Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

Improved method for high efficiency transformation of intact yeast cells

1992 • 3,258 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 gene

1979 • 1,080 citations

The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases

1997 • 939 citations

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

1997 • 886 citations

Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes

1997 • 685 citations

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G.

1996 • 679 citations

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.

1993 • 660 citations

The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

1998 • 632 citations

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

1989 • 561 citations

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

1994 • 511 citations

Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae.

1994 • 495 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

Premature translational termination triggers mRNA decapping

1994 • 399 citations

Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure.

1993 • 378 citations

A common function for mRNA 5' and 3' ends in translation initiation in yeast.

1995 • 374 citations

Turnover Mechanisms of the Stable Yeast PGK1 mRNA

1995 • 341 citations

Life and death in the cytoplasm: messages from the 3′ end

1997 • 335 citations

An essential component of the decapping enzyme required for normal rates of mRNA turnover

1996 • 328 citations

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

1997 • 314 citations

Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs.

1995 • 294 citations

Primary structure and transcription of an amplified genetic locus: the CUP1 locus of yeast.

1984 • 279 citations

Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen.

1995 • 278 citations

Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast.

1995 • 278 citations

snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.

1995 • 248 citations

Mutations affecting stability and deadenylation of the yeast MFA2 transcript.

1992 • 228 citations

A family of versatile centromeric vectors designed for use in the sectoring-shuffle mutagenesis assay in Saccharomyces cerevisiae

1988 • 221 citations

Translation Initiation and Ribosomal Biogenesis: Involvement of a Putative rRNA Helicase and RPL46

1990 • 204 citations

The Mechanisms of mRNA Degradation in Eukaryotes

1999 • 204 citations

Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA

1994 • 174 citations

Mutations in trans-Acting Factors Affecting mRNA Decapping in Saccharomyces cerevisiae

1996 • 168 citations

RNA Recognition Motif 2 of Yeast Pab1p Is Required for Its Functional Interaction with Eukaryotic Translation Initiation Factor 4G

1998 • 165 citations

The yeast SIS1 protein, a DnaJ homolog, is required for the initiation of translation

1993 • 150 citations

Lethal and temperature-sensitive mutations and their suppressors identify an essential structural element in U2 small nuclear RNA.

1990 • 147 citations

Purification and characterization of an activity from Saccharomyces cerevisiae that catalyzes homologous pairing and strand exchange.

1987 • 132 citations

Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities

1991 • 112 citations

The most abundant small cytoplasmic RNA of Saccharomyces cerevisiae has an important function required for normal cell growth.

1989 • 105 citations

Making sense of nonsense in yeast

1996 • 99 citations

An Intron in the Genes for U3 Small Bucleolar RNAs of the Yeast Saccharomyces cerevisiae

1990 • 86 citations

An Efficient Strategy To Isolate Full-Length cDNAs Based on an mRNA Cap Retention Procedure (CAPture)

1995 • 79 citations

CaSm: an Sm-like protein that contributes to the transformed state in cancer cells.

1997 • 45 citations