The homeodomain-containing proteins

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

1997 • 2,510 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Hox genes in vertebrate development

1994 • 2,057 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

The CBP co-activator is a histone acetyltransferase

1996 • 1,773 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

1984 • 1,066 citations

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

1994 • 1,046 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

HOMEODOMAIN PROTEINS

1994 • 828 citations

Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and fushi tarazu loci of Drosophila.

1984 • 776 citations

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

1991 • 746 citations

Regulation of activity of the transcription factor GATA-1 by acetylation

1998 • 686 citations

Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals

1997 • 612 citations

Acetylation of general transcription factors by histone acetyltransferases

1997 • 588 citations

Altered Growth and Branching Patterns in Synpolydactyly Caused by Mutations in HOXD13

1996 • 565 citations

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

1995 • 534 citations

Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

1996 • 498 citations

The p300/CBP family: integrating signals with transcription factors and chromatin

1997 • 482 citations

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP96 and class I homeoprotein HOXA9

1996 • 449 citations

Inducible Nuclear Expression of Newly Synthesized IκBα Negatively Regulates DNA-Binding and Transcriptional Activities of NF-κB

1995 • 442 citations

Nuclear Translocation of Extradenticle Requires , which Encodes an Extradenticle-Related Homeodomain Protein

1997 • 440 citations

Guidebook to the homeobox genes

1994 • 399 citations

Homeobox proteins as sequence-specific transcription factors

1988 • 397 citations

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins.

1995 • 396 citations

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1996 • 393 citations

Hox proteins meet more partners

1998 • 377 citations

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling

1998 • 369 citations

Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

1998 • 345 citations

Nuclear uptake control of NF-kappa B by MAD-3, an I kappa B protein present in the nucleus.

1993 • 330 citations

CREB Binding Protein Interacts with Nucleoporin-Specific FG Repeats That Activate Transcription and Mediate NUP98-HOXA9 Oncogenicity

1999 • 322 citations

Structure of a HoxB1–Pbx1 Heterodimer Bound to DNA

1999 • 318 citations

The human HOX gene family

1989 • 317 citations

Signal-specific co-activator domain requirements for Pit-1 activation

1998 • 284 citations

AbdB-Like Hox Proteins Stabilize DNA Binding by the Meis1 Homeodomain Proteins

1997 • 280 citations

Pbx Modulation of Hox Homeodomain Amino-Terminal Arms Establishes Different DNA-Binding Specificities across theHoxLocus

1996 • 274 citations

Guidebook to the Homeobox Genes

1995 • 270 citations

Meis Proteins are Major In Vivo DNA Binding Partners for Wild-Type but Not Chimeric Pbx Proteins

1997 • 255 citations

HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells

1999 • 246 citations

cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates

1992 • 243 citations

Developmental functions of mammalian Hox genes

1997 • 239 citations

PARALOGOUS HOX GENES: Function and Regulation

1996 • 226 citations

Cooperative Interactions between HOX and PBX Proteins Mediated by a Conserved Peptide Motif

1995 • 224 citations

Human DNA sequences homologous to a protein coding region conserved between homeotic genes of Drosophila

1984 • 220 citations

HOXB7 Constitutively Activates Basic Fibroblast Growth Factor in Melanomas

1996 • 211 citations

Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb

1998 • 208 citations

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

1997 • 199 citations

HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

1997 • 195 citations

Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy

1999 • 187 citations

Prep1, a novel functional partner of Pbx proteins

1998 • 177 citations

The Pentapeptide Motif of Hox Proteins Is Required for Cooperative DNA Binding with Pbx1, Physically Contacts Pbx1, and Enhances DNA Binding by Pbx1

1995 • 167 citations

Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis

1998 • 164 citations

Genomic structure of HOXD13 gene: a nine polyalanine duplication causes synpolydactyly in two unrelated families

1996 • 160 citations

Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences

1998 • 142 citations

A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila.

1997 • 119 citations

Characterization of IκBα Nuclear Import Pathway

1999 • 116 citations

Functional and Cooperative Interactions between the Homeodomain PDX1, Pbx, and Prep1 Factors on the Somatostatin Promoter

1999 • 105 citations

Antp-type homeodomains have distinct DNA binding specificities that correlate with their different regulatory functions in embryos.

1992 • 104 citations

Functional dissection of a transcriptionally active, target-specific Hox-Pbx complex

1997 • 104 citations

Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster.

1994 • 77 citations

Pbx Raises the DNA Binding Specificity but Not the Selectivity of Antennapedia Hox Proteins

1997 • 71 citations

A universal target sequence is bound in vitro by diverse homeodomains

1993 • 71 citations

CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein

1999 • 61 citations

A Novel Mechanism for Cyclic Adenosine 3′,5′-Monophosphate Regulation of Gene Expression by CREB-Binding Protein

1999 • 59 citations

I kappa B alpha can localize in the nucleus but shows no direct transactivation potential.

1993 • 41 citations

Definition of the Transcriptional Activation Domains of Three Human HOX Proteins Depends on the DNA-Binding Context

1998 • 40 citations

Homeobox genes in hematopoiesis and leukemogenesis.

1998 • 32 citations

Cloning and expression of a new HOXC6 transcript encoding a repressing protein

1996 • 29 citations

A Novel Mechanism for Cyclic Adenosine 3',5'-Monophosphate Regulation of Gene Expression by CREB-Binding Protein

1999 • 29 citations

IκB-α Enhances Transactivation by the HOXB7 Homeodomain-containing Protein

1999 • 28 citations

DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA.

1994 • 28 citations

Molecular cloning of a mutatedHOXB7 cDNA encoding a truncated transactivating homeodomain-containing protein

1998 • 9 citations

No milk today (my Hox have gone away)

1999 • 9 citations