Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

1986 • 1,709 citations

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

1986 • 1,387 citations

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

1988 • 1,073 citations

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

1985 • 1,025 citations

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

1963 • 956 citations

Ubiquitin Is a Component of Paired Helical Filaments in Alzheimer's Disease

1987 • 834 citations

Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

1986 • 729 citations

The Primary Structure and Heterogeneity of Tau Protein from Mouse Brain

1988 • 671 citations

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants

1982 • 541 citations

ALZHEIMER’S DISEASE —AN ELECTRON MICROSCOPICAL STUDY

1964 • 440 citations

Use of colloidal gold particles in double-labeling immunoelectron microscopy of ultrathin frozen tissue sections.

1981 • 387 citations

One of the Antigenic Determinants of Paired Helical Filaments Is Related to Tau Protein1

1986 • 336 citations

Subunit structure of paired helical filaments in Alzheimer's disease.

1985 • 224 citations

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components.

1985 • 220 citations

Image reconstruction of the Alzheimer paired helical filament.

1985 • 184 citations

Alzheimer's paired helical filaments share epitopes with neurofilament side arms.

1986 • 132 citations

Immunostaining of neurofibrillary tangles in Alzheimer's senile dementia with a neurofilament antiserum

1982 • 97 citations

Immunocytochemical studies of neurofibrillary tangles.

1981 • 78 citations

In Vitro Conditions for the Self-Polymerization of the Microtubule-Associated Protein, Tau Factor

1987 • 37 citations

SUBUNIT STRUCTURE OF THE ALZHEIMER TANGLE

1986 • 34 citations