Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats.

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1992 • 1,319 citations

Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry

1994 • 1,138 citations

Inflammation, immunoregulation, and inducible nitric oxide synthase

1993 • 877 citations

Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P.

1994 • 858 citations

Roles of nitric oxide in tumor growth.

1995 • 791 citations

Enzyme-independent formation of nitric oxide in biological tissues

1995 • 783 citations

Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3.

1986 • 602 citations

Mammalian Nitric Oxide Synthases

1992 • 514 citations

Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals.

1996 • 496 citations

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.

1994 • 409 citations

Generation of Free Radicals from Freshly Fractured Silica Dust: Potential Role in Acute Silica-induced Lung Injury

1988 • 319 citations

Immunohistochemical and ultrastructural detection of advanced glycation end products in atherosclerotic lesions of human aorta with a novel specific monoclonal antibody.

1995 • 291 citations

Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia

1994 • 250 citations

Localization of mRNA for c-kit receptor and its ligand in the brain of adult rats: an analysis using in situ hybridization histochemistry

1992 • 226 citations

Enhanced Vascular Permeability in Solid Tumor Is Mediated by Nitric Oxide and Inhibited by Both New Nitric Oxide Scavenger and Nitric Oxide Synthase Inhibitor

1994 • 222 citations

Local opsonization by secreted macrophage complement components. Role of receptors for complement in uptake of zymosan.

1984 • 205 citations

Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth

1996 • 173 citations

Therapeutic Effects of Imidazolineoxyl N-Oxide Against Endotoxin Shock through Its Direct Nitric Oxide-Scavenging Activity

1994 • 142 citations

Tumor-derived monocyte chemoattractant protein-1 induces intratumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors.

1994 • 132 citations

The effect of endogenous nitric oxide on neurogenic plasma exudation in guinea-pig airways

1992 • 130 citations

The role of macrophage inflammatory protein 1 alpha in Schistosoma mansoni egg-induced granulomatous inflammation.

1993 • 126 citations

Characterization and Expression of the Antigen Present on Resident Rat Macrophages Recognized by Monoclonal Antibody ED2

1990 • 114 citations

Intratracheal instillation of silica up-regulates inducible nitric oxide synthase gene expression and increases nitric oxide production in alveolar macrophages and neutrophils.

1994 • 110 citations

Direct evidence for granuloma-inducing activity of interleukin-1. Induction of experimental pulmonary granuloma formation in mice by interleukin-1-coupled beads.

1988 • 91 citations

Effect of neurotropic virus infection on neuronal and inducible nitric oxide synthase activity in rat brain

1995 • 88 citations

Origin and kinetics of pulmonary macrophages during an inflammatory reaction induced by intra-alveolar administration of aerosolized heat-killed BCG.

1983 • 86 citations

Experimental silicosis. II. Long-term effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs.

1983 • 79 citations

Acute experimental silicosis. Lung morphology, histology, and macrophage chemotaxin secretion.

1982 • 75 citations

Pulmonary granuloma formation in the rat is partially dependent on monocyte chemoattractant protein 1.

1993 • 74 citations

Immunohistochemical expression of inducible nitric oxide synthase (iNOS) in reversible endotoxic shock studied by a novel monoclonal antibody against rat iNOS

1995 • 73 citations

Kinetics of macrophage subpopulations and expression of monocyte chemoattractant protein-1 (MCP-1) in bleomycin-induced lung injury of rats studied by a novel monoclonal antibody against rat MCP-1

1994 • 69 citations

Nitric oxide-induced microvascular permeability alterations: a regulatory role for cGMP

1993 • 68 citations

Monocyte chemoattractant protein 1 in a rat model of pulmonary granulomatosis.

1992 • 68 citations

Modulation of macrophage mannosyl-specific receptors by cultivation on immobilized zymosan. Effects on superoxide-anion release and phagocytosis.

1983 • 68 citations

Phagocytosis and induction of nitric oxide synthase in murine macrophages.

1993 • 67 citations

Molecular cloning of a cDNA encoding an inducible calmodulin‐dependent nitric‐oxide synthase from rat liver and its expression in COS 1 cells

1993 • 66 citations

A New Monoclonal Antibody, TRPM-3, Binds Specifically to Certain Rat Macrophage Populations: Immunohistochemical and Immunoelectron Microscopic Analysis

1987 • 60 citations

Group B streptococcus-induced nitric oxide production in murine macrophages is CR3 (CD11b/CD18) dependent

1994 • 56 citations

Modulation of granuloma formation by endogenous nitric oxide

1994 • 51 citations

Enhancement of the expression of a rat neutrophil-specific cell surface antigen by activation with phorbol myristate acetate and concanavalin A.

1986 • 38 citations

In vivo expression of monokine and inducible nitric oxide synthase in experimentally induced pulmonary granulomatous inflammation. Evidence for sequential production of interleukin-1, inducible nitric oxide synthase, and tumor necrosis factor.

1995 • 29 citations

Morphometric analysis of Mycobacterium tuberculosis infection in mice suggests a genetic influence on the generation of the granulomatous inflammatory response

1992 • 20 citations

Stabilization of Inducible Nitric Oxide Synthase by Monoclonal Antibodies

1993 • 11 citations

Altered Release of Eicosanoids by Rat Alveolar Macrophages during Granulomatous Pulmonary Inflammation

1990 • 5 citations