Potential Diagnostic Markers for Alzheimer’s Disease

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Observations on the brains of demented old people

1970 • 2,066 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

1986 • 1,387 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

1988 • 1,186 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

1988 • 1,073 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

1988 • 920 citations

Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 • 899 citations

Ubiquitin Is a Component of Paired Helical Filaments in Alzheimer's Disease

1987 • 834 citations

Observations on the brains of non-demented old people

1968 • 656 citations

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.

1987 • 606 citations

A Neuronal Antigen in the Brains of Alzheimer Patients

1986 • 577 citations

Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related.

1985 • 431 citations

Senile Dementia of the Alzheimer Type Without Neocortical Neurofibrillary Tangles

1987 • 269 citations

Neocortical morphometry, lesion counts, and choline acetyltransferase levels in the age spectrum of Alzheimer's disease

1988 • 192 citations

Alz‐50 Antibody recognizes alzheimer‐related neuronal changes

1988 • 177 citations

Alzheimer‐related neuronal protein A68: Specificity and distribution

1987 • 176 citations

Phosphorylated Neurofilament Antigens in Neurofibrillary Tangles in Alzheimerʼs Disease

1986 • 158 citations

Alzheimer's neurofibrillary tangles contain unique epitopes and epitopes in common with the heat-stable microtubule associated proteins tau and MAP2.

1987 • 147 citations

Cytoskeletal protein abnormalities in neurodegenerative diseases

1986 • 137 citations

Gracile tract degeneration in patients with sensory neuropathy and AIDS

1988 • 112 citations

Reexpression of a developmentally regulated antigen in Down syndrome and Alzheimer disease.

1988 • 103 citations

Microtubule-associated protein tau (? ) is a major antigenic component of paired helical filaments in Alzheimer disease

1987 • 99 citations

Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy

1988 • 74 citations

Paired Helical Filaments (PHF): Update 1988

1988 • 1 citations