Cytopathic Feline Leukemia Viruses Cause Apoptosis in Hemolymphatic Cells

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1987 • 923 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

CURRENT VETERINARY THERAPY

1969 • 740 citations

Molecular Characterization of Human T-Cell Leukemia (Lymphotropic) Virus Type III in the Acquired Immune Deficiency Syndrome

1984 • 639 citations

Death and the cell

1986 • 616 citations

Pathogenesis of lentivirus infections

1986 • 558 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Inhibition of Lymphocyte Proliferation by a Synthetic Peptide Homologous to Retroviral Envelope Proteins

1985 • 433 citations

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

1991 • 432 citations

A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus

1991 • 394 citations

Apoptosis: Cell death in tissue regulation

1987 • 393 citations

HIV induces thymus depletion in vivo

1993 • 384 citations

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance.

1990 • 372 citations

The cytopathic effect of hiv is associated with apoptosis

1991 • 358 citations

The Cat: Diseases and Clinical Management

1995 • 354 citations

Selective Depletion in HIV Infection of T Cells that Bear Specific T Cell Receptor V _β Sequences

1991 • 322 citations

Programmed Cell Death in AIDS-Related HIV and SIV Infections

1993 • 316 citations

Detection of Human T-Cell Lymphoma/Leukemia Virus Type I DNA and Antigen in Spinal Fluid and Blood of Patients with Chronic Progressive Myelopathy

1988 • 279 citations

Horizontal Transmission of Feline Leukaemia Virus

1973 • 278 citations

Involvement of a Leukocyte Adhesion Receptor (LFA-1) in HIV-Induced Syncytium Formation

1989 • 264 citations

Molecular Cloning of a Feline Leukemia Virus That Induces Fatal Immunodeficiency Disease in Cats

1988 • 258 citations

Cellular signalling in programmed cell death (apoptosis)

1990 • 255 citations

Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.

1994 • 250 citations

Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses

1992 • 242 citations

Radiation-induced Interphase Death of Rat Thymocytes is Internally Programmed (Apoptosis)

1988 • 239 citations

Infectious Mutants of HTLV-III with Changes in the 3′ Region and Markedly Reduced Cytopathic Effects

1986 • 236 citations

Subgroup classification of feline leukemia and sarcoma viruses by viral interference and neutralization tests

1973 • 231 citations

Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection

1992 • 208 citations

Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells

1987 • 201 citations

A Spontaneous Lower Motor Neuron Disease Apparently Caused by Indigenous Type-C RNA Virus in Wild Mice2

1973 • 200 citations

Nucleotide sequences of a feline leukemia virus subgroup A envelope gene and long terminal repeat and evidence for the recombinational origin of subgroup B viruses

1986 • 199 citations

A Virus-Encoded "Superantigen" in a Retrovirus-Induced Immunodeficiency Syndrome of Mice

1991 • 198 citations

Transduction and rearrangement of the myc gene by feline leukaemia virus in naturally occurring T-cell leukaemias

1984 • 196 citations

Strong sequence conservation among horizontally transmissible, minimally pathogenic feline leukemia viruses

1988 • 174 citations

Disease-specific and tissue-specific production of unintegrated feline leukaemia virus variant DNA in feline AIDS

1986 • 171 citations

The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion.

1991 • 168 citations

Horizontal Transmission of Leukemia Virus and Leukemia in the Cat

1973 • 164 citations

Unifying concepts of leukemia

1973 • 161 citations

Correlation between cell killing and massive second-round superinfection by members of some subgroups of avian leukosis virus

1980 • 158 citations

Leukæmia in the Cat: Transmission Experiments with Leukæmia (Lymphosarcoma)

1964 • 158 citations

Association of feline leukemia virus with lymphosarcoma and other disorders in the cat.

