Review

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

The 1993–94 Généthon human genetic linkage map

1994 • 1,870 citations

Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure

1995 • 964 citations

The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping

1994 • 751 citations

Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

1995 • 725 citations

Mendelian Inheritance in Man: A Catalog of Human Genes and Genetic Disorders

1998 • 693 citations

Linkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland

1992 • 571 citations

Expression cloning of a human B1 bradykinin receptor.

1994 • 455 citations

Expression cloning of a rat B2 bradykinin receptor.

1991 • 430 citations

An autosomal locus causing autoimmune disease: autoimmune polyglandular disease type I assigned to chromosome 21

1994 • 379 citations

Disease gene mapping in isolated human populations: the example of Finland.

1993 • 368 citations

Linkage disequilibrium in growing and stable populations.

1994 • 360 citations

Accelerated evolution in the reactive centre regions of serine protease inhibitors

1987 • 293 citations

Urinary Kallikrein Excretion in Hypertensive Man

1974 • 267 citations

The Finnish population structure A genetic and genealogical study

2009 • 266 citations

Hereditary diseases in Finland; rare flora in rare soul.

1973 • 255 citations

The Glandular Kallikrein Family of Enzymes: Tissue Specific Expression and Hormonal Regulation

1989 • 223 citations

Conformation of the reactive site loop of .alpha.1-proteinase inhibitor probed by limited proteolysis

1992 • 197 citations

Mapping Complex Genetic Traits in Humans: New Methods Using a Complete RFLP Linkage Map

1986 • 187 citations

Assignment of an Usher syndrome type III (USH3) gene to chromosome 3q

1995 • 184 citations

The Serpins: Evolution and Adaptation in a Family of Protease Inhibitors

1987 • 169 citations

Ein neues Kreislaufhormon und seine Wirkung

1928 • 163 citations

Mutation in gelsolin gene in Finnish hereditary amyloidosis.

1990 • 161 citations

Molecular biology of tissue kallikrein

1988 • 161 citations

Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence.

1992 • 155 citations

Localization of a gene for progressive myoclonus epilepsy to chromosome 21q22.

1991 • 154 citations

Localization of the EPM1 gene for progressive myoclonus epilepsy on chromosome 21: linkage disequilibrium allows high resolution mapping

1993 • 149 citations

Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats.

1995 • 140 citations

Aspartylglucosaminuria: cDNA encoding human aspartylglucosaminidase and the missense mutation causing the disease.

1991 • 139 citations

Convenient and quantitative determination of the frequency of a mutant allele using solid-phase minisequencing: Application to aspartylglucosaminuria in Finland

1992 • 138 citations

Human tissue kallikrein induces hypotension in transgenic mice.

1994 • 134 citations

Congenital nephrotic syndrome of the Finnish type maps to the long arm of chromosome 19.

1994 • 133 citations

Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats.

1990 • 133 citations

[Kallikreins and kinins].

1972 • 133 citations

A biometrical genome search in rats reveals the multigenic basis of blood pressure variation.

1995 • 115 citations

Evidence for a tetrahedral intermediate complex during serpin-proteinase interactions

1991 • 113 citations

Identification of a new tissue-kallikrein-binding protein

1986 • 113 citations

The locus for Meckel syndrome with multiple congenital anomalies maps to chromosome 17q21–q24

1995 • 112 citations

Defined chromosomal assignment of CLN5 demonstrates that at least four genetic loci are involved in the pathogenesis of human ceroid lipofuscinoses.

1994 • 111 citations

Random search for shared chromosomal regions in four affected individuals: the assignment of a new hereditary ataxia locus.

1995 • 108 citations

Recent developments in the understanding of bradykinin receptors

1992 • 107 citations

An initiator codon mutation in ornithine-delta-aminotransferase causing gyrate atrophy of the choroid and retina.

1988 • 101 citations

Growth hormone induces two mRNA species of the serine protease inhibitor gene family in rat liver.

1987 • 97 citations

Aberrant splicing of the CHM gene is a significant cause of choroideremia

1992 • 93 citations

Structure and Chromosomal Localization of the Gene (BDKRB2) Encoding Human Bradykinin B2 Receptor

1994 • 93 citations

Cartilage-hair hypoplasia gene assigned to chromosome 9 by linkage analysis

1993 • 91 citations

Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli.

1993 • 87 citations

The gene for a recessively inherited human childhood progressive epilepsy with mental retardation maps to the distal short arm of chromosome 8.

1994 • 86 citations

Cohen syndrome gene assigned to the long arm of chromosome 8 by linkage analysis

1994 • 85 citations

The age of human mutation: genealogical and linkage disequilibrium analysis of the CLN5 mutation in the Finnish population.

1996 • 83 citations

Inhibition of tissue kallikrein by protein C inhibitor. Evidence for identity of protein C inhibitor with the kallikrein binding protein.

1992 • 76 citations

Muscle Delivery of Human Kallikrein Gene Reduces Blood Pressure in Hypertensive Rats

1995 • 72 citations

Fine mapping of the congenital chloride diarrhea gene by linkage disequilibrium.

