Retroviral DNA Integration Directed by HIV Integration Protein in Vitro

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1985 • 706 citations

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.

1986 • 483 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1990 • 411 citations

Retroviral DNA integration: Structure of an integration intermediate

1988 • 397 citations

Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

1989 • 392 citations

A nucleoprotein complex mediates the integration of retroviral DNA.

1989 • 381 citations

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1989 • 311 citations

Structural characterization of reverse transcriptase and endonuclease polypeptides of the acquired immunodeficiency syndrome retrovirus

1986 • 308 citations

Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: implications for retrovirus integration.

1980 • 280 citations

Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence

1989 • 260 citations

Integration of human immunodeficiency virus type 1 DNA in vitro.

1990 • 257 citations

Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection

1984 • 244 citations

A defined system for the DNA strand-transfer reaction at the initiation of bacteriophage Mu transposition: protein and DNA substrate requirements.

1985 • 183 citations

A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration.

1984 • 182 citations

Human immunodeficiency virus integration in a cell-free system

1990 • 182 citations

Genetic recombination of human immunodeficiency virus

1989 • 180 citations

The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus.

1984 • 164 citations

Integration of mini-retroviral DNA: a cell-free reaction for biochemical analysis of retroviral integration.

1989 • 111 citations

Sequence requirements for integration of Moloney murine leukemia virus DNA in vitro

1990 • 81 citations

Sequence of the circle junction of human immunodeficiency virus type 1: implications for reverse transcription and integration

1990 • 78 citations

Requirement of the avian retrovirus pp32 DNA binding protein domain for replication

1984 • 59 citations

Analysis of long terminal repeat circle junctions of human immunodeficiency virus type 1

1990 • 47 citations