How Damaged is the Biologically Active Subpopulation of Transfected DNA?

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

The radiobiology of cultured mammalian cells

1967 • 687 citations

Simian Virus 40 Deoxyribonucleic Acid Synthesis: the Viral Replicon

1972 • 609 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Enhancer elements

1983 • 576 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Oncogenes in solid human tumours

1982 • 467 citations

Patterns of Integration of DNA Microinjected into Cultured Mammalian Cells: Evidence for Homologous Recombination Between Injected Plasmid DNA Molecules

1982 • 417 citations

Isolation of the β-tubulin gene from yeast and demonstration of its essential function in vivo

1983 • 409 citations

High mutation frequency in DNA transfected into mammalian cells.

1983 • 338 citations

Transforming DNA integrates into the host chromosome

1981 • 311 citations

Direct transfer of cloned genes from bacteria to mammalian cells.

1980 • 291 citations

A dominant role for DNA secondary structure in forming hypersensitive structures in chromatin

1983 • 273 citations

Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein

1982 • 236 citations

Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene

1983 • 235 citations

Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes.

1982 • 229 citations

Rearrangement and mutagenesis of a shuttle vector plasmid after passage in mammalian cells.

1983 • 207 citations

Somatic Cells Efficiently Join Unrelated DNA Segments End-to-End

1982 • 186 citations

A map of temperature-sensitive mutants of simian virus 40

1975 • 178 citations

Integration and excision of SV40 DNA from the chromosome of a transformed cell

1980 • 169 citations

Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell

1980 • 164 citations

Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer

1982 • 156 citations

Recombination During Gene Transfer into Mouse Cells Can Restore the Function of Deleted Genes

1983 • 148 citations

High-Efficiency Ligation and Recombination of DNA Fragments by Vertebrate Cells

1983 • 148 citations

DNA sequence homology and chromosomal deletion at a site of SV40 DNA integration

1982 • 143 citations

Homologous recombination in mammalian cells mediates formation of a functional gene from two overlapping gene fragments.

1983 • 129 citations

Factors governing the expression of a bacterial gene in mammalian cells.

1981 • 126 citations

Differences in the DNA of the inactive X chromosomes of fetal and extraembryonic tissues of mice

1983 • 123 citations

The inheritance of methylation patterns in vertebrates

1981 • 119 citations

The genetic analysis of recombination using adenovirus overlapping terminal DNA fragments

1983 • 114 citations

Cancer genes come of age

1983 • 98 citations

In vivo recombination of cauliflower mosaic virus DNA

1982 • 81 citations

Rescue of in vitro generated mutants of cloned cauliflower mosaic virus genome in infected plants

1981 • 80 citations

Evolutionary variants of simian virus 40: Cellular DNA sequences and sequences at recombinant joints of substituted variants

1978 • 78 citations

Clustered illegitimate recombination events in mammalian cells involving very short sequence homologies

1983 • 72 citations

Indiscriminate recombination in simian virus 40-infected monkey cells.

1980 • 70 citations

Simian virus 40 recombinants are produced at high frequency during infection with genetically mixed oligomeric DNA.

1979 • 68 citations

Segments of simian virus 40 DNA spanning most of the leader sequence of the major late viral messenger RNA are dispensable.

1979 • 67 citations

Integrated Simian Virus 40 DNA: Nucleotide Sequences at Cell-Virus Recombinant Junctions

1981 • 62 citations

Defined oligomeric SV40 DNA: A sensitive probe of general recombination in somatic cells

1980 • 57 citations

DNA-mediated gene transfer: recombination between cotransferred DNA sequences and recovery of recombinants in a plasmid.

1982 • 50 citations

Analysis of recombination in mammalian cells using SV4O genome segments having homologous overlapping termini

1980 • 50 citations

Recombination in SV40-infected cells: Viral DNA sequences at sites of circularization of transfecting linear DNA

1981 • 43 citations

The uptake of SV40 DNA by nonpermissive cells in the presence of DEAE-dextran

1971 • 34 citations

Mammalian cell functions mediating recombination of genetic elements

1980 • 34 citations

Interference in SV40 DNA infections: A possible basis for cellular competence

1978 • 34 citations

Simian virus 40-permissive cell interactions: selection and characterization of spontaneously arising monkey cells that are resistant to simian virus 40 infection

1976 • 29 citations

Genetic analysis of host range mutant viruses suggests an uncoating defect in simian virus 40-resistant monkey cells

1977 • 26 citations

Infection of primary African green monkey cells with SV40 monomeric and dimeric DNA

1971 • 14 citations

Biologic activity of oligomeric forms of SV40 DNA

1978 • 9 citations

Preparation of a “Functional Library” of African Green Monkey DNA Fragments Which Substitute for the Processing/Polyadenylation Signal in the Herpes Simplex Virus Type 1 Thymidine Kinase Gene

1983 • 7 citations