EFFECT OF FREE FATTY ACIDS ON THE CYTOLYTIC ACTIVITY OF TUMOUR NECROSIS FACTOR/MONOCYTE‐DERIVED CYTOTOXIC FACTOR

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1985 • 1,125 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells.

1985 • 833 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia

1985 • 525 citations

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1985 • 464 citations

Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

1980 • 398 citations

Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells. I. Effectors belong to the monocyte-macrophage lineage.

1984 • 271 citations

Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor

1985 • 240 citations

The Dynamics Of Membrane Structur

1980 • 134 citations

Tumour-necrosis factor from the rabbit. II. Production by monocytes

1978 • 116 citations

Lipopolysaccharide-treated RAW 264.7 cells produce a mediator that inhibits lipoprotein lipase in 3T3-L1 cells.

1985 • 66 citations

Human Monocyte-mediated Cytotoxicity to K-562 Cells: Activation by Lymphokines

1979 • 63 citations

Inhibition of nonspecific tumoricidal activity by activated macrophages with antiserum against a soluble cytotoxic factor

1981 • 62 citations

Physicochemical characterization of cytostatic factors released from human monocytes

1982 • 61 citations

Specificity of In Vivo Tumor Rejection Assessed by Mixing Immune Spleen Cells with Target and Unrelated Tumor Cells

1973 • 56 citations

A Rapid Assay for Cytotoxicity of Unstimulated Human Monocytes23

1984 • 55 citations

Soluble Cytostatic Factor(s) Released from Human Monocytes.

1982 • 38 citations

Production and characterization of cytostatic protein factors released from human monocytes during exposure to lipopolysaccharide and muramyl dipeptide

1985 • 31 citations

Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor involved in monocyte-mediated cytotoxicity.

1987 • 23 citations

Purification of Cytostatic Protein Factors Released from Human Monocytes

1984 • 21 citations

Effect of lymphokines on the production of cytostatic protein factors from human monocytes

1984 • 19 citations

Role of monocyte cytotoxic factor in cytolysis of actinomycin D-treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells.

1986 • 19 citations

The role of monocyte cytotoxic factor in monocyte-mediated lysis of tumour cells.

1986 • 13 citations

Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells

1986 • 11 citations

Rapid Killing of Actinomycin D-Treated Tumor Cells by Mononuclear Phagocytes: Characterization of Effector Cells in Mice

1986 • 10 citations

The role of monocyte cytotoxic factor (CF) in cytostasis mediated by IFN-gamma-activated monocytes.

1985 • 9 citations

Human Monocyte-Released Cytotoxic Factor: Effect on Various Cellular Functions, and Dependency of Cytolysis on Various Metabolic Processes

1986 • 6 citations

Monocyte-mediated drug-dependent cellular cytotoxicity: effects on different WEHI 164 Target cell lines

1986 • 4 citations

WEHI 164 sarcoma cells rendered resistant to monocyte-released cytotoxin are also resistant to monocyte-induced cytolysis

1986 • 4 citations