Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis.

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor.

1989 • 1,436 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Cloning and expression of cDNA for a human thromboxane A2 receptor

1991 • 680 citations

Calcium‐activated DNA fragmentation kills immature thymocytes

1989 • 533 citations

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

1993 • 475 citations

Cellular signalling in programmed cell death (apoptosis)

1990 • 255 citations

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

1991 • 249 citations

Overview of physiological and pathophysiological effects of thromboxane A2.

1987 • 226 citations

Mouse thromboxane A2 receptor: cDNA cloning, expression and Northern blot analysis

1992 • 162 citations

Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding protein-dependent mechanism distinct from that of thrombin.

1987 • 156 citations

Purification of the thromboxane A2/prostaglandin H2 receptor from human blood platelets

1989 • 154 citations

Thromboxane-induced phosphatidate formation in human platelets. Relationship to receptor occupancy and to changes in cytosolic free calcium

1984 • 121 citations

Requirement of dendritic cells and B cells in the clonal deletion of Mls-reactive T cells in the thymus.

1991 • 113 citations

Arachidonic Acid Metabolism

1986 • 96 citations

Receptor-mediated mitogenic effect of thromboxane A2 in vascular smooth muscle cells

1990 • 93 citations

Binding of a radioiodinated 13‐azapinane thromboxane antagonist to platelets: correlation with antiaggregatory activity in different species

1986 • 73 citations

Prostaglandin-induced apoptosis of ovarian surface epithelial cells

1993 • 71 citations

In vitro and in vivo effects of new powerful thromboxane antagonists (3-alkylamino pinane derivatives).

1983 • 59 citations

Tumor Promoter-Inducible Genes Are Differentially Expressed in the Developing Mouse

1988 • 53 citations

Immunohistochemical localization of thromboxane synthase in human tissues.

1990 • 53 citations

Immunoquantitation of thromboxane synthase in human tissues.

1990 • 51 citations

Prostaglandin production by phagocytic cells of the mouse thymic reticulum in culture and its modulation by indomethacin and corticosteroids.

1985 • 48 citations

A novel integrin involved in thymocyte-thymic epithelial cell interactions.

1991 • 46 citations

Tumor promoter-inducible genes are differentially expressed in the developing mouse.

1988 • 42 citations

Identification of thromboxane A2 receptor in cultured vascular endothelial cells of rat aorta

1988 • 35 citations

Lymphocytes and arachidonic acid metabolism.

1988 • 35 citations

Production of prostaglandin E2 and prostacyclin by thymic nurse cells in culture.

1991 • 34 citations

THROMBOXANE AUGMENTATION OF ALLOREACTIVE T CELL FUNCTION

1992 • 33 citations

A murine thymic stromal cell line which may support the differentiation of CD4−8− thymocytes into CD4+8− αβ T cell receptor positive T cells

1992 • 27 citations

Localization of thromboxane synthase in human tissues by monoclonal antibody Tü 300

1992 • 24 citations

Lymphocytes and Arachidonic Acid Metabolism

1988 • 20 citations

Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to guinea-pig platelets

1986 • 17 citations