Exogenous and Endogenous Transforming Growth Factors- β Influence Elastin Gene Expression in Cultured Lung Fibroblasts

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development.

1991 • 677 citations

Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation.

1989 • 502 citations

Embryonic gene expression patterns of TGF β1, β2 and β3 suggest different developmental functions in vivo

1991 • 499 citations

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.

1993 • 470 citations

Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

1989 • 453 citations

TGF-beta 1, but not TGF-beta 2 or TGF-beta 3, is differentially present in epithelial cells of advanced pulmonary fibrosis: an immunohistochemical study.

1996 • 326 citations

cDNA cloning by PCR of rat transforming growth factor β-1

1990 • 274 citations

Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

1984 • 272 citations

Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides.

1991 • 243 citations

Developmental Regulation of Elastin Production.

1995 • 167 citations

Complementary DNA Cloning of the Murine Transforming Growth Factor-β3 (TGFβ3) Precursor and the Comparative Expression of TGFβ3 and TGFβ1 Messenger RNA in Murine Embryos and Adult Tissues

1989 • 157 citations

Insulin-like growth factor-I regulates transcription of the elastin gene

1993 • 136 citations

Transforming growth factor-beta up-regulates elastin gene expression in human skin fibroblasts. Evidence for post-transcriptional modulation.

1992 • 136 citations

Expression of Transforming Growth Factor-β₁, -β₂, and -β₃ mRNA and Protein in the Murine Lung

1991 • 127 citations

Structural and functional characterization of the transforming growth factor beta 3 promoter. A cAMP-responsive element regulates basal and induced transcription.

1990 • 124 citations

The metabolism of poly(A)+ and poly(A)− hnRNA in cultured drosophila cells studied with a rapid uridine pulse-chase

1977 • 116 citations

Tumor necrosis factor-alpha down-regulates human elastin gene expression. Evidence for the role of AP-1 in the suppression of promoter activity.

1992 • 106 citations

Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form.

1992 • 92 citations

Transcriptional Regulation of the Elastin Gene by Insulin-like Growth Factor-I Involves Disruption of Sp1 Binding

1995 • 86 citations

Human recombinant interleukin-1 beta up-regulates elastin gene expression in dermal fibroblasts. Evidence for transcriptional regulation in vitro and in vivo.

1993 • 79 citations

Glucocorticoids stimulate elastin production in differentiated bovine ligament fibroblasts but do not induce elastin synthesis in undifferentiated cells.

1984 • 72 citations

Cloning and Expression of Glucocorticoid-induced Genes in Fetal Rat Lung Fibroblasts

1995 • 71 citations

1,25-Dihydroxyvitamin D3 represses tropoelastin expression by a posttranscriptional mechanism.

1992 • 61 citations

Transforming Growth Factor-β Increases Elastin Production by Neonatal Rat Lung Fibroblasts

1990 • 59 citations

Recombinant interleukin-1 beta inhibits elastin formation by a neonatal rat lung fibroblast subtype.

1991 • 54 citations

Basic fibroblast growth factor decreases elastin production by neonatal rat lung fibroblasts.

1994 • 52 citations

Phorbol ester-mediated downregulation of tropoelastin expression is controlled by a posttranscriptional mechanism

1992 • 43 citations

Dexamethasone Suppresses Elastin Gene Expression in Human Skin Fibroblasts in Culture

1994 • 27 citations

Regulation of the human elastin promoter in chick embryo cells

1993 • 25 citations

Glucocorticoid-induced tropoelastin expression is mediated via transforming growth factor-beta 3

1996 • 20 citations

Antisense S-Oligonucleotide against Tranforming Growth Factor- &beta;<sub>1</sub> Inhibits Proteoglycan Synthesis in Arterial Wall

1994 • 13 citations

Cited By (0)

Loading...