1975 • 157 citations

Evolution of Type C Viral Genes: Origin of Feline Leukemia Virus

1975 • 146 citations

The Cat: Diseases and Clinical Management

1994 • 142 citations

Pathogenesis of Experimental Feline Leukemia Virus Infection2

1979 • 142 citations

Viral transduction of c-myc gene in naturally occurring feline leukaemias

1984 • 141 citations

Inhibition of radiation-induced apoptosis in vitro by tumor promoters

1988 • 138 citations

Abrogation of lymphocyte blastogenesis by a feline leukaemia virus protein

1978 • 135 citations

In vitro suppression of normal human bone marrow progenitor cells by human immunodeficiency virus

1991 • 133 citations

Selective thymocyte depletion in neonatal HIV-1 thymic infection

1993 • 129 citations

The frequency of occurrence of feline leukaemia virus subgroups in cats

1978 • 127 citations

Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion.

1990 • 124 citations

Thymic Abnormalities in Fetuses Aborted From Human Immunodeficiency Virus Type 1 Seropositive Women

1992 • 124 citations

Nucleotide Sequence of the Envelope Gene of Gardner-Arnstein Feline Leukemia Virus B Reveals Unique Sequence Homologies with a Murine Mink Cell Focus-Forming Virus

1983 • 118 citations

Alterations in Cell Membrane Permeability by the Lentivirus Lytic Peptide (LLP-1) of HIV-1 Transmembrane Protein

1993 • 117 citations

Differential binding of erythroid and myeloid progenitors to fibroblasts and fibronectin

1987 • 109 citations

Isolation of a feline leukaemia provirus containing the oncogene myc from a feline lymphosarcoma

1984 • 109 citations

Advances in comparative leukemia research

1983 • 109 citations

A Structural Correlation Between Lentivirus Transmembrane Proteins and Natural Cytolytic Peptides

1991 • 107 citations

Molecular analysis and pathogenesis of the feline aplastic anemia retrovirus, feline leukemia virus C-Sarma

1986 • 105 citations

Defective endogenous proviruses are expressed in feline lymphoid cells: evidence for a role in natural resistance to subgroup B feline leukemia viruses

1994 • 101 citations

The mechanism of retrovirus suppression of human T cell proliferation in vitro.

1983 • 101 citations

Excretion of feline leukaemia virus by naturally infected pet cats

1977 • 101 citations

Human immunodeficiency virus (HIV-1) cytotoxicity: Perturbation of the cell membrane and depression of phospholipid synthesis

1988 • 98 citations

Simian immunodeficiency virus?induced meningoencephalitis: Natural history and retrospective study

1988 • 97 citations

Selective effect of feline leukaemia virus on early erythroid precursors

1982 • 96 citations

Viral genetic determinants of T-cell killing and immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS

1991 • 94 citations

Anemia Associated With Feline Leukemia Virus Infection in Cats 2

1975 • 94 citations

Retroviral Spongiform Polioencephalomyelopathy

1985 • 92 citations

Experimental transmission and pathogenesis of immunodeficiency syndrome in cats

1987 • 85 citations

Determinants of Susceptibility and Resistance to Feline Leukemia Virus Infection. I. Role of Macrophages23

1981 • 83 citations

Erythroid Hypoplasia in Cats Inoculated With Feline Leukemia Virus 2

1974 • 83 citations

Differential growth and transmission in cats of feline leukaemia viruses of subgroups A and B

1978 • 78 citations

Feline Leukemia-Virus Infection of Kittens: Mortality Associated With Atrophy of the Thymus and Lymphoid Depletion<xref ref-type="fn" rid="FN1">2</xref>

1971 • 77 citations

Apoptosis induced by tumor necrosis factor in cells chronically infected with feline immunodeficiency virus

1993 • 74 citations

Pathogenic and host range determinants of the feline aplastic anemia retrovirus.

