Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

1971 • 1,553 citations

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1977 • 1,411 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

THE STRUCTURE OF WATER AND HYDROPHOBIC BONDING IN PROTEINS. III. THE THERMODYNAMIC PROPERTIES OF HYDROPHOBIC BONDS IN PROTEINS^1,2

1962 • 967 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

Mammalian Cell Fusion : Induction of Premature Chromosome Condensation in Interphase Nuclei

1970 • 699 citations

Genetic studies of the lac repressor

1977 • 610 citations

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes

1986 • 534 citations

On the nature of hereditable variation in cultured somatic cells

1976 • 497 citations

Structure of the DNA-Eco RI Endonuclease Recognition Complex at 3 Å Resolution

1986 • 492 citations

Alternative packing arrangements in the hydrophobic core of λrepresser

1989 • 375 citations

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA.

1989 • 367 citations

Expression of functional acetylcholine receptor from cloned cDNAs

1984 • 366 citations

Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein

1988 • 325 citations

Premature chromosome condensation in a ts DNA-mutant of BHK cells

1978 • 260 citations

The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function

1986 • 222 citations

Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.

1987 • 220 citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

1987 • 208 citations

Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte

1987 • 176 citations

Premature chromosome condensation and cell cycle analysis

1977 • 149 citations

The Cell Cycle and the Control of Cellular Reproduction

1976 • 132 citations

Temperature-Sensitive Mutations in Animal Cells

1977 • 94 citations

Molecular cloning of the cDNA of human X chromosomal gene (CCG1) which complements the temperature-sensitive G1 mutants, tsBN462 and ts13, of the BHK cell line.

1988 • 86 citations

Analysis of a method for selecting temperature-sensitive mutants of BHK cells

1978 • 85 citations

Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis

1978 • 74 citations

Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation.

1986 • 68 citations

The synthesis of protein(S) for chromosome condensation may be regulated by a post‐transcriptional mechanism

1981 • 64 citations

Large-scale selection and analysis of temperature-sensitive mutants for cell reproduction from BHK cells

1982 • 45 citations

M-phase promoting factors from eggs of Xenopus laevis.

1985 • 44 citations

Molecular theory of the helix–coil transition in polyamino acids. V. Explanation of the different conformational behavior of valine, isoleucine, and leucine in aqueous solution

1984 • 29 citations

The ‘BN2’ gene, a regulator for the onset of chromosome condensation

1988 • 16 citations

Chromosome condensing factor(s) induced in tsBN2 cells at a nonpermissive temperature: Evidence for transferable material by cell fusion.

1982 • 8 citations

Intragenic localization of amber and temperature-sensitive rpoD mutations affecting RNA polymerase sigma factor of Escherichia coli

1983 • 7 citations