HIV induces thymus depletion in vivo

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1991 • 4,682 citations

The SCID-hu Mouse: Murine Model for the Analysis of Human Hematolymphoid Differentiation and Function

1988 • 1,394 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

Dual Infection of the Central Nervous System by AIDS Viruses with Distinct Cellular Tropisms

1987 • 831 citations

Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.

1992 • 689 citations

Do all programmed cell deaths occur via apoptosis?

1993 • 545 citations

Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry

1992 • 542 citations

Comparative evaluation of several DNA binding dyes in the detection of apoptosis‐associated chromatin degradation by flow cytometry

1992 • 375 citations

Infection of the SCID-hu Mouse by HIV-1

1988 • 368 citations

Long-term human hematopoiesis in the SCID-hu mouse.

1990 • 353 citations

Changes in the Human Thymus During Aging

1986 • 341 citations

Positive selection of the T cell repertoire: Where and when does it occur?

1989 • 242 citations

T-Cell Differentiation is Influenced by Thymic Microenvironments

1991 • 239 citations

In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes.

1991 • 199 citations

The SCID-hu Mouse: A Small Animal Model for HIV Infection and Pathogenesis

1991 • 134 citations

Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.

1993 • 130 citations

Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent.

1991 • 130 citations

Thymic Abnormalities in Fetuses Aborted From Human Immunodeficiency Virus Type 1 Seropositive Women

1992 • 124 citations

HIV-1: The infective process in vivo

1991 • 113 citations

The thymus in acquired immune deficiency syndrome. Comparison with other types of immunodeficiency diseases, and presence of components of human immunodeficiency virus type 1.

1989 • 86 citations

Thymus biopsy in children with acquired immunodeficiency syndrome.

1986 • 84 citations

Deletion of antigen-specific immature thymocytes by dendritic cells requires LFA-1/ICAM interactions.

1992 • 81 citations

Thymus in simian immunodeficiency virus-infected rhesus monkeys.

1991 • 67 citations

Cytotoxic T lymphocytes induce different types of DNA damage in target cells of different origins.

1991 • 55 citations

Clonal analysis of the peripheral T cell compartment of the SCID-hu mouse.

1991 • 54 citations

In vivo induction of apoptosis in immature thymocytes by staphylococcal enterotoxin B.

1992 • 48 citations

Infection of cultured human thymic epithelial cells by human immunodeficiency virus

1989 • 29 citations