Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

1993 • 1,197 citations

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens.

1988 • 713 citations

Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis.

1991 • 528 citations

The Leishmaniases in biology and medicine

1987 • 390 citations

Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major.

1989 • 374 citations

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma.

1993 • 345 citations

Immunology of Leishmaniasis

1993 • 337 citations

The Interaction of Leishmania Species with Macrophages

1992 • 323 citations

Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis

1993 • 277 citations

Fusion of Host Cell Secondary Lysosomes with the Parasitophorous Vacuoles ofLeishmania mexicana-inlected Macrophages

1975 • 266 citations

Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis.

1991 • 231 citations

Determination of the cytokine profile in American cutaneous leishmaniasis using the polymerase chain reaction

1993 • 197 citations

Functional heterogeneity of CD4+ T cells in leishmaniasis

1989 • 171 citations

Host Resistance to the Khartoum Strain of Leishmania donovani

1958 • 149 citations

Leishmania donovani-reactive Th1- and Th2-like T-cell clones from individuals who have recovered from visceral leishmaniasis

1993 • 140 citations

Genetics of Resistance to Bacterial and Parasitic Infection

1988 • 121 citations

Induction of Th1 and Th2 CD4+ subsets during murine Leishmania major infection

1991 • 102 citations

Cytokine interactions in experimental cutaneous leishmaniasis. Interleukin 4 synergizes with interferon‐γ to activate murine macrophages for killing of Leishmania major amastigotes

1991 • 82 citations

Murine hepatic accessory cells support the proliferation of Th1 but not Th2 helper T lymphocyte clones.

1989 • 71 citations

Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana.

1995 • 67 citations

Influence of Lsh, H-2, and an H-11-linked gene on visceralization and metastasis associated with Leishmania mexicana infection in mice

1989 • 62 citations

Dichotomy of the human T cell response to Leishmania antigens. II. Absent or Th2-like response to gp63 and Thl-like response to lipophosphoglycan- associated protein in cells from cured visceral leishmaniasis patients

1994 • 61 citations

GENETIC ANALYSIS OF LEISHMANIA MEXICANA INFECTION IN MICE: SINGLE GENE (Scl‐2) CONTROLLED PREDISPOSITION TO CUTANEOUS LESION DEVELOPMENT

1990 • 59 citations

Immunoregulatory pathways in murine leishmaniasis: different regulatory control during Leishmania mexicana mexicana and Leishmania major infections.

1985 • 44 citations

Acquisition of cell-mediated immunity to Leishmania. I. Primary T-cell activation detected by IL-2 receptor expression.

1987 • 28 citations

Genetic Control of Systemic Leishmania major Infection: Identification of Subline Differences for Susceptibility to Disease

1985 • 20 citations