'Role of bone marrow stromal cells in the growth of human multiple myeloma

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Bone acid phosphatase: Tartrate-resistant acid phosphatase as a marker of osteoclast function

1982 • 992 citations

Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6

1989 • 775 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Evidence for the Secretion of an Osteoclast Stimulating Factor in Myeloma

1974 • 681 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release.

1990 • 493 citations

Primary Bioassay of Human Myeloma Stem Cells

1977 • 478 citations

A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro

1986 • 391 citations

Plasma cells in multiple myeloma express a natural killer cell- associated antigen: CD56 (NKH-1; Leu-19)

1990 • 314 citations

Plasma cell myeloma--new biological insights and advances in therapy

1989 • 299 citations

ACID PHOSPHATASE ISOENZYME IN HUMAN LEUKOCYTES IN NORMAL AND PATHOLOGIC CONDITIONS

1970 • 285 citations

Cells and Molecules that Regulate B Lymphopoiesis in Bone Marrow

1989 • 272 citations

B-CELL NEOPLASIA IN MAN

1974 • 271 citations

Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.

1979 • 255 citations

Interleukin-1β is a potent inhibitor of bone formation in vitro

1987 • 251 citations

Response patterns of purified myeloma cells to hematopoietic growth factors

1989 • 231 citations

Immunocytochemical distribution of extracellular matrix receptors in human osteoclasts: A β3 integrin is colocalized with vinculin and talin in the podosomes of osteoclastoma giant cells

1989 • 199 citations

Monoclonal lymphocyte population in human plasma cell myeloma.

1974 • 173 citations

Interleukin 3 and interleukin 6 synergistically promote the proliferation and differentiation of malignant plasma cell precursors in multiple myeloma.

1989 • 163 citations

Evidence for peripheral blood B lymphocyte but not T lymphocyte involvement in multiple myeloma

1987 • 146 citations

Immunoregulation of Murine Myeloma Cell Growth and Differentiation; A Monoclonal Model of B Cell Differentiation¹

1979 • 144 citations

Interleukin-1 accelerates autocrine growth of myeloma cells through interleukin-6 in human myeloma

1989 • 141 citations

Interleukin-1 beta rather than lymphotoxin as the major bone resorbing activity in human multiple myeloma

1989 • 126 citations

Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia

1988 • 114 citations

Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines

1989 • 107 citations

Cytoskeleton organization is aberrantly rearranged in the cells of B chronic lymphocytic leukemia and hairy cell leukemia

1986 • 88 citations

Expression of lymphocyte homing receptor antigen in non-Hodgkin's lymphoma.

1988 • 87 citations

Expression of leucocyte function-associated antigen-1 and 7F7-antigen, an adhesion molecule related to intercellular adhesion molecule-1 (ICAM-1) in non-Hodgkin lymphomas and leukaemias: possible influence on growth pattern and leukaemic behaviour.

1989 • 85 citations

IL-3 induces differentiation of bone marrow precursor cells to osteoclast-like cells.

1989 • 81 citations

Human marrow stromal cells: response to interleukin-6 (IL-6) and control of IL-6 expression

1989 • 55 citations

A quantitative and dynamic study of endothelial cells and megakaryocytes in human long-term bone marrow cultures.

1989 • 13 citations