Lineage-independent activation of immune system effector function by myeloid Fc receptors.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Fc Receptors

1991 • 1,220 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Human neutrophil Fc gamma receptor distribution and structure.

1982 • 577 citations

Complete structure and expression in transfected cells of high affinity IgE receptor

1989 • 515 citations

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line.

1984 • 504 citations

Structure and Function of Human and Murine Receptors for IgG

1988 • 468 citations

Cytoplasmic Domain Heterogeneity and Functions of IgG Fc Receptors in B Lymphocytes

1992 • 462 citations

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules

1992 • 438 citations

Activation of T Cells by a Tyrosine Kinase Activation Domain in the Cytoplasmic Tail of CD3 ε

1992 • 430 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

1991 • 391 citations

Cytotoxicity mediated by human Fc receptors for IgG

1989 • 381 citations

Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry.

1986 • 369 citations

Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain

1992 • 333 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

Escherichia coli gpt gene provides dominant selection for vaccinia virus open reading frame expression vectors

1988 • 317 citations

T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

1991 • 307 citations

Organization of the Human and Mouse Low-affinity FcγR Genes: Duplication and Recombination

1990 • 290 citations

Molecular Cloning of the Zeta Chain of the T Cell Antigen Receptor

1988 • 275 citations

Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity

1989 • 259 citations

Calcium and T lymphocyte activation

1989 • 246 citations

Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells

1989 • 231 citations

Multichain immune recognition receptors: similarities in structure and signaling pathways

1992 • 210 citations

Cytotoxic T lymphocyte mediated lysis without release of serine esterase

1987 • 196 citations

A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII

1989 • 189 citations

Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes

1986 • 188 citations

IgE-induced tyrosine phosphorylation of phospholipase C-gamma 1 in rat basophilic leukemia cells.

1991 • 184 citations

Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes

1987 • 174 citations

Activation of Fc gamma RII induces tyrosine phosphorylation of multiple proteins including Fc gamma RII.

1992 • 172 citations

Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.

1990 • 169 citations

Mechanisms for Regulating Expression of Membrane Isoforms of FcγRIII (CD16)

1989 • 162 citations

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

1989 • 159 citations

Regulation of Phagocytosis and [Ca ²⁺ ] _i Flux by Distinct Regions of an Fc Receptor

1991 • 150 citations

Isolation of cDNAs for two distinct human Fc receptors by ligand affinity cloning.

1988 • 148 citations

Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.

1992 • 145 citations

Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains.

1989 • 143 citations

Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization.

1992 • 142 citations

Fc gamma RI and Fc gamma RII on monocytes and granulocytes are cytotoxic trigger molecules for tumor cells.

1987 • 140 citations

Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal.

1991 • 140 citations

A dominant selectable marker for the construction of recombinant poxviruses

1988 • 129 citations

Antibody-cell interactions: Fc receptors

1989 • 126 citations

Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells.

1990 • 92 citations

Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone

1987 • 89 citations

CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells.

1992 • 88 citations

Role of associated gamma-chain in tyrosine kinase activation via murine Fc gamma RIII.

1992 • 83 citations

Stimulation of T cells via the TAP molecule, a member in a family of activating proteins encoded in the Ly-6 locus.

1987 • 70 citations

Relationships between structure and function in the Fc receptor family

1988 • 64 citations

A calcium- and perforin-independent pathway of killing mediated by murine cytolytic lymphocytes.

1987 • 64 citations

The Role of Tyrosine Protein Phosphorylation in Lymphocyte Activation

1991 • 60 citations

Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functions.

1989 • 59 citations

The functional properties of Fcγ RI, II and III on myeloid cells: A comparative study of killing of erythrocytes and tumor cells mediated through the different Fc receptors

1989 • 52 citations

Human monocyte-mediated cytotoxicity: the use of Ig-bearing hybridomas as target cells to detect trigger molecules on the monocyte cell surface.

1987 • 41 citations

Evaluation of the antibody-dependent cytotoxic capabilities of individual human monocytes. Role of Fc gamma RI and Fc gamma RII and the effects of cytokines at the single cell level.

1990 • 37 citations

Structural requirements of the cytoplasmic domains of the human macrophage Fcγ receptor IIa and B cell Fcγ receptor IIb2 for the endocytosis of immune complexes

1991 • 31 citations

T cell activation via cell-surface antigens other than the CD3/T cell receptor complex.

1989 • 4 citations

Relationship between the T-cell receptor-T3 complex and Thy-1.

1989 • 3 citations