1988 • 73 citations

Identification of a Calmodulin-Binding and Inhibitory Peptide Domain in the HIV-1 Transmembrane Glycoprotein

1993 • 71 citations

Characterization of human marrow stromal cells: role in progenitor cell binding and granulopoiesis

1989 • 69 citations

Partial dissociation of subgroup C phenotype and in vivo behaviour in feline leukaemia viruses with chimeric envelope genes

1992 • 64 citations

Molecular cloning and characterization of endogenous feline leukemia virus sequences from a cat genomic library

1983 • 64 citations

Structural diversity and nuclear protein binding sites in the long terminal repeats of feline leukemia virus

1990 • 62 citations

Lymphocyte Mitogen Reactivity and Enumeration of Circulating B- and T-Cells During Feline Leukemia Virus Infection in the Cat23

1976 • 61 citations

Simian immunodeficiency virus inhibits bone marrow hematopoietic progenitor cell growth

1990 • 61 citations

Characterization of Feline T- and B-Lymphocytes and Identification of an Experimentally Induced T-Cell Neoplasm in the Cat23

1976 • 61 citations

Perturbation of host-cell membrane is a primary mechanism of HIV cytopathology

1991 • 61 citations

Lymphocyte subset alterations and viral determinants of immunodeficiency disease induction by the feline leukemia virus FeLV-FAIDS

1990 • 59 citations

Self superantigens?

1990 • 59 citations

Retrovirus-mediated immunosuppression. I. FeLV-UV and specific FeLV proteins alter T lymphocyte behavior by inducing hyporesponsiveness to lymphokines.

1985 • 59 citations

Aberrant expression of cytokine genes in peritoneal macrophages from mice infected with LP-BM5 MuLV, a murine model of AIDS.

1991 • 58 citations

Unique lentivirus-host interactions: SIVsmmPBj14 infection of macaques

1994 • 55 citations

Two subpopulations of human triple-negative thymic cells are susceptible to infection by human immunodeficiency virus type 1 in vitro

1994 • 55 citations

Posttranslational modifications distinguish the envelope glycoprotein of the immunodeficiency disease-inducing feline leukemia virus retrovirus

1989 • 53 citations

Programmed cell death (apoptosis) as a mechanism of cell death in peripheral blood mononuclear cells from cats infected with feline immunodeficiency virus (FIV)

1993 • 53 citations

Retroviral transduction of T-cell antigen receptor β-chain and myc genes

1987 • 52 citations

Lymphocytotoxic strains of feline leukemia virus induce apoptosis in feline T4-thymic lymphoma cells.

1992 • 48 citations

flvi-1, a common integration domain of feline leukemia virus in naturally occurring lymphomas of a particular type

1990 • 47 citations

Molecular analysis of several classes of endogenous feline leukemia virus elements

1985 • 47 citations

Inhibition of protein kinase C and anti-CD3-induced Ca2+ influx in Jurkat T cells by a synthetic peptide with sequence identity to HIV-1 gp41.

1990 • 46 citations

Thymic microenvironment induces HIV expression:physiologic secretion of IL-6 by thymic epithelial cells up-regulates virus expression in chronically infected cells

1992 • 45 citations

Interaction between feline leukaemia virus subgroups in the pathogenesis of erythroid hypoplasia

1984 • 44 citations

Molecular cloning and characterization of a defective recombinant feline leukaemia virus associated with myeloid leukaemia

1990 • 44 citations

Recombination between feline leukemia virus subgroup B or C and endogenous env elements alters the in vitro biological activities of the viruses

1991 • 43 citations

Feline Oncornavirus-Associated Cell Membrane Antigen. IV. Antibody Titers in Cats With Naturally Occurring Leukemia, Lymphoma, and Other Diseases&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;

1975 • 41 citations

Altered structure and expression of c-myc in Feline T-cell tumours

1987 • 41 citations

Feline glucose-6-phosphate dehydrogenase cellular mosaicism. Application to the study of retrovirus-induced pure red cell aplasia.

1985 • 41 citations

Feline leukemia virus subgroup C phenotype evolves through distinct alterations near the N terminus of the envelope surface glycoprotein.

