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1966 • 26,261 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

1981 • 1,881 citations

Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction.

1990 • 1,484 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

Absolute mRNA quantification using the polymerase chain reaction (PCR). A novel approach by aPCR aidedtranscipttitration assay (PATTY)

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1989 • 596 citations

A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E

1990 • 402 citations

Optimal conditions for directly sequencing double-stranded PCR products with Sequenase

1990 • 357 citations

Oligosaccharides in urine of patients with glycoprotein storage diseases

1975 • 182 citations

Aspartylglucosaminuria: cDNA encoding human aspartylglucosaminidase and the missense mutation causing the disease.

1991 • 139 citations

Quantification of polymerase chain reaction products by affinity-based hybrid collection

1988 • 128 citations

Enzymatic cleavage of glycopeptides

1966 • 100 citations

Current trends in mapping human genes

1991 • 62 citations

Screening for Defined Cystic Fibrosis Mutations by Solid-Phase Minisequencing

1992 • 44 citations

Enzymatic Diagnosis and Carrier Detection of Aspartylglucosaminuria Using Blood Samples

1976 • 40 citations

In vitro mutagenesis helps to unravel the biological consequences of aspartylglucosaminuria mutation

1991 • 39 citations

Biotinylation of Oligonucleotides Using a Water Soluble Biotin Ester

1990 • 35 citations