Preparation of a “Functional Library” of African Green Monkey DNA Fragments Which Substitute for the Processing/Polyadenylation Signal in the Herpes Simplex Virus Type 1 Thymidine Kinase Gene

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

The Genome of Simian Virus 40

1978 • 948 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event

1970 • 770 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

The organization and expression of histone gene families

1981 • 501 citations

Genetic and physical linkage of exogenous sequences in transformed cells

1980 • 486 citations

Efficient infection of monkey cells with DNA of simian virus 40.

1981 • 419 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Biogenesis and characterization of histone messenger RNA in HeLa cells

1972 • 383 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

1979 • 355 citations

SV40 gene expression is modulated by the cooperative binding of T antigen to DNA

1981 • 300 citations

Exons encode functional and structural units of chicken lysozyme.

1980 • 273 citations

Tissue-specific expression of mouse α-amylase genes: Nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland

1980 • 259 citations

The Role of the Poly(A) Sequence in Mammalian Messenger RN

1981 • 254 citations

Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues

1982 • 241 citations

Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.

1979 • 238 citations

DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus.

1981 • 231 citations

Deoxythymidine kinase induced in HeLa TK- cells by herpes simplex virus type I and type II. II. Purification and characterization.

1976 • 141 citations

Generation of authentic 3′ termini of an H2A mRNA in vivo is dependent on a short inverted DNA repeat and on spacer sequences

1982 • 139 citations

Structure of two adenovirus type 12 transforming polypeptides and their evolutionary implications

1980 • 97 citations

[125I]deoxycytidine used in a rapid, sensitive, and specific assay for herpes simplex virus type 1 thymidine kinase

1977 • 91 citations

The Regulatory Function of Poly(A) and Adjacent 3' Sequences in Translated RNA

1982 • 80 citations

Kinetic studies of herpes simplex virus type 1-encoded thymidine and thymidylate kinase, a multifunctional enzyme.

1979 • 77 citations

Control of breakdown of the polyadenylate sequence in mammalian polyribosomes: role of poly(adenylic acid)-protein interactions

1977 • 68 citations

Reiteration Frequency of the Histone Genes in the Genome of the Amphibian, Xenopus laevis

1976 • 47 citations

Construction and Characterization of Viable Deletion Mutants of Simian Virus 40 Lacking Sequences near the 3′ End of the Early Region

1982 • 36 citations

Loss of the polyadenylate segment from mammalian messenger RNA

1980 • 35 citations

Phosphorylation of 5-iodo-5'-amino-2',5',dideoxyuridine by herpes simplex virus type 1 encoded thymidine kinase.

1979 • 32 citations

Simian virus 40-rabbit beta-globin recombinants lacking late mRNA splice sites express cytoplasmic RNAs with altered structures

1982 • 29 citations

Phenotypic Switching in Cells Transformed with the Herpes Simplex Virus Thymidine Kinase Gene

1982 • 28 citations