1992 • 40 citations

Retrovirus-induced feline pure red blood cell aplasia: pathogenesis and response to suramin

1991 • 40 citations

Early lesions in cats inoculated with feline leukemia virus.

1973 • 39 citations

Haemopoietic colony formation (BFU-E, GM-CFC) during the development of pure red cell hypoplasia induced in the cat by feline leukaemia virus

1983 • 39 citations

Retrovirus-induced feline pure red cell aplasia. Hematopoietic progenitors are infected with feline leukemia virus and erythroid burst-forming cells are uniquely sensitive to heterologous complement.

1987 • 39 citations

Nucleotide sequences of the envelope genes of two isolates of feline leukemia virus subgroup B

1984 • 38 citations

Retrovirus‐induced feline pure red cell aplasia: The kinetics of erythroid marrow failure

1987 • 35 citations

Alterations of thymus cortical epithelium and interdigitating dendritic cells but no increase of thymocyte cell death in the early course of simian immunodeficiency virus infection.

1993 • 35 citations

Inhibition of human immunodeficiency virus (HIV-1) infection by diphenylhydantoin (dilantin) implicates role of cellular calcium in virus life cycle

1989 • 34 citations

Feline Leukemia Virus-associated Enteritis—A Condition with Features of Feline Panleukopenia

1987 • 34 citations

Thymic microenvironment induces HIV expression. Physiologic secretion of IL-6 by thymic epithelial cells up-regulates virus expression in chronically infected cells.

1991 • 34 citations

Erythrocyte Macrocytosis in Feline Leukemia Virus Associated Anemia

1983 • 33 citations

Induction of apoptosis in a T lymphoblastoid cell line infected with feline immunodeficiency virus

1994 • 31 citations

Hematopoietic target cells of anemogenic subgroup C versus nonanemogenic subgroup A feline leukemia virus

1992 • 31 citations

Reactivation of human immunodeficiency virus type 2 in macaques after simian immunodeficiency virus SIVmac superinfection

1995 • 31 citations

Intranasal Transmission of Feline Leukemia&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1972 • 30 citations

Characterization and significance of delayed processing of the feline leukemia virus FeLV-FAIDS envelope glycoprotein

1990 • 30 citations

Induction of aplastic anemia by intra-bone marrow inoculation of a molecularly cloned feline retrovirus

1989 • 28 citations

Inhibition of erythroid colony-forming cells by a Mr 15,000 protein of feline leukemia virus.

1984 • 26 citations

Variation in T‐lymphocyte activation and susceptibility to SIV_PBj‐14‐induced acute death in macaques

1991 • 26 citations

Structure and pathogenicity of individual variants within an immunodeficiency disease-inducing isolate of FeLV

1992 • 26 citations

Feline leukemia virus-induced erythroid aplasia: in vitro hemopoietic culture studies.

1981 • 26 citations

Ultrastructure of the thymus in chicks inoculated with chicken anaemia agent (msb1‐tk5803 strain)

1989 • 25 citations

In vitro replication and cytopathogenicity of the feline immunodeficiency virus for feline t4 thymic lymphoma 3201 cells

1990 • 24 citations

Studies in feline long-term marrow culture: hematopoiesis on normal and feline leukemia virus infected stromal cells

1992 • 23 citations

Detection of Feline Paraffin Embedding Leukemia Virus in Tissues of Cats by a Paraffin Embedding Immunofluorescence Procedure2

1978 • 22 citations

Disease progression and viral genome variants in experimental feline leukemia virus-induced immunodeficiency syndrome.

