Production of cytokines by bone marrow cells obtained from patients with multiple myeloma

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

An interleukin 1 like factor stimulates bone resorption in vitro

1983 • 1,017 citations

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1984 • 638 citations

Smoldering Multiple Myeloma

1980 • 446 citations

Impaired Synthesis of Polyclonal (Non-Paraprotein) Immunoglobulins by Circulating Lymphocytes from Patients with Multiple Myeloma

1975 • 430 citations

Interleukin 6 is involved in interleukin 1‐induced activities

1988 • 422 citations

Production of Lymphotoxin, a Bone-Resorbing Cytokine, by Cultured Human Myeloma Cells

1987 • 386 citations

Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria.

1985 • 382 citations

Characterization of lymphocyte-activating factor (LAF) produced by the macrophage cell line, P388D1. I. Enhancement of LAF production by activated T lymphocytes.

1978 • 379 citations

New Concepts on the Pathogenesis of Fever

1988 • 373 citations

Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis.

1987 • 303 citations

Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization.

1984 • 284 citations

Recombinant human interleukin 1 alpha: purification and biological characterization.

1986 • 216 citations

Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors

1987 • 210 citations

Evidence for peripheral blood B lymphocyte but not T lymphocyte involvement in multiple myeloma

1987 • 146 citations

Relation of Osteoclast Activating Factor Production to Extent of Bone Disease in Multiple Myeloma

1981 • 122 citations

Genes for IFN-beta-2 (IL-6), tumor necrosis factor, and IL-1 are expressed at high levels in the organs of normal individuals.

1988 • 119 citations

Expression of myelomonocytic antigens on chronic lymphocytic leukemia B cells correlates with their ability to produce interleukin 1

1987 • 103 citations

In vitro production of interleukin 1 by normal and malignant human B lymphocytes.

1986 • 90 citations

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

1988 • 83 citations

Both interleukin 1 and tumor necrosis factor enhance thymocyte proliferation

1988 • 56 citations

IL-1 inhibits B cell differentiation in long term bone marrow cultures.

1988 • 50 citations

Regulation of B cell maturation and differentiation. I. Suppression of pokeweed mitogen-induced B cell differentiation by tumor necrosis factor (TNF).

1987 • 49 citations

Spontaneous production of interleukin 1 activity by chronic lymphocytic leukemic cells

1987 • 43 citations

Production of Bone-resorbing Activity Corresponding to Interleukin-1α by Adult T-Cell Leukemia Cells in Humans

1988 • 41 citations

Production of growth factors by human myeloma cells.

1987 • 29 citations

Interleukin‐1 producing ability of leukaemia cells and its relationship to morphological diagnosis

1987 • 27 citations

Tumor necrosis factor and interleukin 1 can act as essential growth factors in a murine plasmacytoma line.

1988 • 21 citations

Macromolecular osteolytic factor synthesised by squamous carcinoma cell lines from the head and neck in vitro is interleukin 1

1988 • 11 citations

Clonal rearrangement of the beta-T cell receptor gene in multiple myeloma.

1989 • 11 citations