1995 • 70 citations

Fine mapping and haplotype analysis of the locus for congenital nephrotic syndrome on chromosome 19q13.1.

1995 • 62 citations

Refined Assignment of the Infantile Neuronal Ceroid Lipofuscinosis (INCL, CLN1) Locus at 1p32: Incorporation of Linkage Disequilibrium in Multipoint Analysis

1993 • 61 citations

High-resolution linkage-disequilibrium mapping of the cartilage-hair hypoplasia gene.

1994 • 60 citations

Human Bradykinin B2 Receptor: Nucleotide Sequence Analysis and Assignment to Chromosome 14

1993 • 59 citations

Kallikrein Multigene Families and the Regulation of Their Expression

1990 • 58 citations

Progressive Inhibition of Human Glandular (Urinary) Kallikrein by Human Serum and Identification of the Progressive Antikallikrein as α₁-Antitrypsin (α₁-Protease Inhibitor)

1981 • 55 citations

Molecular cloning and analysis of the rat kallikrein-binding protein gene

1991 • 52 citations

Urinary kallikrein and salt sensitivity in essential hypertensive males

1994 • 51 citations

Kininogens, Kinins and Kinships

1989 • 49 citations

The gene for congenital chloride diarrhea maps close to but is distinct from the gene for cystic fibrosis transmembrane conductance regulator.

1993 • 49 citations

Intramuscular Delivery of Rat Kallikrein-binding Protein Gene Reverses Hypotension in Transgenic Mice Expressing Human Tissue Kallikrein

1995 • 48 citations

The murine Spi-2 proteinase inhibitor locus: a multigene family with a hypervariable reactive site domain.

1991 • 48 citations

Hypertension in Dahl salt-sensitive rats: biochemical and immunohistochemical studies

1992 • 48 citations

A major difference of kallikrein-binding protein in spontaneously hypertensive versus normotensive rats

1988 • 44 citations

Refined localization of the gene causing X-linked juvenile retinoschisis

1991 • 41 citations

Molecular cloning and primary structure of rat .alpha.1-antitrypsin

1990 • 41 citations

Ambulatory Blood Pressure Measurement in Pregnancy: the Current State of the Art

1995 • 40 citations

Structural and expression analyses of normal and mutant mRNA encoding glycine decarboxylase: Three-base deletion in mRNA causes nonketotic hyperglycinemia

1991 • 40 citations

Identification of a novel mutation causing aspartylglucosaminuria reveals a mutation hotspot region in the aspartylglucosaminidase gene

1995 • 39 citations

The molecular biology of the kallikrein???kinin system: III. The human kallikrein gene family and kallikrein substrate

1993 • 36 citations

Selective intestinal malabsorption of vitamin B12 displays recessive mendelian inheritance: assignment of a locus to chromosome 10 by linkage.

1995 • 36 citations

Molecular Cloning, Sequence Analysis, and Chromosomal Localization of the Human Protease Inhibitor 4 (Kallistatin) Gene (PI4)

1994 • 34 citations

Cornea plana congenita gene assigned to the long arm of chromosome 12 by linkage analysis

1995 • 33 citations

Differential interactions of human kallikrein-binding protein and α1-antitrypsin with human tissue kallikrein

1990 • 33 citations

The genetic locus for free sialic acid storage disease maps to the long arm of chromosome 6.

1994 • 32 citations

Activation of serpins and their cognate proteases in muscle after crush injury

1994 • 31 citations

Inhibition of rat tissue kallikrein gene family members by rat kallikrein‐binding protein and α1‐proteinase inhibitor

1992 • 29 citations

The molecular biology of the kallikrein???kinin system: II. The rat gene family

1993 • 28 citations

The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction

1991 • 27 citations

Primary structure and assignment to chromosome 6 of three related rat genes encoding liver serine protease inhibitors

1990 • 26 citations

Haplotype analysis in gelsoiin-related amyloidosis reveals independent origin of identical mutation (G654A) of gelsolin in Finland and Japan

1995 • 24 citations

Specific identification of tissue kallikrein in exocrine tissues and in cell-free translation products with monoclonal antibodies

1985 • 24 citations

X‐linked retinoschisis is closely linked to DXS41 and DXS16 but not DXS85

1987 • 24 citations

Linkage Disequilibrium Utilized to Establish a Refined Genetic Position of the Salla Disease Locus on 6q14-q15

1995 • 22 citations

Compared Effects of a Low and a High Sodium Diet on the Renal and Urinary Concentration and Activity of Kallikrein in Normal Rats

1987 • 21 citations

Gene mapping in experimental hypertension.

1992 • 20 citations

Chromosomal mapping of human kininogen gene (KNG) to 3q26→qter

1992 • 19 citations

Salt and Hypertension: Water‐Sodium Handling in Essential Hypertension

1993 • 19 citations

Linkage Disequilibrium Mapping of the Cornea Plana Congenita Gene CNA2

1995 • 18 citations

Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene

1991 • 17 citations

Receptor Antagonists of Bradykinin: A New Tool to Study the Cardiovascular Effects of Endogenous Kinins

1993 • 8 citations