Multipotent Stem Cells in the Adult Central Nervous System

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain

1999 • 3,822 citations

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

Long-Distance Neuronal Migration in the Adult Mammalian Brain

1994 • 2,291 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

1997 • 1,880 citations

Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

1999 • 1,872 citations

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

1993 • 1,799 citations

Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt

1990 • 1,793 citations

Stem Cells

2000 • 1,783 citations

Stem Cells in the Central Nervous System

1997 • 1,483 citations

Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb

1969 • 1,471 citations

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

1997 • 1,468 citations

Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light Radioautographs

1977 • 1,438 citations

Turning Brain into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells in Vivo

1999 • 1,437 citations

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

1994 • 1,400 citations

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress

1998 • 1,386 citations

Clonal and Population Analyses Demonstrate That an EGF-Responsive Mammalian Embryonic CNS Precursor Is a Stem Cell

1996 • 1,366 citations

Neuron‐glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electonmicroscopic study in Macacus rhesus

1971 • 1,334 citations

Chain Migration of Neuronal Precursors

1996 • 1,312 citations

Neurogenesis in the Neocortex of Adult Primates

1999 • 1,268 citations

Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat

1993 • 1,215 citations

Multipotent CNS Stem Cells Are Present in the Adult Mammalian Spinal Cord and Ventricular Neuroaxis

1996 • 1,209 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

1998 • 1,135 citations

The Adult Rat Hippocampus Contains Primordial Neural Stem Cells

1997 • 1,080 citations

Regulatory Mechanisms in Stem Cell Biology

1997 • 1,060 citations

Smell and Taste in Health and Disease

1992 • 1,035 citations

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

1996 • 1,027 citations

Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus

1994 • 986 citations

Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons

1979 • 983 citations

Fibroblast Growth Factor-2 Activates a Latent Neurogenic Program in Neural Stem Cells from Diverse Regions of the Adult CNS

1999 • 916 citations

Development of the Cerebellar System: In Relation to Its Evolution, Structure, and Functions

1996 • 864 citations

Isolation, Characterization, and use of Stem Cells from the CNS

1995 • 819 citations

Hippocampal neurogenesis in adult Old World primates

1999 • 804 citations

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain

1996 • 757 citations

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus

1995 • 738 citations

Multipotent progenitor cells in the adult dentate gyrus

1998 • 722 citations

FGF-2-Responsive Neuronal Progenitors Reside in Proliferative and Quiescent Regions of the Adult Rodent Brain

1995 • 691 citations

bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells

1993 • 651 citations

Adrenal hormones suppress cell division in the adult rat dentate gyrus

1992 • 638 citations

Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo

1996 • 626 citations

Neurons in the Rat Dentate Gyrus Granular Layer Substantially Increase During Juvenile and Adult Life

1982 • 589 citations

Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination

1999 • 536 citations

De novo generation of neuronal cells from the adult mouse brain.

1992 • 535 citations

Is there a neural stem cell in the mammalian forebrain?

1996 • 535 citations

Epidermal and Fibroblast Growth Factors Behave as Mitogenic Regulators for a Single Multipotent Stem Cell-Like Population from the Subventricular Region of the Adult Mouse Forebrain

1999 • 534 citations

Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics

1999 • 530 citations

Intraventricular Administration of BDNF Increases the Number of Newly Generated Neurons in the Adult Olfactory Bulb

1998 • 528 citations

Multipotent Stem/Progenitor Cells with Similar Properties Arise from Two Neurogenic Regions of Adult Human Brain

1999 • 527 citations

The hippocampus as an associator of discontiguous events

1998 • 526 citations

Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat

1993 • 465 citations

FGF2 Concentration Regulates the Generation of Neurons and Glia from Multipotent Cortical Stem Cells

1997 • 455 citations

Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus

1984 • 453 citations

The subependymal layer of the mouse brain and its cell production as shown by radioautography after thymidine‐H³ injection

1961 • 446 citations

Stem cells in the adult mammalian central nervous system

1999 • 439 citations

Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections

1988 • 429 citations

Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation

1993 • 381 citations

Interaction between astrocytes and adult subventricular zone precursors stimulates neurogenesis

