A GTPase Cycle Coupled to the Cell Cycle

ras GENES

1987 • 3,818 citations

The GTPase superfamily: conserved structure and molecular mechanism

1991 • 3,365 citations

The GTPase superfamily: a conserved switch for diverse cell functions

1990 • 2,330 citations

ANIMAL CELL CYCLES AND THEIR CONTROL

1992 • 1,239 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1991 • 703 citations

Small GTP-Binding Proteins

1992 • 526 citations

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA.

1989 • 367 citations

Regulators and Effectors of ras Proteins

1991 • 303 citations

The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide

1989 • 293 citations

Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line

1990 • 285 citations

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide.

1991 • 281 citations

The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors

1992 • 278 citations

The in vitro replication of DNA containing the SV40 origin.

1990 • 268 citations

The cdc25 M-phase inducer: An unconventional protein phosphatase

1992 • 266 citations

Premature chromosome condensation in a ts DNA-mutant of BHK cells

1978 • 260 citations

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

1991 • 231 citations

Coupling of mitosis to the completion of S phase in Xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2

1992 • 231 citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

1987 • 208 citations

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

1990 • 202 citations

Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis.

1993 • 195 citations

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis.

1991 • 195 citations

RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles

1993 • 192 citations

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

1990 • 152 citations

Nuclear PRP20 protein is required for mRNA export.

1993 • 148 citations

GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.

1993 • 145 citations

Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure.

1992 • 142 citations

RCC1, a Regulator of Mitosis, Is Essential for DNA Replication

1992 • 106 citations

Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants.

1989 • 98 citations

Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene.

1990 • 91 citations

The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1.

1991 • 76 citations

Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm.

1992 • 71 citations

Protein kinases and protooncogenes: biochemical regulators of the eukaryotic cell cycle

1991 • 56 citations

RCC1, a regulator of mitosis, is essential for DNA replication.

1992 • 46 citations

Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase.

1993 • 45 citations

Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus

1991 • 42 citations

Rac and Rho in tune

1992 • 35 citations

Cloning of Xenopus RCC1 cDNA, a Homolog of the Human RCC1 Gene: Complementation of tsBN2 Mutation and Identification of the Product1

1990 • 34 citations

Checkpoint controls that couple mitosis to completion of DNA replication

1992 • 32 citations

Ras-like genes and gene families in the mouse

1991 • 30 citations

Cell type-specific interactions of transcription factors with a housekeeping promoterin vivo

1993 • 23 citations

Counting cells with the new stereology

1992 • 20 citations

Coupling of ras p21 signalling and GTP hydrolysis by GTPase activating proteins

1992 • 19 citations

Summary: Put Out More Flags

1991 • 10 citations

RCC1 Is a Nuclear Protein Required for Coupling Activation of cdc2 Kinase with DNA Synthesis and for Start of the Cell Cycle

1991 • 10 citations

Evolutionary grouping of the RAS-protein family

1991 • 8 citations