Structure and Function of Human and Murine Receptors for IgG

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Human neutrophil Fc gamma receptor distribution and structure.

1982 • 577 citations

The role of membrane receptors for C3b and C3d in phagocytosis.

1977 • 536 citations

Defective Reticuloendothelial System Fc-Receptor Function in Systemic Lupus Erythematosus

1979 • 535 citations

PROPERTIES OF ANTIBODIES CYTOPHILIC FOR MACROPHAGES

1966 • 487 citations

Biological significance of carbohydrate chains on monoclonal antibodies.

1983 • 427 citations

Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes.

1983 • 408 citations

Human monocytes and U937 cells bear two distinct Fc receptors for IgG.

1986 • 337 citations

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells

1983 • 333 citations

The Fc receptor for IgG on human natural killer cells: phenotypic, functional, and comparative studies with monoclonal antibodies.

1984 • 325 citations

Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages.

1975 • 314 citations

Defective Fc-Receptor Functions Associated with the HLA-B8/DRw3 Haplotype

1981 • 305 citations

Lymphocyte Receptors for Immunoglobulin

1976 • 296 citations

IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.

1982 • 285 citations

Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies.

1985 • 249 citations

Human platelet Fc receptor for immunoglobulin G. Identification as a 40,000-molecular-weight membrane protein shared by monocytes.

1985 • 233 citations

Fc receptor-mediated phagocytosis occurs in macrophages at exceedingly low cytosolic Ca2+ levels.

1988 • 193 citations

Fc-dependent inhibition of mouse B cell activation by whole anti-mu antibodies.

1983 • 187 citations

Antigen‐specific cytotoxic T cell and antigen‐specific proliferating T cell clones can be induced to cytolytic activity by monoclonal antibodies against T3

1985 • 175 citations

Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. II. Studies of B73.1 antibody-antigen interaction on the lymphocyte membrane.

1983 • 174 citations

Purificaton of a functional mouse Fc receptor through the use of a monoclonal antibody.

1980 • 173 citations

CD16. Developmentally regulated IgG Fc receptors on cultured human monocytes.

1988 • 170 citations

Blockade of clearance of immune complexes by an anti-F(cγ) receptor monoclonal antibody

1986 • 164 citations

Autoimmune neutropenia of infancy

1986 • 162 citations

The Binding of Human Immunoglobulin G1 Monomer and Small, Covalently Cross-Linked Polymers of Immunoglobulin G1 to Human Peripheral Blood Monocytes and Polymorphonuclear Leukocytes

1982 • 152 citations

Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils.

1986 • 146 citations

Effect of Danazol in Immune Thrombocytopenic Purpura

1987 • 145 citations

Human K/natural killer cells targeted with hetero-cross-linked antibodies specifically lyse tumor cells in vitro and prevent tumor growth in vivo.

1987 • 135 citations

Induction of nonspecific cytotoxicity by monoclonal anti-T3 antibodies.

1985 • 126 citations

IgG Subclass Specificity of Human Monocyte Receptor Sites

1971 • 123 citations

Antibody 3G8, specific for the human neutrophil Fc receptor, reacts with natural killer cells.

1984 • 119 citations

The blockade of Fc receptor-mediated clearance of immune complexes in vivo by a monoclonal antibody (2.4G2) directed against Fc receptors on murine leukocytes.

1984 • 117 citations

A cDNA presumptively coding for the .alpha. subunit of the receptor with high affinity for immunoglobulin E

1987 • 111 citations

Augmentation of macrophage complement receptor function in vitro. I. Characterization of the cellular interactions required for the generation of a T-lymphocyte product that enhances macrophage complement receptor function.

1979 • 106 citations

Receptor for transferrin may be a "target" structure for natural killer cells.

1983 • 103 citations

Role of activated macrophages in antibody-dependent lysis of tumor cells.

1980 • 103 citations

Two distinct classes of IgG Fc receptors on a human monocyte line (U937) defined by differences in binding of murine IgG subclasses at low ionic strength.

1985 • 99 citations

Evidence for sequential signals in the induction of the arachidonic acid cascade in macrophages.

1986 • 80 citations

T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition.

1985 • 68 citations

All classes of murine IgG antibody mediate macrophage phagocytosis and lysis of erythrocytes.

1980 • 68 citations

Analysis of the monocyte Fc receptors and antibody-mediated cellular interactions required for the induction of T cell proliferation by anti-T3 antibodies.

1985 • 68 citations

Augmentation of macrophage complement receptor function in vitro. II. Characterization of the effects of a unique lymphokine upon the phagocytic capabilities of macrophages.

1980 • 66 citations

Comparison of intravenous gamma globulin and a monoclonal anti-Fc receptor antibody as inhibitors of immune clearance in vivo in mice.