1991 • 22 citations

Elevation of feline interleukin 6-like activity in feline immunodeficiency virus infection

1992 • 21 citations

Interference with superinfection and with cell killing and determination of host range and growth kinetics mediated by feline leukemia virus surface glycoproteins

1993 • 20 citations

Leukemia and Lymphoma: Infrequent Manifestations of Common Viral Infections? A Review

1978 • 19 citations

Colony forming T lymphocyte deficit in the development of feline retrovirus induced immunodeficiency syndrome

1989 • 19 citations

Determinants of Susceptibility and Resistance to Feline Leukemia Virus Infection. II. Susceptibility of Feline Lymphocytes to Productive Feline Leukemia Virus Infection&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1981 • 18 citations

Studies in feline long-term marrow culture: hematopoiesis on normal and feline leukemia virus infected stromal cells

1992 • 18 citations

FeLV-FAIDS-induced immunodeficiency syndrome in cats

1989 • 18 citations

Multilineage, non‐species specific hematopoietic growth factor(s) elaborated by a feline fibroblast cell line: Enhancement by virus infection

1986 • 18 citations

Serum Erythropoietin Changes in Cats with Feline Leukemia Virus-induced Erythroid Aplasia

1983 • 14 citations

Feline leukemia virus infections: The significance of chronic viremia

1979 • 14 citations

Infectious feline leukaemia virus is erythrosuppressive in vitro

1986 • 13 citations

Characterization of fibroblast colony-forming units in bone marrow from healthy cats.

1988 • 13 citations

In vivo infection of marrow stromal fibroblasts by feline leukemia virus.

1992 • 13 citations

Cytotoxicity in feline leukemia virus subgroup-c infected fibroblasts is mediated by adherent bone marrow mononuclear cells

1992 • 12 citations

Macrophage tropism of feline leukemia virus (FeLV) of subgroup-C and increased production of tumor necrosis factor-alpha by FeLV-infected macrophages

1993 • 12 citations

Experimental Horizontal Transmission of Feline Leukemia Viruses of Subgroups A, B, and C 2

1978 • 12 citations

In vitro erythrocytopathic activity of an aplastic anemia-inducing feline retrovirus.

1989 • 12 citations

Suppression of feline bone marrow fibroblast colony-forming units by feline leukemia virus.

1988 • 11 citations

Effects of tumor necrosis factor-alpha on normal feline hematopoietic progenitor cells.

1992 • 10 citations

Quantitative studies of erythropoiesis in the clinically normal, phlebotomized, and feline leukemia virus-infected cat.

1986 • 10 citations

Animal Models for Perinatal Transmission of Pathogenic Viruses^a

1993 • 9 citations

Reversal of feline retroviral suppression by indomethacin

1985 • 9 citations

FeLV-induced immunosuppression through alterations in signal transduction: Down regulation of protein kinase C

1989 • 8 citations

Brief Communication : Effect of Feline Leukemia Virus on Transferred Hamster Fetuses 2

1974 • 8 citations

Demonstration of retroviral proteins associated with erythroid progenitors of cats with feline leukemia virus-induced erythroid aplasia

1987 • 8 citations

Comparison of feline leukemia virus-infected and normal cat T-cell lines in interleukin 2-conditioned medium.

1984 • 6 citations

EFFECT OF FREE FATTY ACIDS ON THE CYTOLYTIC ACTIVITY OF TUMOUR NECROSIS FACTOR/MONOCYTE‐DERIVED CYTOTOXIC FACTOR

1987 • 4 citations

Chronic Feline Leukemia Virus Infection Alters Arachidonic Acid Proportions In Vivo and In Vitro

1993 • 2 citations

Variable suppression of feline bone marrow fibroblast colony-forming units by two isolates of feline leukemia virus.

1991 • 2 citations

Synergistic effects of tumour necrosis factor-? and interferon-? on feline haemopoietic progenitors

1992 • 1 citations

Effects of increasing cyclic amp or calcium on feline erythroid progenitors in vitro: Normal cells are stimulated while cells from retrovirus‐infected cats are suppressed

1988 • 1 citations

Variable suppression of feline bone marrow fibroblast colony-forming units by two isolates of feline leukemia virus

1991 • 1 citations