An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response

1997 • 1,536 citations

Origin, maturation and antigen presenting function of dendritic cells

1997 • 1,375 citations

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

1996 • 1,129 citations

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.

1994 • 866 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.

1993 • 428 citations

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

1994 • 353 citations

Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34+ bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNF-alpha.

1995 • 350 citations

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin‐10 in interferon‐γ and in interleukin‐4‐expressing cells

1994 • 305 citations

Contrasting Effects of TGF‐β1 and TNF‐α on the Development of Dendritic Cells from Progenitors in Mouse Bone Marrow

1997 • 214 citations

Dendritic cells from mouse bone marrow: In vitro differentiation using low doses of recombinant granulocyte-macrophage colony-stimulating factor

1992 • 179 citations

In vitro actions on hemopoietic cells of recombinant murine GM‐CSF purified after production in Escherichia coli: Comparison with purified native GM‐CSF

1986 • 149 citations

Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells.

1997 • 125 citations

Understanding the dendritic cell lineage through a study of cytokine receptors.

1994 • 81 citations

Isolation and Function of Human Dendritic Cells

1994 • 71 citations

An improved isolation method for murine migratory cutaneous dendritic cells

1996 • 63 citations

Isolation of Dendritic Cells

1998 • 61 citations

The Role of Cytokines in Functional Regulation and Differentiation of Dendritic Cells

1996 • 29 citations

Markers of rodent myeloid cells

1996 • 11 citations

Markers of rodent myeloid cells

1996 • 6 citations