1986 • 65 citations

Identification of soluble Fc receptors in mouse serum and the conditioned medium of stimulated B cells.

1984 • 62 citations

Fc receptor-mediated binding and endocytosis by human mononuclear phagocytes: monomeric IgG is not endocytosed by U937 cells and monocytes.

1985 • 53 citations

Circulating cellfree Fc gamma 2b/gamma 1 receptor in normal mouse serum: its detection and specificity.

1984 • 50 citations

Biosynthesis and intracellular transport of the mouse macrophage Fc receptor.

1985 • 48 citations

Induction of mouse IgG2a- and IgG3-dependent cellular cytotoxicity in human monocytic cells (U937) by immune interferon.

1984 • 48 citations

IgG1 and IgG2b share the Fc receptor on mouse macrophages.

1980 • 43 citations

Human monocyte-mediated cytotoxicity: the use of Ig-bearing hybridomas as target cells to detect trigger molecules on the monocyte cell surface.

1987 • 41 citations

Identification of Gamma-Interferon as a Murine Macrophage-Activating Factor for Tumor Cytotoxicity

1984 • 40 citations

Isolation of biosynthetically-labeled Fc-binding proteins from detergent lysates and spent culture fluid of a macrophage-like cell line (P388D1).

1980 • 35 citations

Human large granular lymphocytes express high affinity receptors for murine monoclonal antibodies of the IgG3 subclass.

1987 • 35 citations

Fc receptors on cultured myeloma and hybridoma cells.

1985 • 34 citations

Clq enhancement of IgG-dependent eosinophil-mediated killing of schistosomula in vitro.

1987 • 34 citations

Altered phagocytosis by monocytes from HLA-DR2 and DR3-positive healthy adults is Fc gamma receptor specific.

1986 • 33 citations

The functions of endogenous C1q, a subcomponent of the first component of complement, as a receptor on the membrane of macrophages

1982 • 30 citations

Specific effect of anti-transferrin antibodies on natural killer cells directed against tumor cells. Evidence for the transferrin receptor being one of the target structures recognized by NK cells.

1985 • 29 citations

Immunologic control of the ascites form of murine adenocarcinoma 755. IV. Characterization of the protective antibody in hyperimmune serum.

1981 • 27 citations

Fc receptors of mouse cell lines. I. Distinct proteins mediate the IgG subclass-specific Fc binding activities of macrophages.

1982 • 25 citations

Size and charge heterogeneity of murine IgG-binding factors (IgG-BF).

1986 • 24 citations

Structural requirements of immunoglobulin G for binding to the Fc gamma receptors of the human tumor cell lines U937, HL-60, ML-1, and K562.

1985 • 23 citations

Characterization of a polyvalent antibody directed against the IgG Fc receptor of human mononuclear phagocytes.

1985 • 22 citations

The binding and processing of monoclonal human IgG1 by cells of a human macrophage-like cell line (U937)

1983 • 21 citations

Effects of immunoglobulin structure on Fc receptor binding: a mouse myeloma variant immunoglobulin with a gamma 2b-gamma 2a hybrid heavy chain having a complete gamma 2a Fc region fails to bind to gamma 2a Fc receptors on mouse macrophages.

1982 • 20 citations

The Occurence, Structural and Functional Properties of Immunoglobulin Fc Receptors on Murine Neoplastic Cells

1986 • 18 citations

The valence for ligand of the human mononuclear phagocyte 72 kD high-affinity IgG Fc receptor is one.

1986 • 18 citations

Apparent sensitivity of human K lymphocytes to the spatial orientation and organization of target cell-bound antibodies as measured by the efficiency of antibody-dependent cellular cytotoxicity (ADCC).

1987 • 18 citations

[30] IgG-binding factors

1985 • 18 citations

Site of binding of IgG2b and IgG2a by mouse macrophage Fc receptors by using cyanogen bromide fragments.

1985 • 15 citations

Polymorphism of Fc receptor on murine B cells is Igh-linked.

1985 • 14 citations

Enhancement of human natural killer activity by the monoclonal Leu-11 antibodies

1987 • 13 citations

A sensitive method for testing the effect of immunoglobulin binding factor on Ig secretion by hybridoma B cells

1987 • 12 citations

Monoclonal anti-mouse macrophage antibodies recognize the globular portions of C1q, a subcomponent of the first component of complement.

1984 • 12 citations

Intravenous immunoglobulin therapy for the treatment of idiopathic thrombocytopenic purpura.

1986 • 11 citations

Effects of inhibitors of C1q biosynthesis on macrophage Fc receptor subclass-mediated antibody-dependent cellular cytotoxicity and phagocytosis

1987 • 8 citations