Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Interleukin-6 and Its Receptor: A Paradigm for Cytokines

1992 • 889 citations

Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6

1989 • 775 citations

Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition.

1990 • 639 citations

Long-term culture of human bone marrow cells.

1980 • 624 citations

IgG1 plasmacytosis in interleukin 6 transgenic mice.

1989 • 597 citations

Role of beta 1 and beta 2 integrins in the adhesion of human CD34hi stem cells to bone marrow stroma.

1992 • 388 citations

Induction of Plasma-Cell Neoplasms in Strain BALB/c Mice with Mineral Oil and Mineral Oil Adjuvants

1962 • 311 citations

Direct contact between human primitive hematopoietic progenitors and bone marrow stroma is not required for long-term in vitro hematopoiesis

1992 • 245 citations

Response patterns of purified myeloma cells to hematopoietic growth factors

1989 • 231 citations

Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen

1993 • 230 citations

Regulatory properties of LFA-1 α and β chains in human T-lymphocyte activation

1988 • 225 citations

'Role of bone marrow stromal cells in the growth of human multiple myeloma

1991 • 223 citations

Interleukin 7 production and function in stromal cell-dependent B cell development.

1989 • 221 citations

Interleukin 3 and interleukin 6 synergistically promote the proliferation and differentiation of malignant plasma cell precursors in multiple myeloma.

1989 • 163 citations

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

1989 • 158 citations

Production of cytokines by bone marrow cells obtained from patients with multiple myeloma

1989 • 156 citations

Characterization of adhesion molecules on human myeloma cell lines

1992 • 150 citations

Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein.

1992 • 143 citations

Interleukin-1 accelerates autocrine growth of myeloma cells through interleukin-6 in human myeloma

1989 • 141 citations

Biologic significance of constitutive and subliminal growth factor production by bone marrow stroma

1992 • 139 citations

VLA-4-fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion.

1992 • 135 citations

Selective expression of CD45 isoforms defines CALLA+ monoclonal B- lineage cells in peripheral blood from myeloma patients as late stage B cells

1991 • 129 citations

Granulocyte-macrophage colony-stimulating factor synergizes with interleukin-6 in supporting the proliferation of human myeloma cells [see comments]

1990 • 125 citations

Interleukin 6 (IL‐6) and its receptor: Their role in plasma cell neoplasias

1991 • 122 citations

Bone marrow stromal fibroblasts secrete interleukin-6 and granulocyte- macrophage colony-stimulating factor in the absence of inflammatory stimulation: demonstration by serum-free bioassay, enzyme-linked immunosorbent assay, and reverse transcriptase polymerase chain reaction

1992 • 100 citations

Lymphocyte function-associated antigen-1 expression on plasma cells correlates with tumor growth in multiple myeloma

1992 • 88 citations

Role of interleukin-6 in the proliferation of human multiple myeloma cell lines OCI-My 1 to 7 established from patients with advanced stage of the disease

1991 • 85 citations

Effects of interleukin-4 on the in vitro growth of human lymphoid and plasma cell neoplasms

1990 • 85 citations

Surface antigen expression of human neoplastic plasma cells includes molecules associated with lymphocyte recirculation and adhesion

1991 • 84 citations

Follicular non-Hodgkin's lymphoma cell adhesion to normal germinal centers and neoplastic follicles involves very late antigen-4 and vascular cell adhesion molecule-1

1992 • 74 citations

Role of interleukin 6 in the growth of myelomaderived cell lines

1992 • 74 citations

Bone marrow stromal cell regulation of B-lymphopoiesis. I. The role of macrophages, IL-1, and IL-4 in pre-B cell maturation.

1988 • 67 citations

Interleukin-4 inhibits growth of multiple myelomas by suppressing interleukin-6 expression.

1991 • 65 citations

Idiotype-bearing Lymphoid Cells in Plasma Cell Neoplasia

1982 • 65 citations

Interleukin-11 promotes accessory cell-dependent B-cell differentiation in humans

1992 • 63 citations

Two new IgA1-kappa plasma cell leukaemia cell lines (JJN-1 & JJN-2) which proliferate in response to B cell stimulatory factor 2.

1989 • 60 citations

Pre-B cells in peripheral blood of multiple myeloma patients

1985 • 59 citations

Human marrow stromal cells: response to interleukin-6 (IL-6) and control of IL-6 expression

1989 • 55 citations

Lack of a role of interleukin 11 in the growth of multiple myeloma

1992 • 43 citations

Regulation of c-jun gene expression in human T lymphocytes

1993 • 21 citations

Establishment of a variety of human bone marrow stromal cell lines by the recombinant SV40‐adenovirus vector

1991 • 20 citations

Endothelial cell receptors on leukemic plasma cells

1989 • 13 citations