Preventing NK Cell Activation by Donor Dendritic Cells Enhances Allospecific CD4 T Cell Priming and Promotes Th Type 2 Responses to Transplantation Antigens

Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants

2002 • 3,274 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

1999 • 2,950 citations

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 • 1,271 citations

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

2000 • 1,175 citations

Dynamics of T Lymphocyte Responses: Intermediates, Effectors, and Memory Cells

2000 • 807 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection.

1990 • 561 citations

Regulation of the Natural Killer Cell Receptor Repertoire

2001 • 531 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

CD4+ but not CD8+ cells are essential for allorejection.

1996 • 303 citations

CD28 costimulation promotes the production of Th2 cytokines.

1997 • 299 citations

Dendritic and Natural Killer Cells Cooperate in the Control/Switch of Innate Immunity

2002 • 277 citations

Modulating the immune response with dendritic cells and their growth factors

2001 • 277 citations

Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation.

1997 • 273 citations

Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells.

1999 • 262 citations

Triggering of Natural Killer Cells by the Costimulatory Molecule CD80 (B7-1)

1996 • 233 citations

Murine Natural Killer Cells and Marrow Graft Rejection

1992 • 217 citations

Final Maturation of Dendritic Cells Is Associated with Impaired Responsiveness to IFN-γ and to Bacterial IL-12 Inducers: Decreased Ability of Mature Dendritic Cells to Produce IL-12 During the Interaction with Th Cells

1999 • 206 citations

Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28−/− mice

2001 • 202 citations

Paralysis of Dendritic Cell IL-12 Production by Microbial Products Prevents Infection-Induced Immunopathology

1999 • 199 citations

Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice.

1996 • 198 citations

CD4 T cell–mediated cardiac allograft rejection requires donor but not host MHC class II

2000 • 182 citations

Depletion of natural killer cells in mice by monoclonal antibody to NK-1.1. Reduction in host defense against malignancy without loss of cellular or humoral immunity.

1987 • 181 citations

Host MHC class I gene control of NK‐cell specificity in the mouse

1997 • 157 citations

Rejection of H-Y Disparate Skin Grafts by Monospecific CD4+ Th1 and Th2 Cells: No Requirement for CD8+ T Cells or B Cells

1998 • 146 citations

Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells.

1999 • 143 citations

Skin graft rejection by beta 2-microglobulin-deficient mice.

1992 • 142 citations

Cutting Edge: Blockade of the CD28/B7 Costimulatory Pathway Inhibits Intestinal Allograft Rejection Mediated by CD4+ But Not CD8+ T Cells

1999 • 125 citations

A role for eosinophils in transplant rejection

2001 • 120 citations

Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejection

1999 • 115 citations

Triggering of T cell proliferation through CD28 induces GATA‐3 and promotes T helper type 2 differentiationin vitroandin vivo

1999 • 108 citations

TRANSFUSION OF POLARIZED TH2-LIKE CELL POPULATIONS INTO SCID MOUSE CARDIAC ALLOGRAFT RECIPIENTS RESULTS IN ACUTE ALLOGRAFT REJECTION1,2

1996 • 107 citations

Flow cytometric analysis reveals the presence of asialo GM1 on the surface membrane of alloimmune cytotoxic T lymphocytes.

1986 • 100 citations

Triggering of T cell proliferation through CD28 induces GATA-3 and promotes T helper type 2 differentiationin vitro andin vivo

1999 • 95 citations

Glycolipids of the mouse peritoneal macrophage. Alterations in amount and surface exposure of specific glycolipid species occur in response to inflammation and tumoricidal activation.

1984 • 94 citations

Natural killer cells and their role in graft rejection

1998 • 90 citations

The basis for self-tolerance of natural killer cells in beta2-microglobulin- and TAP-1- mice.

1997 • 88 citations

CD4-POSITIVE HELPER T LYMPHOCYTES MEDIATE MOUSE CARDIAC ALLOGRAFT REJECTION INDEPENDENT OF DONOR ALLOANTIGEN SPECIFIC CYTOTOXIC T LYMPHOCYTES

1993 • 75 citations

Type 2 Immune Deviation Has Differential Effects on Alloreactive CD4+ and CD8+ T Cells

1998 • 71 citations

IL-5 Mediates Eosinophilic Rejection of MHC Class II-Disparate Skin Allografts in Mice

1999 • 56 citations

Lack of evidence for an active role for natural killer cells in acute rejection of organ allografts.

1985 • 48 citations

Epitope-specific binding of CD8 regulates activation of T cells and induction of cytotoxicity

1990 • 44 citations

LACK OF EVIDENCE FOR AN ACTIVE ROLE FOR NATURAL KILLER CELLS IN ACUTE REJECTION OF ORGAN ALLOGRAFTS

1985 • 43 citations

Inhibition of natural killer cell‐mediated bone marrow graft rejection by allogeneic major histocompatibility complex class I, but not class II molecules

1995 • 35 citations

Dendritic Cells Prime In Vivo Alloreactive CD4 T Lymphocytes Toward Type 2 Cytokine- and TGF-β-Producing Cells in the Absence of CD8 T Cell Activation

2000 • 35 citations

HETEROGENEITY OF T CELL CLONES SPECIFIC FOR A SINGLE INDIRECT ALLOANTIGENIC EPITOPE (I-Ab/H-2Kd54???68) THAT MEDIATE TRANSPLANT REJECTION1

2000 • 33 citations

Interleukin 4–Producing Cd4 T Cells Arise from Different Precursors Depending on the Conditions of Antigen Exposure in Vivo

2000 • 30 citations

Deleted Work

1955 • 0 citations