The Importance of TGF-β in Murine Visceral Leishmaniasis

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg

1993 • 1,107 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Recombinant interleukin 12 cures mice infected with Leishmania major.

1993 • 776 citations

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response.

1993 • 738 citations

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 • 629 citations

Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice.

1993 • 612 citations

Interleukin 10 production correlates with pathology in human Leishmania donovani infections.

1993 • 445 citations

Transforming Growth Factor-β in Leishmanial Infection: a Parasite Escape Mechanism

1992 • 439 citations

The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β

1992 • 437 citations

Modulation of Macrophage Function by Transforming Growth Factor ?, Interleukin-4, and Interleukin-10

1993 • 393 citations

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma.

1993 • 345 citations

Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta).

1991 • 309 citations

Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis.

1996 • 263 citations

Regulation of NK cell functions by TGF-beta 1.

1995 • 241 citations

Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis.

1991 • 231 citations

T-cell and cytokine responses in leishmaniasis

1993 • 221 citations

Transforming growth factor beta as a virulence mechanism for Leishmania braziliensis.

1993 • 217 citations

Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production.

1996 • 212 citations

Immunologic Markers of Clinical Evolution in Children Recently Infected with Leishmania donovani chagasi

1992 • 179 citations

Endogenous IL-12 is required for control of Th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice.

1995 • 162 citations

IL-6 produced by macrophages infected with Mycobacterium species suppresses T cell responses.

1997 • 158 citations

TGF-β Promotes Immune Deviation by Altering Accessory Signals of Antigen-Presenting Cells

1998 • 155 citations

Expression of the natural resistance gene Lsh in resident liver macrophages

1984 • 146 citations

Factors Involved in the Differentiation of TGF-β-Producing Cells from Naive CD4+ T Cells: IL-4 and IFN-γ Have Opposing Effects, While TGF-β Positively Regulates Its Own Production

1998 • 145 citations

Mechanism of lethal effect of human serum upon Leishmania donovani.

1980 • 142 citations

Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection

1995 • 138 citations

Leishmania donovani chagasi: new clinical variant of cutaneous leishmaniasis in Honduras

1991 • 129 citations

Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria.

1997 • 127 citations

Acquired resistance and granuloma formation in experimental visceral leishmaniasis. Differential T cell and lymphokine roles in initial versus established immunity.

1992 • 118 citations

Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse.

1996 • 115 citations

Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi.

1996 • 115 citations

Interleukin-10 Modulates the Severity of Hypersensitivity Pneumonitis in Mice

1998 • 94 citations

TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.

1995 • 93 citations

Leishmania donovani infection in scid mice: lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural killer cell-derived gamma interferon production in vitro

1992 • 79 citations

Assays for transforming growth factor β

1991 • 77 citations

Transforming Growth Factor β and Immunosuppression in Experimental Visceral Leishmaniasis

1998 • 73 citations

Behavior of Visceral Leishmania donovani in an Experimentally Induced T Helper Cell 2 (Th2)-Associated Response Model

1997 • 71 citations

Exogenous and Endogenous Transforming Growth Factors- β Influence Elastin Gene Expression in Cultured Lung Fibroblasts

1997 • 69 citations

Functional interaction between TGF-beta and IL-12 in human primary allogeneic cytotoxicity and proliferative response.

1997 • 65 citations

GENETIC ANALYSIS OF LEISHMANIA MEXICANA INFECTION IN MICE: SINGLE GENE (Scl‐2) CONTROLLED PREDISPOSITION TO CUTANEOUS LESION DEVELOPMENT

1990 • 59 citations

Vaccination routes that fail to elicit protective immunity against Schistosoma mansoni induce the production of TGF-beta, which down-regulates macrophage antiparasitic activity.

1995 • 40 citations

IL-4 antagonizes induction of Fc gamma RIII (CD16) expression by transforming growth factor-beta on human monocytes.

1991 • 36 citations

Transforming growth factor beta is protective in host resistance against Listeria monocytogenes infection in mice

1996 • 30 citations

Cellular Resistance to Protozoal Infection

1986 • 25 citations

Genetic control of systemic Leishmania major infections: dissociation of intrahepatic amastigote replication from control by the Lsh gene

1985 • 20 citations

Gamma interferon suppresses acute and chronic Trypanosoma cruzi infection in cyclosporin-treated mice

1991 • 17 citations

Nature of resistance to Leishmaniasis in experimental rodents

1982 • 16 citations

Leishmaniasis

1990 • 4 citations

Trends in Autometallographic Silver Amplification of Colloidal Gold Particles

2024 • 1 citations