Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

The Golgi apparatus (complex)-(1954-1981)-from artifact to center stage.

1981 • 990 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes.

1986 • 847 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Order of events in the yeast secretory pathway

1981 • 804 citations

The fungal vacuole: composition, function, and biogenesis

1990 • 758 citations

Methods in yeast genetics, laboratory manual

1987 • 733 citations

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene

1989 • 684 citations

Progress in Unraveling Pathways of Golgi Traffic

1985 • 615 citations

ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding protein

1991 • 604 citations

Structure of a yeast pheromone gene (MFα): A putative α-factor precursor contains four tandem copies of mature α-factor

1982 • 587 citations

Brefeldin A redistributes resident and itinerant Golgi proteins to the endoplasmic reticulum.

1989 • 581 citations

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

1982 • 579 citations

A Critical Evaluation of the Nitrogen Assimilation Tests Commonly Used in the Classification of Yeasts

1946 • 530 citations

'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles

1991 • 524 citations

Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.

1988 • 519 citations

DNA topoisomerase-targeting antitumor drugs can be studied in yeast.

1988 • 490 citations

β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin

1991 • 489 citations

Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus.

1988 • 488 citations

The Golgi complex: In vitro veritas?

1992 • 481 citations

Enzymes Required for Yeast Prohormone Processing

1988 • 446 citations

Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant.

1991 • 415 citations

Glycosylation and processing of prepro-α-factor through the yeast secretory pathway

1984 • 410 citations

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

1988 • 389 citations

Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.

1990 • 384 citations

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

1991 • 378 citations

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin

1991 • 376 citations

Binding of ARF and β-COP to Golgi Membranes: Possible Regulation by a Trimeric G Protein

1991 • 359 citations

[44] Methods for studying the yeast vacuole

1991 • 346 citations

Reconstitution of SEC gene product-dependent intercompartmental protein transport

1988 • 332 citations

Purification and properties of H+-translocating, Mg2+-adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae.

1985 • 316 citations

Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information.

1988 • 287 citations

Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy.

1992 • 278 citations

Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae.

1991 • 268 citations

The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol.

1989 • 259 citations

Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation.

1989 • 249 citations

Localization of components involved in protein transport and processing through the yeast Golgi apparatus.

1991 • 247 citations

Secretion in yeast: Reconstitution of the translocation and glycosylation of α-factor and invertase in a homologous cell-free system

1986 • 216 citations

Post-Golgi membrane traffic: brefeldin A inhibits export from distal Golgi compartments to the cell surface but not recycling.

1992 • 204 citations

Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells.

1986 • 172 citations

Glycosylation site binding protein and protein disulfide isomerase are identical and essential for cell viability in yeast.

1991 • 137 citations

Intracellular Sorting and Processing of a Yeast Vacuolar Hydrolase: Proteinase A Propeptide Contains Vacuolar Targeting Information

1988 • 121 citations

Targeting and processing of glycophorins in murine erythroleukemia cells: use of brefeldin A as a perturbant of intracellular traffic.

1989 • 104 citations

Prepro-alpha-factor has a cleavable signal sequence.

1988 • 99 citations

Sec15 protein, an essential component of the exocytotic apparatus, is associated with the plasma membrane and with a soluble 19.5S particle.

1991 • 91 citations

Yeast KEX2 protease and mannosyltransferase I are localized to distinct compartments of the secretory pathway

1989 • 81 citations

The Yeast Gene ERG6 Is Required for Normal Membrane Function but Is Not Essential for Biosynthesis of the Cell-Cycle-Sparking Sterol

1989 • 75 citations

A Putative Zinc Finger Protein, Saccharomyces cerevisiae Vpsl8p, Affects Late Golgi Functions Required for Vacuolar Protein Sorting and Efficient α-Factor Prohormone Maturation

1991 • 74 citations

Revision of the oligosaccharide structures of yeast carboxypeptidase Y.

1990 • 72 citations

In vitro reconstitution of intercompartmental protein transport to the yeast vacuole.

1990 • 65 citations

Sterol methylation in Saccharomyces cerevisiae

1984 • 65 citations

Brefeldin A affects early events but does not affect late events along the exocytic pathway in pancreatic acinar cells.

1992 • 39 citations