Stem cells in the adult mammalian central nervous system

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Long-Distance Neuronal Migration in the Adult Mammalian Brain

1994 • 2,291 citations

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

1997 • 1,880 citations

Cellular Composition and Three-Dimensional Organization of the Subventricular Germinal Zone in the Adult Mammalian Brain

1997 • 1,878 citations

Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

1999 • 1,872 citations

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

1993 • 1,799 citations

Neurogenesis in the Adult Rat: Electron Microscopic Analysis of Light Radioautographs

1977 • 1,438 citations

Turning Brain into Blood: A Hematopoietic Fate Adopted by Adult Neural Stem Cells in Vivo

1999 • 1,437 citations

Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells

1994 • 1,400 citations

Chain Migration of Neuronal Precursors

1996 • 1,312 citations

Multipotent CNS Stem Cells Are Present in the Adult Mammalian Spinal Cord and Ventricular Neuroaxis

1996 • 1,209 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.

1996 • 1,164 citations

Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

1998 • 1,135 citations

The Adult Rat Hippocampus Contains Primordial Neural Stem Cells

1997 • 1,080 citations

GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis

1995 • 1,073 citations

Regulatory Mechanisms in Stem Cell Biology

1997 • 1,060 citations

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor

1996 • 1,027 citations

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

1995 • 1,014 citations

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

1992 • 928 citations

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain

1996 • 757 citations

Network of tangential pathways for neuronal migration in adult mammalian brain

1996 • 720 citations

FGF-2-Responsive Neuronal Progenitors Reside in Proliferative and Quiescent Regions of the Adult Rodent Brain

1995 • 691 citations

Notch Receptor Activation Inhibits Oligodendrocyte Differentiation

1998 • 675 citations

Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo

1996 • 626 citations

Conservation of the Notch signalling pathway in mammalian neurogenesis

1997 • 617 citations

Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2

1998 • 593 citations

Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats

1998 • 539 citations

Stem cells: the generation and maintenance of cellular diversity

1989 • 504 citations

3H-thymidine-radiographic studies of neurogenesis in the rat olfactory bulb

1983 • 501 citations

Seasonal recruitment of hippocampal neurons in adult free-ranging black-capped chickadees.

1994 • 488 citations

Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo

1998 • 484 citations

Identification of an adult-specific glial progenitor cell

1989 • 476 citations

Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus

1984 • 453 citations

Long-Term Survival of Human Central Nervous System Progenitor Cells Transplanted into a Rat Model of Parkinson's Disease

1997 • 449 citations

Transforming Growth Factor-α Null and Senescent Mice Show Decreased Neural Progenitor Cell Proliferation in the Forebrain Subependyma

1997 • 442 citations

Developmental neurobiology

1971 • 396 citations

The Ins and Outs of Notch Signaling

1997 • 386 citations

Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway

1997 • 381 citations

Response Diversity and the Timing of Progenitor Cell Maturation Are Regulated by Developmental Changes in EGFR Expression in the Cortex

1997 • 329 citations

In vitro Neuronal Production and Differentiation by Precursor Cells Derived from the Adult Human Forebrain

1994 • 304 citations

In vivo clonal analyses reveal the properties of endogenous neural stem cell proliferation in the adult mammalian forebrain

1998 • 304 citations

Fibroblast Growth Factor 2 (FGF-2) Promotes Acquisition of Epidermal Growth Factor (EGF) Responsiveness in Mouse Striatal Precursor Cells: Identification of Neural Precursors Responding to both EGF and FGF-2

1998 • 292 citations

Birth of Projection Neurons in Adult Avian Brain May Be Related to Perceptual or Motor Learning

1990 • 283 citations

FGF-2 Is Sufficient to Isolate Progenitors Found in the Adult Mammalian Spinal Cord

1997 • 278 citations

Neuronal Replacement in Adulthood

1985 • 278 citations

Development and differentiation of glial precursor cells in the rat cerebellum

1993 • 276 citations

Neural precursor cell chain migration and division are regulated through different β1 integrins

1998 • 265 citations

Expression of Neural RNA-Binding Proteins in the Postnatal CNS: Implications of Their Roles in Neuronal and Glial Cell Development

1997 • 256 citations

Cooperation between PDGF and FGF converts slowly dividing O-2Aadult progenitor cells to rapidly dividing cells with characteristics of O-2Aperinatal progenitor cells.

1992 • 230 citations

Reply to “Survival of expanded dopaminergic precursors is critical for clinical trials”

1998 • 218 citations

Purification and Characterization of Adult Oligodendrocyte Precursor Cells from the Rat Optic Nerve

1998 • 217 citations

Regulation of Neuronal Birth, Migration and Death in the Rat Dentate Gyrus

1996 • 195 citations

A PDGF-Regulated Immediate Early Gene Response Initiates Neuronal Differentiation in Ventricular Zone Progenitor Cells

1997 • 185 citations

Neuronal Progenitor Cells Derived from the Anterior Subventricular Zone of the Neonatal Rat Forebrain Continue to Proliferatein Vitroand Express a Neuronal Phenotype

1997 • 181 citations

Immortalizing oncogenes subvert the establishment of granule cell identity in developing cerebellum

1994 • 149 citations

In vitro analysis of the origin and maintenance of O-2Aadult progenitor cells.

1992 • 144 citations

Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS

1995 • 143 citations

Incorporation and Glial Differentiation of Mouse EGF-Responsive Neural Progenitor Cells after Transplantation into the Embryonic Rat Brain

1998 • 129 citations

Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells derived from adult rat spinal cord: In vitro characteristics and response to PDGF, bFGF and NT-3

1996 • 103 citations

Postnatal mouse subventricular zone neuronal precursors can migrate and differentiate within multiple levels of the developing neuraxis

1997 • 99 citations

Isolation of neuronal precursors by sorting embryonic forebrain transfected with GFP regulated by the Tα1 tubulin promoter

1998 • 85 citations

Cellular Localization of Transforming Growth Factor-? mRNA in Rat Forebrain

1993 • 83 citations

A goldfishNotch-3 homologue is expressed in neurogenic regions of embryonic, adult, and regenerating brain and retina

1997 • 58 citations

Hope for a new neurology

1985 • 30 citations

Progenitor cells in the adult zebrafish nervous system express a Brn-1-related POU gene, tai-ji1`Tai-ji' is a Chinese philosophical term meaning `the source of generation and change'.1

1998 • 28 citations

Ex vivo gene delivery of platelet-derived growth factor increases 0-2A progenitors in adult rat spinal cord.

1996 • 24 citations

The future belongs to the bioentrepreneur

1998 • 8 citations