Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

1988 • 669 citations

Mammalian Tachykinin Receptors

1991 • 502 citations

Molecular characterization of a functional cDNA for rat substance P receptor

1989 • 463 citations

Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

1986 • 378 citations

Molecular Characterization of a Functional cDNA Encoding the Rat Substance P Receptor

1990 • 355 citations

Cloning and expression of a rat neuromedin K receptor cDNA.

1990 • 308 citations

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: Homophilic and heterophilic adhesion

1989 • 236 citations

Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells.

1990 • 235 citations

Chimeric muscarinic cholinergic: beta-adrenergic receptors that activate Gs in response to muscarinic agonists.

1990 • 230 citations

Thyrotropin activates both the cyclic AMP and the PIP2casades in CHO cells expressing the human cDNA of TSH receptor

1990 • 184 citations

Tissue distribution and quantitation of the mRNAs for three rat tachykinin receptors

1990 • 172 citations

Similar effects of substance P and related peptides on salivation and on phosphatidylinositol turnover in rat salivary glands.

1980 • 168 citations

Substance K : A novel mammalian tachykinin that differs from substance P in its pharmacological profile

1984 • 153 citations

A Transfected m1 Muscarinic Acetylcholine Receptor Stimulates Adenylate Cyclase via Phosphatidylinositol Hydrolysis

1989 • 146 citations

Aminoglycoside inhibition of a renal phosphatidylinositol phospholipase C.

1982 • 132 citations

STIMULATORY EFFECTS OF SUBSTANCE P ON NEURITE EXTENSION AND CYCLIC AMP LEVELS IN CULTURED NEUROBLASTOMA CELLS

1978 • 115 citations

Molecular characterization of rat substance K receptor and its mRNAs

1989 • 114 citations

The effects of substance P and carbachol on inositol tris- and tetrakisphosphate formation and cytosolic free calcium in rat parotid acinar cells. A correlation between inositol phosphate levels and calcium entry.

1987 • 105 citations

Prostaglandin E receptors in bovine adrenal medulla are coupled to adenylate cyclase via Gi and to phosphoinositide metabolism in a pertussis toxin-insensitive manner

1989 • 97 citations

Prostaglandin E receptor enhancement of catecholamine release may be mediated by phosphoinositide metabolism in bovine adrenal chromaffin cells.

1988 • 86 citations

Parallel bioassay of physalaemin and kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis

1980 • 85 citations

Different tachykinin receptor subtypes are coupled to the phosphoinositide or cyclic AMP signal transduction pathways in rat submandibular cells

1988 • 51 citations

Characterization of a tachykinin peptide NK2 receptor transfected into murine fibroblast B82 cells.

1991 • 51 citations

Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices

1985 • 44 citations

The action of substance P on contraction, inositol phospholipids and adenylate cyclase in rat small intestine

1984 • 35 citations

Molecular Characterization of Mammalian Tachykinin Receptors and a Possible Epithelial Potassium Channel

1990 • 29 citations

Effects of substance P on thyroidal cyclic AMP levels and thyroid hormone release from canine thyroid slices

1983 • 21 citations

Stimulation of cAMP formation by prostaglandin D2 in primary cultures of bovine adrenal medullary cells: identification of the responsive population as fibroblasts

1989 • 19 citations

Accelerated communication a cloned NK2 receptor mediates phosphatidylinositol hydrolysis in a transfected murine fibrolast

1990 • 13 citations