Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta).

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Deactivation of macrophages by transforming growth factor-β

1988 • 876 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma.

1990 • 507 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

Activation of macrophages in vivo and in vitro. Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi.

1979 • 334 citations

Modulation of cytokine production by transforming growth factor-beta.

1989 • 331 citations

Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells.

1988 • 298 citations

In vivo administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections.

1988 • 256 citations

Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.

1987 • 215 citations

Transforming growth factor-beta inhibits the in vitro generation of lymphokine-activated killer cells and cytotoxic T cells

1988 • 155 citations

Differential susceptibility of activated macrophage cytotoxic effector reactions to the suppressive effects of transforming growth factor-beta 1.

1991 • 147 citations

Activity of recombinant tumor necrosis factor on Toxoplasma gondii and Trypanosoma cruzi.

1986 • 143 citations

Enhancing effects of gamma interferon on phagocytic cell association with and killing of Trypanosoma cruzi

1985 • 87 citations

Synergistic protection by specific antibodies and interferon against infection by Trypanosoma cruzi in vitro

1984 • 87 citations

Restoration of in vitro immune responses of spleen cells from mice infected with Trypanosoma cruzi by supernatants containing interleukin 2.

1984 • 74 citations

γ‐Interferon‐Induced Activation of Latent Transforming Growth Factor‐β by Human Monocytes

1990 • 73 citations

Heterologous antibody responses in mice with chronic T. cruzi infection: depressed T helper function restored with supernatants containing interleukin 2.

1984 • 55 citations

Bone-derived and recombinant transforming growth factor β′S are potent inhibitors of tumor cell growth

1987 • 50 citations

Immune deficiency in chronic Trypanosoma cruzi infection. Recombinant IL-1 restores Th function for antibody production.

1989 • 46 citations

Enhancement of tumor growth correlates with suppression of the tumor-specific cytolytic T lymphocyte response in mice chronically infected by Trypanosoma cruzi.

1985 • 37 citations

Spleen cell-mediated suppression of IgG production to a non-parasite antigen during chronic Trypanosoma cruzi infection in mice.

1983 • 35 citations

Suppressed antibody responses to sheep erythrocytes in mice with chronic Trypanosoma cruzi infections are restored with interleukin 2.

1984 • 34 citations

Recombinant granulocyte-macrophage colony-stimulating factor restores deficient immune responses in mice with chronic Trypanosoma cruzi infections.

1990 • 31 citations