Response patterns of purified myeloma cells to hematopoietic growth factors

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Characterization of a human B lymphocyte-specific antigen.

1980 • 1,098 citations

A monoclonal antibody to human acute lymphoblastic leukaemia antigen

1980 • 748 citations

Expression of human B cell-associated antigens on leukemias and lymphomas: a model of human B cell differentiation

1984 • 714 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

Antigens on human monocytes identified by monoclonal antibodies.

1981 • 583 citations

B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes.

1983 • 517 citations

Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities.

1986 • 514 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Expression of interleukin 2 receptors on activated human B cells.

1984 • 488 citations

A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells

1984 • 420 citations

A unique cell surface antigen identifying lymphoid malignancies of B cell origin.

1981 • 409 citations

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II

1986 • 405 citations

Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from an IgE myeloma patient.

1970 • 375 citations

Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells

1984 • 375 citations

Characterization of a human B cell-specific antigen (B2) distinct from B1.

1981 • 363 citations

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells.

1987 • 357 citations

Expression of Tac antigen on activated normal human B cells.

1984 • 355 citations

Hairy cell leukemia: a tumor of pre-plasma cells

1985 • 329 citations

Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins.

1988 • 327 citations

Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1988 • 296 citations

Generation of monoclonal antibodies to a human natural killer clone. Characterization of two natural killer-associated antigens, NKH1A and NKH2, expressed on subsets of large granular lymphocytes.

1985 • 279 citations

Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.

1979 • 255 citations

T cell-replacing factor- (TRF) induced IgG secretion in a human B blastoid cell line and demonstration of acceptors for TRF.

1981 • 242 citations

Effects of B cell stimulatory factor-1/interleukin 4 on hematopoietic progenitor cells

1987 • 213 citations

B cell growth-promoting activity of recombinant human interleukin 4.

1987 • 211 citations

Antigens on human plasma cells identified by monoclonal antibodies.

1983 • 207 citations

Cloning of cDNA for human T-cell replacing factor (interieukin-5) and comparison with the murine homologue

1986 • 205 citations

Human β ₂ Interferon and B-Cell Differentiation Factor BSF-2 Are Identical

1987 • 204 citations

Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays.

1983 • 204 citations

Identification of malignant plasma cell precursors in the bone marrow of multiple myeloma.

1985 • 160 citations

Proliferative responses of normal human B lymphocytes. Development of an assay system for human B cell growth factor (BCGF).

1982 • 142 citations

Detection and functional studies of p60-65 (Tac antigen) on activated human B cells.

1984 • 136 citations

Phenotypic heterogeneity in aneuploid multiple myeloma indicates pre-B cell involvement

1988 • 111 citations

The Monoclonal Nature of Lymphocytes in Multiple Myeloma

1975 • 107 citations

Delineation of a novel pre-B cell component in plasma cell myeloma: immunochemical, immunophenotypic, genotypic, cytologic, cell culture, and kinetic features

1987 • 105 citations

Induction of human B cell antigens in non-T cell acute lymphoblastic leukemia.

1982 • 103 citations

BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12).

1985 • 100 citations

B cell growth factor activity of interferon-gamma. Recombinant human interferon-gamma promotes proliferation of anti-mu-activated human B lymphocytes.

1986 • 97 citations

Idiotype‐bearing and antigen‐binding receptors produced by blood T lymphocytes in a case of human myeloma

1977 • 96 citations

Structural and functional characterization of IL 2 receptors on activated human B cells.

1985 • 92 citations

Purification to homogeneity of a high molecular weight human B cell growth factor; demonstration of specific binding to activated B cells; and development of a monoclonal antibody to the factor.

1985 • 88 citations

Soluble factor activation of human B lymphocytes

1981 • 80 citations

Human IgE antibody synthesis in vitro: stimulation of IgE responses by pokeweed mitogen and selective inhibition of such responses by human suppressive factor of allergy (SFA).

1981 • 77 citations

Human interferon-gamma acts as a B cell growth factor in the anti-IgM antibody co-stimulatory assay but has no direct B cell differentiation activity.

1986 • 77 citations

Effect of B cell differentiation factor (BCDF) on biosynthesis and secretion of immunoglobulin molecules in human B cell lines.

1985 • 75 citations

B5, a new B cell-restricted activation antigen.

1985 • 73 citations

Immortalization of BGDF (BCGF II)- and BCDF-producing T cells by human T cell leukemia virus (HTLV) and characterization of human BGDF (BCGF II).

1985 • 73 citations

Role of BCGFII in the differentiation to antibody secretion normal and tumor B cells.

1985 • 71 citations

Idiotype-bearing Lymphoid Cells in Plasma Cell Neoplasia

1982 • 65 citations

Purification of common acute lymphoblastic leukemia antigen positive cells from normal human bone marrow

1984 • 64 citations

Shared Idiotypes on Human Peripheral Blood B and T Lymphocytes

1979 • 63 citations

Decrease in BSF-2/IL-6 response in advanced cases of multiple myeloma

1988 • 59 citations

Clonal differences in response to T cell replacing factor (TRF) for IgM secretion and TRF receptors in a human B lymphoblast cell line

1983 • 52 citations

Growth factor-mediated tumor cell proliferation in hairy cell leukemia.

1985 • 50 citations

IgD on cell membranes of human lymphoid cell lines with multiple immunoglobulin classes

1974 • 44 citations

Regulation of human B lymphopoiesis: effect of a urinary activity associated with cyclic neutropenia.

1985 • 43 citations

Growth factor-mediated proliferation in B cell non-Hodgkin's lymphomas

1985 • 41 citations

Low molecular weight B cell growth factor induces proliferation of human B cell precursor acute lymphoblastic leukemias

1987 • 41 citations

A case of human B cell leukemia that implicates an autocrine mechanism in the abnormal growth of Leu 1 B cells.

1986 • 34 citations

Sequential synergistic effect of interleukin 2 and interferon-gamma on the differentiation of a Tac-antigen-positive B cell line.

1986 • 34 citations

Identification and characterization of a B cell growth inhibitory factor (BIF) on BCGF-dependent B cell proliferation.

1985 • 23 citations

Isolation and characterization of human B lymphocyte enriched populations. I. Purification of B cells by immune rosette depletion

1983 • 21 citations

Dual fluorochrome analysis of human B lymphocytes: phenotypic examination of resting, anti-immunoglobulin stimulated, and in vivo activated B cells.

1986 • 20 citations

Identification and characterization of a B cell activation factor (BCAF) produced by a human T cell line.

1986 • 20 citations

The response of selected human B cell lines to B cell growth and differentiation factors

1987 • 19 citations

Physicochemical and functional properties of murine B cell-derived B cell growth factor II (WEHI-231-BCGF-II).

1985 • 16 citations