1999 • 358 citations

The Role of Polysialic Acid in Migration of Olfactory Bulb Interneuron Precursors in the Subventricular Zone

1996 • 357 citations

Olfactory Recognition: A Simple Memory System

1990 • 349 citations

Response Diversity and the Timing of Progenitor Cell Maturation Are Regulated by Developmental Changes in EGFR Expression in the Cortex

1997 • 329 citations

Mapping of the distribution of polysialylated neural cell adhesion molecule throughout the central nervous system of the adult rat: An immunohistochemical study

1992 • 309 citations

In vitro Neuronal Production and Differentiation by Precursor Cells Derived from the Adult Human Forebrain

1994 • 304 citations

In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain

1998 • 304 citations

Consequences of Neural Cell Adhesion Molecule Deficiency on Cell Migration in the Rostral Migratory Stream of the Mouse

2000 • 297 citations

Widespread Integration and Survival of Adult-Derived Neural Progenitor Cells in the Developing Optic Retina

1998 • 296 citations

Autoradiographic study of histogenesis in the mouse olfactory bulb. II. Cell proliferation and migration

1968 • 296 citations

Distribution of spatial and nonspatial information in dorsal hippocampus

1999 • 295 citations

Fibroblast Growth Factor 2 (FGF-2) Promotes Acquisition of Epidermal Growth Factor (EGF) Responsiveness in Mouse Striatal Precursor Cells: Identification of Neural Precursors Responding to both EGF and FGF-2

1998 • 292 citations

Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis

1998 • 285 citations

FGF-2 Is Sufficient to Isolate Progenitors Found in the Adult Mammalian Spinal Cord

1997 • 278 citations

Multipotent and restricted precursors in the central nervous system

1999 • 269 citations

Pre-oligodendrocytes from adult human CNS

1992 • 267 citations

Olfactory bulb ensheathing glia: A unique cell type with axonal growth‐promoting properties

1995 • 255 citations

Subventricular zone‐olfactory bulb migratory pathway in the adult mouse: Cellular composition and specificity as determined by heterochronic and heterotopic transplantation

1996 • 248 citations

Glial Tubes in the Rostral Migratory Stream of the Adult Rat

1997 • 246 citations

Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF

1995 • 238 citations

Expression of polysialylated neural cell adhesion molecule by proliferating cells in the subependymal layer of the adult rat, in its rostral extension and in the olfactory bulb

1994 • 215 citations

Birth, migration, incorporation, and death of vocal control neurons in adult songbirds

1997 • 213 citations

The subependymal layer in rodents: a site of structural plasticity and cell migration in the adult mammalian brain

1999 • 212 citations

Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus

2000 • 210 citations

Young neurons from the adult subependymal zone proliferate and migrate along an astrocyte, extracellular matrix-rich pathway

1996 • 178 citations

Stem cells and cellular pedigrees – a conceptual introduction

1997 • 167 citations

The neuronal stem cell of the olfactory epithelium

1998 • 165 citations

Discussion point Stem cells of the central nervous system

1998 • 156 citations

Stem cells in the developing and adult nervous system

1998 • 155 citations

Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS

1995 • 143 citations

Discussion point stem cells and neurogenesis in the adult brain

1998 • 140 citations

Marrow-mindedness: a perspective on neuropoiesis

1999 • 109 citations

Isolation and Developmental Characterization of Cerebral Cortical Multipotent Progenitors

1998 • 101 citations

Neural progenitors and stem cells: mechanisms of progenitor heterogeneity

1998 • 96 citations

The search for neural progenitor cells: prospects for the therapy of neurodegenerative disease

1999 • 80 citations

Newly-generated cells from the rostral migratory stream in the accessory olfactory bulb of the adult rat

1997 • 76 citations

Central nervous system stem cells in the embryo and adult

1998 • 71 citations

CNS stem cells: Where's the biology (a.k.a. beef)?

1998 • 70 citations

Migrational analysis of the constitutively proliferating subependyma population in adult mouse forebrain

1999 • 63 citations

Origins, functions, and potential of adult neural stem cells

1999 • 52 citations

CNS development: The obscure origins of adult stem cells

1999 • 24 citations