Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport

New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

1994 • 2,554 citations

Brefeldin A: insights into the control of membrane traffic and organelle structure.

1992 • 1,848 citations

Perturbation of vesicular traffic with the carboxylic ionophore monensin

1983 • 890 citations

The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae.

1996 • 839 citations

Cholesterol and the Golgi Apparatus

1993 • 819 citations

Order of events in the yeast secretory pathway

1981 • 804 citations

Methods in yeast genetics, laboratory manual

1987 • 733 citations

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1996 • 623 citations

Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

1990 • 618 citations

Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae

1979 • 518 citations

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

1998 • 512 citations

The RING finger domain: a recent example of a sequence—structure family

1996 • 464 citations

Brefeldin A Acts to Stabilize an Abortive ARF–GDP–Sec7 Domain Protein Complex

1999 • 441 citations

Golgi-disturbing agents

1998 • 375 citations

Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins

1998 • 370 citations

Specific Retrieval of the Exocytic SNARE Snc1p from Early Yeast Endosomes

2000 • 363 citations

Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide Structure

1998 • 344 citations

A Novel RING Finger Protein Complex Essential for a Late Step in Protein Transport to the Yeast Vacuole

1997 • 304 citations

Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin

1999 • 266 citations

Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis

1999 • 265 citations

Two syntaxin homologues in the TGN/endosomal system of yeast

1998 • 258 citations

SPHINGOLIPID FUNCTIONS INSACCHAROMYCES CEREVISIAE: Comparison to Mammals

1998 • 257 citations

Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell?

1997 • 219 citations

Cloning of the late genes in the ergosterol biosynthetic pathway ofSaccharomyces cerevisiae—A review

1995 • 195 citations

Multiple sorting pathways between the late Golgi and the vacuole in yeast

1998 • 192 citations

Vam2/Vps41p and Vam6/Vps39p Are Components of a Protein Complex on the Vacuolar Membranes and Involved in the Vacuolar Assembly in the Yeast Saccharomyces cerevisiae

1997 • 171 citations

The F-Box Protein Rcy1p Is Involved in Endocytic Membrane Traffic and Recycling Out of an Early Endosome in Saccharomyces cerevisiae

2000 • 168 citations

Specific Sterols Required for the Internalization Step of Endocytosis in Yeast

1999 • 166 citations

Purification and Cloning of a Brefeldin A-inhibited Guanine Nucleotide-exchange Protein for ADP-ribosylation Factors

1999 • 155 citations

Molecular Mechanisms of Endocytosis

1997 • 147 citations

Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

1998 • 136 citations

Vac7p, a Novel Vacuolar Protein, Is Required for Normal Vacuole Inheritance and Morphology

1997 • 131 citations

Retrograde Traffic Out of the Yeast Vacuole to the TGN Occurs via the Prevacuolar/Endosomal Compartment

1998 • 126 citations

Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p

1999 • 126 citations

23 Yeast Mutant and Plasmid Collections

1998 • 125 citations

p200 ARF–GEP1: A Golgi-localized guanine nucleotide exchange protein whose Sec7 domain is targeted by the drug brefeldin A

1999 • 121 citations

Tlg2p, a Yeast Syntaxin Homolog That Resides on the Golgi and Endocytic Structures

1998 • 113 citations

Stepwise assembly of the lipid-linked oligosaccharide in the endoplasmic reticulum of Saccharomyces cerevisiae: identification of the ALG9 gene encoding a putative mannosyl transferase.

1996 • 110 citations

Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway.

1993 • 108 citations

Protein prenylation in eukaryotic microorganisms: genetics, biology and biochemistry

1994 • 99 citations

Proteins Needed for Vesicle Budding from the Golgi Complex Are Also Required for the Docking Step of Homotypic Vacuole Fusion

2000 • 94 citations

A Yeast t-SNARE Involved in Endocytosis

1998 • 92 citations

Structure of synaptogyrin (p29) defines novel synaptic vesicle protein.

1995 • 86 citations

The yeast multidrug resistance pump, Pdr5p, confers reduced drug resistance in erg mutants of Saccharomyces cerevisiae

1999 • 82 citations

Biochemical characterization and subcellular localization of the sterol C‐24(28) reductase, Erg4p, from the yeast Saccharomyces cerevisiae

2000 • 76 citations

The See1p homologue Vps45p binds to the syntaxin Tlg2p

1998 • 72 citations

Induction of Endocytic Vesicles by Exogenous C6-ceramide

1999 • 60 citations

Large-scale phenotypic analysis—the pilot project on yeast chromosome III

1997 • 58 citations

Chemotyping of yeast mutants using robotics

1999 • 53 citations

Mso1p: A yeast protein that functions in secretion and interacts physically and genetically with Sec1p

1997 • 37 citations

Generation ofSaccharomyces cerevisiae deletants and basic phenotypic analysis of eight novel genes from the left arm of chromosome XIV

1998 • 13 citations

A mutation in the secretion pathway of the yeast Yarrowia lipolytica that displays synthetic lethality in combination with a mutation affecting the signal recognition particle

1999 • 12 citations