In vivo expression of monokine and inducible nitric oxide synthase in experimentally induced pulmonary granulomatous inflammation. Evidence for sequential production of interleukin-1, inducible nitric oxide synthase, and tumor necrosis factor.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

1989 • 1,269 citations

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

1993 • 1,031 citations

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.

1992 • 616 citations

The granulomatous inflammatory response. A review.

1976 • 549 citations

Progesterone-dependent expression of keratinocyte growth factor mRNA in stromal cells of the primate endometrium: keratinocyte growth factor as a progestomedin.

1994 • 182 citations

Cellular and Molecular Aspects of Granulomatous Inflammation

1989 • 143 citations

Enhanced production of nitric oxide by rat alveolar macrophages after inhalation of a pulmonary irritant is associated with increased expression of nitric oxide synthase.

1993 • 123 citations

Differences in Response Among Inbred Mouse Strains to Infection with Small Doses of Mycobacterium bovis BCG

1981 • 114 citations

Implication of phagosome-lysosome fusion in restriction of Mycobacterium avium growth in bone marrow macrophages from genetically resistant mice

1993 • 112 citations

Granulomatous Inflammations

2015 • 106 citations

Monokine production by hypersensitivity (Schistosoma mansoni egg) and foreign body (Sephadex bead)-type granuloma macrophages. Evidence for sequential production of IL-1 and tumor necrosis factor.

1989 • 103 citations

Localization of estrogen receptor messenger ribonucleic acid in rhesus monkey uterus by nonradioactive in situ hybridization with digoxigenin-labeled oligodeoxynucleotides.

1993 • 99 citations

Tumor necrosis factor plays a role in Schistosoma mansoni egg-induced granulomatous inflammation.

1993 • 97 citations

Regulation of resistance to leprosy by chromosome 1 locus in the mouse

1984 • 96 citations

Direct evidence for granuloma-inducing activity of interleukin-1. Induction of experimental pulmonary granuloma formation in mice by interleukin-1-coupled beads.

1988 • 91 citations

Role of interleukin 1 in experimental pulmonary granuloma in mice.

1985 • 77 citations

Genetic regulation of macrophage priming/activation: the Lsh gene story

1991 • 74 citations

The role monokines in granuloma formation in mice: The ability of interleukin 1 and tumor necrosis factor-α to induce lung granulomas

1989 • 74 citations

Regulation of host resistance toMycobacterium intracellulare in vivo and in vitro by theBcg gene

1989 • 69 citations

Granuloma formation by artificial microparticles in vitro. Macrophages and monokines play a critical role in granuloma formation.

1989 • 61 citations

Localization In Situ of Specific mRNA Using Thymine‐Thymine Dimerized DNA Probes

1990 • 57 citations

Genetics of the immune response to infectious pathogens

1991 • 44 citations

Functional expression of the Bcg gene in macrophages

1989 • 42 citations

Strain variation of bacillus Calmette-Guerin-induced pulmonary granuloma formation is correlated with anergy and the local production of migration inhibition factor and interleukin 1.

1985 • 34 citations

Studies on experimental pulmonary granulomas. I. Detection of lymphokines in granulomatous lesions.

1979 • 21 citations

Regulation of Mycobacterium bovis BCG and foreign body granulomas in mice by the Bcg gene

1990 • 19 citations

Anergy-like immunosuppression in mice bearing pulmonary foreign-body granulomatous inflammation.

1985 • 17 citations