat-Cell Membranes

1972 • 397 citations

Physical Studies of Lysozyme

1962 • 377 citations

Membrane enzyme systems molecular size determinations by radiation inactivation

1968 • 358 citations

Minitab Student Handbook.

1977 • 331 citations

Size determination of enzymes by radiation inactivation

1979 • 316 citations

Studies on the Glycosidases of Jack Bean Meal

1970 • 309 citations

Asymmetric and globular forms of acetylcholinesterase in mammals and birds.

1979 • 263 citations

Inhibition of glycosidases by aldonolactones of corresponding configuration. 2. Inhibitors of β-N-acetylglucosaminidase

1958 • 251 citations

The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK 36 374) ? Equipotent to PGI2 in vitro

1981 • 220 citations

Clinical pharmacology of prostacyclin

1981 • 211 citations

Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins.

1979 • 211 citations

Solubilization of active opiate receptors.

1980 • 199 citations

Selective Binding Site for [3H]Prostacyclin on Platelets

1979 • 199 citations

Genetic Dissection of Neural Properties using Somatic Cell Hybrids

1972 • 178 citations

Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit.

1981 • 162 citations

The Direct Action of Ionizing Radiation on Enzymes and Antigens

1955 • 129 citations

The influence of low temperature on the radiation sensitivity of enzymes.

1982 • 123 citations

The Size of Adenylate Cyclase

1974 • 122 citations

Exchange of partners in glucagon receptor-adenylate cyclase complexes. Physical evidence for the independent, mobile receptor model

1977 • 113 citations

A program for non-linear regression analysis to be used on desk-top computers

1980 • 110 citations

A regulatory component of adenylate cyclase from human erythrocyte membranes.

1980 • 109 citations

Physical and functional properties of adenylate cyclase from mature rat testis

1978 • 94 citations

PROSTACYCLIN (PGI₂) INHIBITS THE FORMATION OF PLATELET THROMBI IN ARTERIOLES AND VENULES OF THE HAMSTER CHEEK POUCH

1978 • 82 citations

Hydrodynamic properties of the regulatory component of adenylate cyclase.

1980 • 81 citations

Characterization of triton X-100-solubilized prostaglandin E binding protein of rat liver plasma membranes.

1977 • 60 citations

Size and detergent binding of adenylate cyclase from bovine cerebral cortex.

1978 • 59 citations

Structure of the turkey erythrocyte adenylate cyclase system.

1981 • 54 citations

Expression of phenotypes in hybrid somatic cells derived from the nervous system.

1975 • 53 citations

Identification and characterisation of a prostacyclin- like receptor in bovine coronary arteries using a specific and stable prostacyclin analogue, ciloprost, as radioactive ligand

1982 • 48 citations

THE BINDING OF [³H]‐PROSTACYCLIN TO MEMBRANES OF A NEURONAL SOMATIC HYBRID

1981 • 46 citations

Prostaglandin I2 receptors in a particulate fraction of platelets of various species

1980 • 45 citations

The molecular form of acetylcholinesterase as determined by irradiation inactivation (Short Communication)

1974 • 44 citations

Evidence for high affinity prostacyclin binding sites in vascular tissue: Radioligand studies with a chemically stable analogue

1983 • 43 citations

Changes in the Sensitivity of Enzymes in the Dry State to Radiation

1958 • 41 citations

Temperature Dependence of Ionizing Radiation Effect on Dry Lysozyme and Ribonuclease

1966 • 35 citations

Solubilization and conversion of hepatic adenylate cyclase to a form requiring MnATP as substrate

1979 • 34 citations

PROSTACYCLIN‐DEPENDENT ACTIVATION OF ADENYLATE CYCLASE IN A NEURONAL SOMATIC CELL HYBRID: PROSTANOID STRUCTURE‐ACTIVITY RELATIONSHIPS

1980 • 34 citations

Prostacyclin binding to guinea pig pulmonary receptors

1981 • 28 citations

Two soluble forms of guanosine 5'-(beta,gamma-imino)triphosphate and fluoride-activated adenylate cyclase.

1976 • 28 citations

Activation of guinea pig pulmonary adenylate cyclase by prostacyclin

1980 • 23 citations

Solubilization and purification of the alpha 1-adrenergic receptor using a novel affinity resin.

1982 • 23 citations

Irradiation Inactivation Analysis of Acetylcholinesterase and the Effect of Buffer Salts

1982 • 22 citations

Molecular Weight of Detergent-Solubilized Prostaglandin-F2alpha Receptor from Bovine Corpora Lutea

1980 • 14 citations

Synthesis Of [11β-3H]prostacyclin

1981 • 9 citations

Cause and treatment of atherosclerosis

1982 • 3 citations