An initiator codon mutation in ornithine-delta-aminotransferase causing gyrate atrophy of the choroid and retina.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

1987 • 1,074 citations

Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences

1986 • 766 citations

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. 1985.

1992 • 740 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.

1983 • 568 citations

Detection of Single Base Substitutions by Ribonuclease Cleavage at Mismatches in RNA:DNA Duplexes

1985 • 538 citations

Nucleotide sequence of a full-length complementary DNA clone and amino acid sequence of human phenylalanine hydroxylase

1985 • 325 citations

A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.

1985 • 320 citations

The Lebanese allele at the low density lipoprotein receptor locus. Nonsense mutation produces truncated receptor that is retained in endoplasmic reticulum.

1987 • 282 citations

The Molecular Basis of the Sparse Fur Mouse Mutation

1987 • 253 citations

Identification and Localization of Mutations at the Lesch-Nyhan Locus by Ribonuclease A Cleavage

1987 • 149 citations

Initiation codon mutation as a cause of alpha thalassemia.

1984 • 130 citations

Saccharomyces cerevisiae ribosomes recognize non-AUG initiation codons.

1984 • 110 citations

Molecular cloning of human ornithine aminotransferase mRNA.

1986 • 94 citations

An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype.

1987 • 77 citations

Segment-specific mutagenesis of the regulatory region in the Escherichia coli galactose operon: isolation of mutations reducing the initiation of transcription and translation

1983 • 70 citations

Investigation of Gyrate Atrophy Using a cDNA Clone for Human Ornithine Aminotransferase

1986 • 45 citations

Genetic diseases in Lebanon

1980 • 41 citations

Molecular genetics of hemophilia A in man (factor VIII deficiency).

1987 • 39 citations

The primary structure of ornithine aminotransferase

1986 • 35 citations

Saccharomyces cerevisiae Ribosomes Recognize Non-Aug Initiation Codons

1984 • 30 citations

Clinical, biochemical, and therapeutic aspects of gyrate atrophy

1987 • 23 citations

The varieties of mutation.

1988 • 6 citations

Inborn errors of metabolism in the molecular age.

1988 • 3 citations

The varieties of mutation.

1988 • 1 citations