Bone marrow stromal fibroblasts secrete interleukin-6 and granulocyte- macrophage colony-stimulating factor in the absence of inflammatory stimulation: demonstration by serum-free bioassay, enzyme-linked immunosorbent assay, and reverse transcriptase polymerase chain reaction

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment

1987 • 636 citations

Regulation of Hemopoiesis by Bone Marrow Stromal Cells and Their Products

1990 • 546 citations

Differentiation of T cell lymphokine gene expression: the in vitro acquisition of T cell memory.

1991 • 406 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony- stimulating factor

1988 • 248 citations

Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells.

1987 • 238 citations

Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity.

1985 • 156 citations

Human recombinant granulocyte-macrophage colony stimulating factor and interleukin 3 have overlapping but distinct hematopoietic activities.

1988 • 149 citations

Interleukin‐1 regulation of hematopoietic growth factor production by human stromal fibroblasts

1988 • 136 citations

Regulation of early human hematopoietic (BFU-E and CFU-GEMM) progenitor cells in vitro by interleukin 1-induced fibroblast-conditioned medium

1987 • 70 citations

Characterization of human marrow stromal cells: role in progenitor cell binding and granulopoiesis

1989 • 69 citations

Interleukin-1 induces human bone marrow-derived fibroblasts to produce multilineage hematopoietic growth factors.

1987 • 61 citations

Culture perfusion schedules influence the metabolic activity and granulocyte‐macrophage colony‐stimulating factor production rates of human bone marrow stromal cells

1991 • 59 citations

Nucleotide sequence analysis of human abl and bcr-abl cDNAs.

1989 • 56 citations

Regulation of interleukin 3 gene induction in normal human T cells.

1989 • 52 citations

Comparative analysis of hematopoietic growth factors released by stromal cells from normal donors or transplanted patients [see comments]

1990 • 45 citations

Production of multilineage growth factors by hematopoietic stromal cells: an intercellular regulatory network involving mononuclear phagocytes and interleukin-1.

1987 • 43 citations

Decreased hematopoietic accessory cell function following bone marrow transplantation.

1987 • 14 citations

DEFICIENT T CELL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR PRODUCTION IN ALLOGENEIC BONE MARROW TRANSPLANT RECIPIENTS

1990 • 10 citations

Hematopoiesis of hereditarily asplenic-athymic (lasat) mice.

1979 • 7 citations

The Primary Immunodeficiencies and Serum Complement Defects

1980 • 6 citations

Normal human serum‐stimulating activity on granulocyte‐macrophage colony formation in vitro

1986 • 4 citations